Results 191 to 200 of about 41,661 (291)

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, Volume 2, Issue 2, Page 280-308, June 2026.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Diet-Microbiome Relationships in Prostate-Cancer Survivors with Prior Androgen Deprivation-Therapy Exposure and Previous Exercise Intervention Enrollment. [PDF]

Microorganisms
Raber J, O'Niel A, Kasschau KD, Pederson A, Robinson N, Guidarelli C, Chalmers C, Winters-Stone K, Sharpton TJ.   +8 more
europepmc   +1 more source

The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao, Yuheng Qin, Haoyu Wan, Guang Lu, Han‐Ming Shen   +4 more
wiley   +1 more source

Forecasting Trends in Androgen Deprivation Therapy Intensification for Metastatic Hormone-Sensitive Prostate Cancer: A Retrospective Population-Based Cohort and Time-Series Analysis. [PDF]

Curr Oncol
Khosh Kish E, Dvorani E, Saskin R, Wilton AS, Satkunasivam R, Aminoltejari K, Hird A, Berscheid K, Roy S, Morgan SC, Ong M, Jiang DM, Gotto GT, Shayegan B, Kulkarni GS, Breau RH, Lalani AA, Nguyen DD, Wallis CJD.   +18 more
europepmc   +1 more source

Optimizing acupuncture dosing for hormone therapy‐induced hot flashes in cancer patients: A regression‐based analysis and narrative review

Precision Medical Sciences, Volume 15, Issue 2, Page 135-146, June 2026.
Our analysis reveals a clear dose–response relationship between acupuncture sessions and the reduction of hormone therapy‐induced hot flashes. A threshold of approximately 10 sessions establishes a robust quantitative benchmark for achieving clinically meaningful neuro‐autonomic modulation and symptom relief.
Jiaming Cui, Xinyao Wei, Lulu Bin, Shaoxin Sun, Yu Liu, Tao Yang, Zhishun Liu, Jiani Wu   +7 more
wiley   +1 more source

Intermittent androgen deprivation therapy for biochemical recurrence or prostate-specific antigen (PSA) persistence after radical prostatectomy: efficacy and prognostic factors. [PDF]

Transl Androl Urol
Chen J, Chen Q, Yan X, Wang Z, Wang Y, Zhang Y, Zhang J, Xu J, Zhang J, Zhang D, Liu Q, Lan W, Jiang J.   +12 more
europepmc   +1 more source

The Prognostic Significance of Radiographic Progression Without PSA Progression in Patients With Metastatic Hormone‐Sensitive Prostate Cancer Treated With First‐Line ARPI Therapy

The Prostate, Volume 86, Issue 8, Page 882-890, June 2026.
ABSTRACT Background Radiographic progression (RP) without prostate‐specific antigen (PSA) elevation has emerged as a clinically important pattern in the androgen receptor pathway inhibitors (ARPI) era, but its prevalence and prognostic significance in real‐world metastatic hormone‐sensitive prostate cancer (mHSPC) cohorts remain unclear.
Takeshi Tsutsumi, Shogo Yamazaki, Takuya Matsuda, Takuya Tsujino, Taizo Uchimoto, Takafumi Yanagisawa, Keiichiro Mori, Wataru Fukuokaya, Fumihiko Urabe, Masanobu Saruta, Atsuhiko Yoshizawa, Shingo Toyoda, Saizo Fujimoto, Kyosuke Nishio, Moritoshi Sakamoto, Tatsuo Fukushima, Ko Nakamura, Kazuki Nishimura, Keita Nakamori, Tomohisa Matsunaga, Yuki Yoshikawa, Ryoichi Maenosono, Kiyoshi Takahara, Teruo Inamoto, Takahiro Kimura, Kazutoshi Fujita, Kazumasa Komura, Haruhito Azuma   +27 more
wiley   +1 more source

Influence of androgen deprivation therapy on physical performance and muscle strength in prostate cancer patients - a systematic review. [PDF]

Rep Pract Oncol Radiother
Szarzyńska Z, Barczak I, Giermek K, Garczyk A, Mardas M, Stelmach-Mardas M.   +5 more
europepmc   +1 more source

Renal cancer survival and use of 5alpha-reductase inhibitors or androgen deprivation therapy. [PDF]

BMC Urol
Lipponen O, Pöyhönen A, Kotsar A, Veitonmäki T, Tammela TL, Sunela K, Murtola TJ.   +6 more
europepmc   +1 more source

Castration Resistance Accelerates Prostate Cancer Kinetics

The Prostate, Volume 86, Issue 9, Page 1021-1027, June 15, 2026.
ABSTRACT Background Prostate cancer can be an indolent disease with which patients can live for many years. Thus, an understanding of how therapy and its ensuing resistance affect prostate cancer kinetics may guide efforts to determine optimal timing of therapy initiation.
Sheila Jonnatan, Luka Cavka, Angelo M. De Marzo, Samuel R. Denmeade, Mark C. Markowski, Emmanuel S. Antonarakis, Bruce J. Trock, Catherine H. Marshall, Ravi A. Madan, David J. Einstein, Laura A. Sena   +10 more
wiley   +1 more source