An elderly male patient with extramammary Paget disease of the scrotum and multiple metastases was treated with fractionated FLASH‐RT (40 Gy in 5 fractions) in the scrotal lesion. Abstract Objective Ultrahigh‐dose‐rate radiotherapy (FLASH‐RT) has been shown to reduce radiation‐induced normal tissue injury in preclinical studies.
Hui Luo +14 more
wiley +1 more source
Androgen Effects on Amyloid Precursor Protein Processing Pathways in Cancer: A Systematic Review. [PDF]
Alhadrami M +5 more
europepmc +1 more source
Castration Resistance Accelerates Prostate Cancer Kinetics
ABSTRACT Background Prostate cancer can be an indolent disease with which patients can live for many years. Thus, an understanding of how therapy and its ensuing resistance affect prostate cancer kinetics may guide efforts to determine optimal timing of therapy initiation.
Sheila Jonnatan +10 more
wiley +1 more source
Muscle pain in a woman with congenital adrenal hyperplasia due to 21-hydroxylase deficiency resolved with testosterone therapy. A case report with 10 years of follow-up. [PDF]
Hubska J +6 more
europepmc +1 more source
ABSTRACT Purpose Previous studies have demonstrated an association between PSMA‐PET SUVmax and poorer survival outcomes in patients with mCRPC. However, limited data are available in mHSPC. We aim to investigate the relationship between baseline PSMA‐PET SUVmax and rPFS in patients with mHSPC.
Cevat İlteriş Kıkılı +11 more
wiley +1 more source
Adipose-androgen crosstalk in polycystic ovary syndrome: mechanisms and therapeutic implications. [PDF]
Ni M, Lei H, Ye T, Wang Y.
europepmc +1 more source
ABSTRACT Background Early deep prostate‐specific antigen (PSA) decline after the initiation of androgen receptor signaling inhibitor (ARSI) therapy is associated with favorable long‐term outcomes in metastatic castration‐sensitive prostate cancer (mCSPC).
Kazuma Yukihiro +14 more
wiley +1 more source
Intraindividual Comparison of the Anabolic Steroid Hormone Profile Between Hormonal Contraceptive Use and the Phases of a Natural Menstrual Cycle in a Recreational Athlete: A Single-Case Observational Study. [PDF]
Nolte J +4 more
europepmc +1 more source
ABSTRACT Introduction The clinical relevance of HER2 expression profile in solid cancers has expanded with the evolving landscape of HER2 targeting agents. This systematic review and meta‐analysis aim to detail the prevalence of HER (over)expression in prostate cancer and identify patient/disease subgroups with enriched HER2 overexpression.
Jacky T. F. Luk +10 more
wiley +1 more source
Steroid hormones and nephrolithiasis: regulation of urine components metabolism and inflammation. [PDF]
Zhang X +4 more
europepmc +1 more source

