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Risk of Alzheimer's disease and Parkinson's disease following androgen deprivation therapy in a real world nationwide cohort. [PDF]
Jeon HL +5 more
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The impact of androgen deprivation therapy and novel hormonal therapy on thyroid hormone levels in prostate cancer patients: a systematic review and meta-analysis. [PDF]
Chu H, Qu Y.
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Androgen deprivation therapy for prostate cancer
Expert Opinion on Pharmacotherapy, 2008Androgen deprivation continues to play a crucial role in the treatment of advanced and metastatic prostate cancer. In the 65 years since its use was first described, urologists and medical oncologists have developed new and innovative ways to manipulate the hypothalamic-pituitary-gonadal axis with the goal of alleviating symptoms and prolonging the ...
Eric A Singer +2 more
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Androgen deprivation therapy is the cornerstone of prostate cancer therapy. Recent studies have revealed an association between androgen deprivation therapy and cardiovascular adverse effects such as myocardial infarction and stroke.
James Fradin +2 more
exaly +4 more sources
Cardiovascular Effects of Androgen Deprivation Therapy in Prostate Cancer: Contemporary Meta-Analyses [PDF]
International audienceAndrogen deprivation therapy is a cornerstone of prostate cancer treatment. Pharmacological androgen deprivation includes gonadotropin-releasing hormone agonism and antagonism, androgen receptor inhibition, and CYP17 (cytochrome ...
Jiun-Ruey Hu +2 more
exaly +2 more sources
Androgen deprivation therapy complications
Endocrine-Related Cancer, 2014Androgen deprivation therapy (ADT) is increasingly used to treat advanced prostate cancer and is also utilised as adjuvant or neo-adjuvant treatment for high-risk disease. The resulting suppression of endogenous testosterone production has deleterious effects on quality of life, including hot flushes, reduced mood and cognition and diminished sexual ...
Carolyn A, Allan +4 more
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