Results 161 to 170 of about 41,661 (291)

Shared decision-making in prostate cancer treatment: selecting an androgen deprivation therapy option. [PDF]

Future Oncol
Collins SP, Maculaitis MC, Chakoian M.
europepmc   +1 more source

Social and Anxiety‐Like Behaviors Are Affected in Juvenile Mice With Gli2+/− but Not Gli3+/𝛥699 Genetic Modifications

Brain and Behavior, Volume 16, Issue 6, June 2026.
Across Gli3+/Δ699, Gli2+/−, and combined Gli2+/−;Gli3+/Δ699 mice (males and females, with wild‐type controls), GLI2 and GLI3 differentially regulate anogenital distance and juvenile behavior, with amplified effects under combined disruption, whereas circulating steroids and sexually dimorphic nucleus area remain unchanged. Created in BioRender. Niepsuj,
Thomas Niepsuj, Rithika Nurani, Leykza Carreras‐Simons, Wade Bushman, Joan S. Jorgensen, Walid A. Farhat, Anthony P. Auger   +6 more
wiley   +1 more source

Penile Metastasis From Dedifferentiated Prostate Cancer With Low PSA Levels: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Penile metastasis from prostate cancer is rare and is associated with a poor prognosis; however, there is currently a lack of high‐level evidence to guide the management of this condition. This case report describes a 68‐year‐old male with prostate cancer who developed a penile metastasis during follow‐up. This occurred despite stable prostate‐
Xianqi Shen, Xinwen Nian, Bosi Zhang, Yan Wang, Zhenyang Dong, Min Qu, Xu Gao   +6 more
wiley   +1 more source

Cervical Skip Metastases and Extensive Central Venous Thrombosis as the Initial Presentation of High‐Grade Prostate Adenocarcinoma With Discordant PI‐RADS 3 Findings: A Case Report and Diagnostic Challenge

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Prostate cancer can initially present with cervical lymph node “skip” metastases and extensive central venous thrombosis, without pelvic or bone involvement. A PI‐RADS 3 lesion on mpMRI does not exclude high‐grade (Gleason 5 + 5 = 10) disease. Unexplained thrombosis in elderly men warrants prostate cancer investigation.
Yuchun Luo, Benhui Lai, Juncheng Huang
wiley   +1 more source

Hepatocyte growth factor/c‐Met signaling axis in human diseases: Mechanistic insights and therapeutic potential

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Figure 1 visually summarizes the core biological functions and therapeutic potential of the HGF/c‐Met signaling axis. Abstract Hepatocyte growth factor (HGF) is a multifunctional cytokine that activates the tyrosine kinase activity of its specific receptor, c‐Met (mesenchymal–epithelial transition factor).
Hongqin Sun, Hao Shu, Qian Zhang, Jishan Zheng, Yunyan Ma, Dengwang Chen, Jidong Zhang, Tao Song   +7 more
wiley   +1 more source

Quantitative Morphometric Response to Neoadjuvant Androgen-Deprivation Therapy and Its Prognostic Role After Radical Prostatectomy. [PDF]

Res Rep Urol
Afanasiev Y, Vozianov S, Danylets R, Grygorenko V, Shulyak O, Sosnin M.   +5 more
europepmc   +1 more source

Mortality and Androgen Deprivation Therapy as Salvage Treatment for Biochemical Recurrence after Primary Therapy for Clinically Localized Prostate Cancer

, 2017
PURPOSE: Androgen deprivation therapy is often used as salvage treatment in men with rising prostate specific antigen after initial radical prostatectomy or radiotherapy for clinically localized prostate cancer.
Keating, Nancy L, Yood, Marianne U, Cassidy-Bushrow, Andrea E, Potosky, Arnold L, Tsai, Huei-Ting, Zhou, Yingjun, Fu, Alex Z, Smith, Matthew R, Haque, Reina, Van Den Eeden, Stephen K, Aaronson, David S   +10 more
core  

Testosterone and docetaxel treatment effect on mortality risk in nonmetastatic high‐risk prostate cancer: A predictive biomarker analysis

Cancer, Volume 132, Issue 11, 1 June 2026.
Abstract Background Prostate cancer (PC) arising in patients with low testosterone is often more aggressive and less responsive to androgen deprivation therapy (ADT). This study evaluated whether baseline testosterone group (low vs. normal) modifies the mortality benefit of adding docetaxel to radiation therapy (RT) and ADT in nonmetastatic high‐risk ...
Johnathan Zeng, Ming‐Hui Chen, Jing Wu, Wanling Xie, Praful Ravi, Paul Nguyen, Howard Sandler, Anthony V. D’Amico   +7 more
wiley   +1 more source

MITF Gain‐of‐Function Mutation in Metastatic Prostate Cancer: A Rare Finding With Potential Therapeutic Significance

Cancer Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Prostate cancer is the most common non‐cutaneous malignancy in men and remains a leading cause of cancer‐related mortality, particularly in aggressive variants. These tumors are usually associated with alterations in TP53, RB1, and PTEN.
Paul J. Pecorin, Nyembezi Dhliwayo, Matthew Demetrious, Ludimila Cavalcante, Veronica Rodriguez‐Bravo, Josep Domingo Domenech, Thomas Westbrook   +6 more
wiley   +1 more source

Myosteatosis and Sarcopenic Obesity in Men Receiving Androgen Deprivation Therapy for Prostate Cancer: Rationale for Mechanism-Driven Multimodal Intervention. [PDF]

Cancers (Basel)
Kumar NB, Parker N, Zhang J, Pow-Sang J, Park JY, Schell MJ.   +5 more
europepmc   +1 more source