Results 101 to 110 of about 2,496,118 (309)

In silico comparison between the mutated and wild-type androgen receptors and their influence on the selection of optimum androgenic receptor blockers for the treatment of prostate cancer [version 4; peer review: 2 approved]

F1000Research
Background: Prostate cancer is a disease that occurs in men aged more than 50 years. In Iraq, 8.89 men per 100,000 population suffer from prostate cancer, with the incidence being 14,016 cases and mortality being 6,367 cases.
Hany Akeel Al-Hussaniy, Mohammed J. AL-Zobaidy, Zahraa S. Al-tameemi   +2 more
doaj   +1 more source

Deletion of the Androgen Receptor in Adipose Tissue in Male Mice Elevates Retinol Binding Protein 4 and Reveals Independent Effects on Visceral Fat Mass and on Glucose Homeostasis [PDF]

, 2012
Kerry J. McInnes, Lee B. Smith, Nicole I. Hunger, Philippa T. K. Saunders, Ruth Andrew, Brian R. Walker   +5 more
openalex   +1 more source

Data from Selective Androgen Receptor Modulator RAD140 Inhibits the Growth of Androgen/Estrogen Receptor–Positive Breast Cancer Models with a Distinct Mechanism of Action

, 2023
Ziyang Yu, Suqin He, Dannie Wang, Hitisha Patel, Chris P. Miller, Jeffrey L. Brown, Gary Hattersley, Jamal Saeh   +7 more
openalex   +1 more source

Androgen receptor signalling transactivator lncRNAs PRNCR1 and PCGEM contribute to PCOS pathogenesis [PDF]

, 2023
Mudasar Nabi, Shayaq Ul Abeer Rasool, Sairish Ashraf, Syed Mudasir Ahmad, Shajrul Amin   +4 more
openalex   +1 more source

Biocompatible Chemistry: A Plug‐and‐Play Toolbox for Chemical Biology Research

ChemBioChem, EarlyView.
The “plug‐and‐play” nature of biocompatible chemistry makes it a powerful toolbox for investigating complicated biological systems and producing drug leads for clinical usages. This review summarizes the commonly used biocompatible reactions and the recent advances of their representative applications in chemical biology research, thus highlighting the
Adam R. Lovato, Zeng Lin, Qingfei Zheng
wiley   +1 more source

Synthesis of the Abiraterone Derivatives 5α‐ and 5β‐Δ1‐Abiraterone and Structural Determination of an Unknown Metabolite in Human Serum Derived from Oral Abiraterone Acetate

ChemBioChem, EarlyView.
Abiraterone (Abi) acetate, a prostate cancer treatment, is orally administered and hydrolyzed, and multiple metabolites are produced in serum by various enzymes. Two novel Abi derivatives, 5α‐ and 5β‐Δ1‐abiraterone, are synthesized. Then, an unknown metabolite in serum is identified to be 5β‐Δ1‐abiraterone based on its extracted ion chromatogram ...
Noboru Hayama, Shizuyo Horiyama, Ryoma Okamoto, Yukina Nishi, Manae Yada, Ryuji Higashida, Jun Haginaka, Yoshihide Usami   +7 more
wiley   +1 more source

Dietary Berberine Reduced Oxido‐Inflammatory Stress in Rats' Livers and Kidneys, Supplemented from Prepuberty to Adulthood

ChemFoodChem, EarlyView.
Berberine (BER) demonstrates significant protective effects on the hepatorenal system in rats, mediated through various cellular and molecular mechanisms spanning from the prepubertal stage through adulthood. These mechanisms encompass antioxidant, anti‐inflammatory, and anti‐apoptotic activities, in addition to modulation of essential signalling ...
Solomon Owumi, Bayode Oluwawibe, Harieme Agbarogi, Moses T. Otunla, Uche Arunsi, Jesutosin O. Babalola, Chioma Irozuru, Chima Amadi, Ahmad Altayyar   +8 more
wiley   +1 more source

Reseptor Androgen dan Organ Reproduksi Pria

JKS (Jurnal Kedokteran Syiah Kuala), 2006
Abstrak.   Hormon  androgen  berperan  penting    dalam   perkembangan   scksual    individu    jaruan.   Mormon   androgen yang  penting  adalah   hormon  testosteron   dan  hormon  dyindrotestosteron.
Zulfitri Zulfitri
doaj  

Chemometric Optimization of BF3·OEt2‐Mediated Cyclization of Cannabidiol to Rare Δ⁴‐ and Iso‐THC Isomers

Chemistry – A European Journal, EarlyView.
Find the path! The present paper points out the potentialities of chemometrics tools to design selective BF3·OEt2 catalyzed procedures for the preparation of Δ⁹‐THC, Δ⁸‐THC, Δ⁸‐iso‐THC, Δ⁴‐iso‐THC, Δ⁴(⁸)‐iso‐THC, by simply tuning the initial concentration of CBD, the amount of the Lewis acid, the reaction time as well as the nature of the solvent ...
Arianna Bini, Lisa Rita Magnaghi, Valeria Cavalloro, Alessandra Bonanni, Stefano Protti, Daniele Merli   +5 more
wiley   +1 more source

MP03-03 ANDROGEN RECEPTOR PROMOTES HIGH-DOSE VITAMIN C INDUCED KIDNEY CAOX CRYSTALS FORMATION VIA AR-MIR-182-TXNRD1/GLRX2 BASED MECHANISMS [PDF]

, 2019
Haoran Liu, Kun Tang, Ye Tao, Xiaoqi Yang, Kehua Jiang, Fa Sun   +5 more
openalex   +1 more source