Results 141 to 150 of about 231,777 (344)

Non‐steroidal antiandrogens act as AF‐1 agonists under conditions of high androgen‐receptor expression [PDF]

, 2007
Hiroaki Fuse, Shigeru Korenaga, Matomo Sakari, Takashi Hiyama, Takeshi Ito, Kôichi Kimura, Shigeaki Kato   +6 more
openalex   +1 more source

Data from Targeting Androgen Receptor (AR)→IL12A Signal Enhances Efficacy of Sorafenib plus NK Cells Immunotherapy to Better Suppress HCC Progression

, 2023
Liang Shi, Hui Lin, Gonghui Li, Renan Jin, Junjie Xu, Yin Sun, Wen‐Lung Ma, Shuyuan Yeh, Xiujun Cai, Chawnshang Chang   +9 more
openalex   +1 more source

Antidiabetic Potential of Ligands from NEIST_PMIB_06, Bacterium Associated with Hawaijar (Fermented Soy Food): Insight from in Vitro and in Silico Studies

ChemFoodChem, EarlyView.
ABSTRACT In this study, a bacterium (NEIST_PMIB_06) was isolated from Hawaijar, a fermented soy food from Manipur, Northeast India. The bacterium was inoculated and incubated to isolate bioactive compounds. Liquid‐liquid extraction was performed to obtain extracts (cell‐free and cell‐based), and their efficacy was evaluated.
A Ibeyaima, Hiranmoy Barman, Prasenjit Manna   +2 more
wiley   +1 more source

Oxytocin Effects on Food Stimulus Processing and Food Intake in Females With or Without Binge Eating Disorder

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Binge eating disorder (BED) is maintained by increased food‐related incentive salience, which is reflected by an attentional bias for food. Oxytocin acutely attenuates this bias in patients with anorexia nervosa and reduces food intake in males with normal or increased body weight.
Julia Nannt, Mechteld M. van den Hoek Ostende, Brunna Tuschen‐Caffier, Markus Heinrichs, Daniel Sippel, Manfred Hallschmid, Jennifer Svaldi   +6 more
wiley   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Androgen receptor [PDF]

Science-Business eXchange, 2009
  +6 more sources

Androgen receptor inhibitor ameliorates pulmonary arterial hypertension by enhancing the apoptosis level through suppressing the Notch3/Hes5 pathway

Frontiers in Pharmacology
BackgroundPulmonary arterial hypertension (PAH) exhibits significant gender differences in prognosis, with male patients typically showing worse outcomes than females.
Jiayan Sun, Jiayan Sun, Jiayan Sun, Jiancheng Lin, Jiancheng Lin, Jiancheng Lin, Di Yin, Di Yin, Di Yin, Zetao Pan, Zetao Pan, Zetao Pan, Yuheng Ye, Yuheng Ye, Yuheng Ye, Yi Wang, Yi Wang, Yi Wang, Xiaowan Wang, Xiaowan Wang, Xiaowan Wang, Qiang Guo, Qiang Guo, Qiang Guo, Qiang Guo   +24 more
doaj   +1 more source

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk, Christopher Faulk, Jessica LaRocca, Jan van Benthem, Francesco Marchetti   +4 more
wiley   +1 more source

Sigma1 Targeting to Suppress Aberrant Androgen Receptor Signaling in Prostate Cancer. [PDF]

, 2017
Suppression of androgen receptor (AR) activity in prostate cancer by androgen depletion or direct AR antagonist treatment, although initially effective, leads to incurable castration-resistant prostate cancer (CRPC) via compensatory mechanisms including ...
Anderson, Kelsey N., Chen, Nan, Kania, Blase, Kim, Felix J., Knudsen, Karen E., Longen, Charles G., Maher, Christina M., Ostrander, William F., Oyer, Halley M., Salvino, Joseph M., Thomas, Jeffrey D.   +10 more
core   +1 more source

Androgen receptor genomic regulation.

Translational andrology and urology, 2013
The transcriptional activity of the androgen receptor (AR) is not only critical for the normal development and function of the prostate but also pivotal to the onset and progression of prostate cancer (PCa). The studies of AR transcriptional regulation were previously limited to a handful of AR-target genes.
Jin, Hong-Jian, Kim, Jung, Yu, Jindan
openaire   +2 more sources