Results 271 to 280 of about 230,623 (311)

Maternal, childhood and adolescent influences on Leydig cell functional capacity and circulating INSL3 concentration in young adults: Importance of childhood infections and body mass index

Andrology, EarlyView.
Abstract Background The constitutive Leydig cell hormone insulin‐like peptide 3 (INSL3) is considered a good estimate of the adult Leydig cell functional capacity and appears to remain relatively consistent throughout adult male life, only gradually declining into old age.
Richard Ivell, Bilal Tulumcu, Waleed Alhujaili, Ravinder Anand‐Ivell   +3 more
wiley   +1 more source

Toxicities of novel androgen receptor pathway inhibitor targeted therapies in advanced prostate cancer. [PDF]

Curr Opin Urol
Iaxx R, Teyssonneau D, Fallaha C, Grouthier V, Roubaud G.   +4 more
europepmc   +1 more source

Genetics of infertility and “assisted fertilization” in the Bible: The case of Abraham and his family

Andrology, EarlyView.
Abstract Couple infertility is a very ancient medical condition. One of the first descriptions of familial infertility/subfertility is contained in the first book of the Bible, Genesis, written in the 10th century BC and reporting tales from the oral tradition even occurred about 800 years earlier.
Manuela Simoni, Frank Tüttelmann, Livio Casarini   +2 more
wiley   +1 more source

ZBTB7B modulates the androgen receptor as an upstream regulator via colocalization and direct binding in LNCaP prostate cancer cells. [PDF]

Transl Cancer Res
Im E, Park SY, Sim DY, Cho AR, Kil BJ, Kim B, Shim BS, Kim SH.   +7 more
europepmc   +1 more source

The aporetic dialogs of Modena on gender differences: Is it all about testosterone? Episode III: Mathematics

Andrology, EarlyView.
Abstract This report is the transcript of what was discussed in a convention at the Endocrinology Unit in Modena, Italy, in the form of the aporetic dialogs of ancient Greece. It is the third episode of a series of four discussions on the differences between males and females, with a multidisciplinary approach. In this work, the role of testosterone in
Giulia Brigante, Francesco Costantino, Alessio Bellelli, Stefano Boni, Chiara Furini, Rita Cucchiara, Manuela Simoni   +6 more
wiley   +1 more source

The interconnection between androgen receptor and DNA damage response pathways in prostate cancer. [PDF]

Curr Urol
Sands M, Adams S, Lee J, Li M, Wang M, Walsh T, Leon L, Zablah A, Haerens M, Liu Z, Li J.   +10 more
europepmc   +1 more source

Low testosterone levels in men at age 31 associates with future risk of prediabetes and type 2 diabetes: A birth cohort study

Andrology, EarlyView.
Abstract Objective We aimed to investigate the association of a low serum testosterone concentration with the risk of abnormal glucose metabolism (i.e., prediabetes and type 2 diabetes) in men at a 15‐year follow‐up. Study population and methods In a population birth cohort, men with low testosterone (testosterone < 12.1 nmol/L, n = 136) and normal ...
Tuomisto A, Pinola P, Pesonen P, Franks S, Martikainen H, Tapanainen JS, Niinimäki M, Morin‐Papunen L   +7 more
wiley   +1 more source

Muscle Strength and Power Changes With Gender‐Affirming Hormone Therapy

Andrology, EarlyView.
ABSTRACT Background Androgen receptors are highly expressed in upper body muscles, but changes in maximal muscle strength and power in major upper body muscles have not been investigated during gender‐affirming hormone therapy (GAHT). Objective To assess prospective changes in maximal muscle strength and muscle power from before and after 1 year of ...
Mathilde Kamp Nørlund, Jakob Lindberg Nielsen, Marianne Skovsager Andersen, Rikke Hjortebjerg, Laust Frisenberg Buhl, Anne Pernille Hermann, Camilla Viola Buskbjerg Palm, Tine Taulbjerg Kristensen, Jan Frystyk, Per Aagaard, Jonas Mathiesen, Dorte Glintborg, Louise Lehmann Christensen   +12 more
wiley   +1 more source

Efficacy and Safety of Combination Androgen-Receptor Signaling Inhibitors, Denosumab, and Local Radiotherapy for Poly-Metastatic Prostate Cancer. [PDF]

Cancer Rep (Hoboken)
Kawase M, Kawase K, Tobisawa Y, Iinuma K, Nakane K, Koie T.   +5 more
europepmc   +1 more source

INSL3 Expression in Leydig Cells is a Biomarker for Immunocastration in Boars: Transcriptional Evidence

Andrology, EarlyView.
ABSTRACT Background Study aimed to obtain insights into physiological responses to immunocastration in pubertal boars by evaluating effects of alternative vaccination protocols and identifying a reliable immunocastration biomarker. Objectives It was hypothesized that the timing of gonadotropin‐releasing hormone (GnRH) suppression by immunocastration ...
Nina Batorek Lukač, Martin Škrlep, Klavdija Poklukar, Petra Ferjan, Volker Stefanski, Gregor Fazarinc, Milka Vrecl   +6 more
wiley   +1 more source