Results 171 to 180 of about 17,593 (256)

Mineralocorticoid receptor antagonists: Efficacy and safety in chronic kidney disease

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract The mineralocorticoid receptor (MR) has a multifaceted role in normal physiologic functions. However, research has uncovered the deleterious consequences of overactivation of the MR. It has been implicated in chronic kidney disease (CKD) via its strong association with glomerulosclerosis, interstitial fibrosis, proteinuria, and decline in ...
Amy K. Mottl   +2 more
wiley   +1 more source

Beyond the chaos: How architecture structures tumour biology

open access: yesThe FEBS Journal, EarlyView.
Tissue architecture shapes tumour initiation and progression through multiple interconnected layers continuously remodelled over time. This review outlines how physical forces, biochemical cues, cellular niches and systemic influences contribute to tumour evolution.
Lea Dörner   +3 more
wiley   +1 more source

Exploring the impact of Cabotegravir‐Rilpivirine long‐acting on weight gain, body composition and quality of life in adults living with HIV

open access: yesHIV Medicine, EarlyView.
Abstract Introduction Long‐acting injectable antiretroviral therapy (ART) with Cabotegravir (CAB) and Rilpivirine (RPV) offers an alternative to daily oral regimens, improving adherence and patient satisfaction. However, its impact on body composition and metabolism remains underexplored.
Andrea De Vito   +13 more
wiley   +1 more source

TMPRSS2 Expression in Lung Tissue of Prostatic Adenocarcinoma Patients: Androgen Deprivation Therapy and Relevance to SARS-CoV-2 Infection. [PDF]

open access: yesCurr Issues Mol Biol
Riveros Angel M   +7 more
europepmc   +1 more source

Thriving in Nursing Work: The Association Between Self‐Reports and Biomarkers of Stress, Inflammation and Neuroplasticity

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To examine whether self‐reported thriving at work is associated with biomarkers of stress, inflammation, neuroplasticity and neurodegeneration in nurses. Design A cross‐sectional study. Methods An online questionnaire measuring thriving at work was administered to nurses in a teaching hospital in Michigan, U.S. over 5 weeks in 2024.
Judith E. Arnetz   +8 more
wiley   +1 more source

Annual Research Review: What processes are dysregulated among emotionally dysregulated youth? – a systematic review

open access: yesJournal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 516-546, April 2025.
Proliferation of the term “emotion dysregulation” in child psychopathology parallels the growing interest in processes that influence negative emotional reactivity. While it commonly refers to a clinical phenotype where intense anger leads to behavioral dyscontrol, the term implies etiology because anything that is dysregulated requires an impaired ...
Joseph C. Blader   +2 more
wiley   +1 more source

Perspectives and Requirements of Patients with Prostate Cancer on Mobile Health Interventions During Androgen Deprivation Therapy: A Descriptive Qualitative Study

open access: yesJournal of Clinical Nursing, EarlyView.
ABSTRACT Aim To explore the perceptions of patients with prostate cancer undergoing androgen deprivation therapy towards mobile health interventions. Design The study employed a qualitative descriptive design. Methods Seventeen participants were recruited from tertiary care hospitals from November 2022 to June 2023. The collected data were subsequently
Hongfan Yin, Chen Pan, Jia Gu, Yan Yang
wiley   +1 more source

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