Results 241 to 250 of about 41,661 (291)

Androgen deprivation therapy for prostate cancer

Expert Opinion on Pharmacotherapy, 2008
Androgen deprivation continues to play a crucial role in the treatment of advanced and metastatic prostate cancer. In the 65 years since its use was first described, urologists and medical oncologists have developed new and innovative ways to manipulate the hypothalamic-pituitary-gonadal axis with the goal of alleviating symptoms and prolonging the ...
Eric A Singer   +2 more
exaly   +3 more sources

Review of Cardiovascular Risk of Androgen Deprivation Therapy and the Influence of Race in Men with Prostate Cancer

open access: yesCancers, 2023
Androgen deprivation therapy is the cornerstone of prostate cancer therapy. Recent studies have revealed an association between androgen deprivation therapy and cardiovascular adverse effects such as myocardial infarction and stroke.
James Fradin   +2 more
exaly   +4 more sources

Cardiovascular Effects of Androgen Deprivation Therapy in Prostate Cancer: Contemporary Meta-Analyses [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 2020
International audienceAndrogen deprivation therapy is a cornerstone of prostate cancer treatment. Pharmacological androgen deprivation includes gonadotropin-releasing hormone agonism and antagonism, androgen receptor inhibition, and CYP17 (cytochrome ...
Jiun-Ruey Hu   +2 more
exaly   +2 more sources

Androgen deprivation therapy complications

Endocrine-Related Cancer, 2014
Androgen deprivation therapy (ADT) is increasingly used to treat advanced prostate cancer and is also utilised as adjuvant or neo-adjuvant treatment for high-risk disease. The resulting suppression of endogenous testosterone production has deleterious effects on quality of life, including hot flushes, reduced mood and cognition and diminished sexual ...
Carolyn A, Allan   +4 more
openaire   +2 more sources

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