Results 201 to 210 of about 61,244 (265)

Activity of Galeterone in Hepatocellular Carcinoma and Description of Androgen Receptor Expression in Mouse Liver

, 2019
Riley Mullins
openalex   +1 more source

Liquid biopsy in genitourinary oncology: Current clinical applications and future prospects across prostate, bladder, and renal cancers

UroPrecision, EarlyView.
Abstract Liquid biopsy has emerged as a transformative approach in oncology, providing minimally invasive access to tumor‐derived biomarkers with applications across diagnosis, prognosis, therapeutic guidance, and disease monitoring. This literature review synthesizes evidence from 125 studies evaluating circulating tumor DNA, circulating tumor cells ...
Kirolos Eskandar
wiley   +1 more source

Metastatic prostate cancer recurrence within a percutaneous computed tomography guided needle biopsy tract: A rare case report

UroPrecision, EarlyView.
Abstract Background Metastatic prostate cancer tumor seeding within a percutaneous biopsy tract is rare. While reports of tumor seeding following perineal and transrectal prostate biopsies exist, no cases of prostate cancer tumor seeding along a metastatic percutaneous bone biopsy tract detected by prostate specific membrane antigen (PSMA) positron ...
Thomas Neerhut, Thomas McMaster, Abigail Attwell‐Heap, Michael Kreltszheim   +3 more
wiley   +1 more source

Novel reference gene microseminoprotein‐beta based prostate cancer antigen 3 urine test: Enhanced diagnostic performance for prostate cancer and feasibility of non‐digital rectal examination urine sampling

UroPrecision, EarlyView.
Abstract Background The diagnosis of prostate cancer (PCa) is limited by low specificity and invasiveness. This study aims to establish a highly accurate, noninvasive reverse transcription‐quantitative polymerase chain reaction (RT‐qPCR)‐based urinary prostate cancer antigen 3 (PCA3) assay system and explore the feasibility of using first‐morning urine
Jianglei Xu, Lu Yang, Cong Shi, Yiwei Jiang, Jing Chen, Xiaoxiao Sun, Xuejuan Gao, Xian Wang, Jianzhong Jiang, Xiuzhi Duan, Xuchu Wang, Yiyi Xie, Zhixian Yu, Zhihua Tao, Xiaobing Dou, Chunyu Jin   +15 more
wiley   +1 more source

EFFECT OF CHINOLON DERIVATIVES ON SPERMIOGENESIS AND TESTIS ANDROGEN RECEPTORS INVESTIGATED AT WISTAR RATS

, 2019
D. Başak, Y. Aytekin, T. Altuğ, A. Öner, E. ÖZDİLER   +4 more
openalex   +1 more source

Microbial metabolism of host androgens regulates enteric nervous system function.

Lagomarsino, Valentina N
openalex   +1 more source

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Androgens and androgen receptors in breast cancer

The Journal of Steroid Biochemistry and Molecular Biology, 2007
Aromatase (CYP19) converts adrenal and ovarian androgens into estrogens, which supports the growth of estrogen-dependent breast cancers. Anti-aromatase agents are displacing antiestrogens as the first-line treatment for estrogen receptor positive breast cancers.
B, Nicolás Díaz-Chico, F, Germán Rodríguez, Ana, González, Raquel, Ramírez, Cristina, Bilbao, A, Cabrera de León, A, Aguirre Jaime, Ricardo, Chirino, Domingo, Navarro, Juan C, Díaz-Chico   +9 more
openaire   +2 more sources

Androgens and Bone [PDF]

Endocrine Reviews, 2004
Loss of estrogens or androgens increases the rate of bone remodeling by removing restraining effects on osteoblastogenesis and osteoclastogenesis, and also causes a focal imbalance between resorption and formation by prolonging the lifespan of osteoclasts and shortening the lifespan of osteoblasts.
Dirk Vanderschueren, Liesbeth Vandenput, Steven Boonen   +2 more
exaly   +3 more sources

Androgens, Antiandrogens and Androgen Receptor Abnormalities

European Urology, 1996
Information on the molecular structure of the human androgen receptor has increased insight into the molecular mechanism of action of androgens and antiandrogens. It has also facilitated the study of molecular defects in the androgen receptor gene associated with prostate cancer.
C W, Kuil, A O, Brinkmann
openaire   +2 more sources

Androgen antagonists in androgen target tissues

Pharmacology & Therapeutics, 1984
Most antiandrogens appear to act by binding to the androgen receptor and competitively inhibiting the binding of testosterone and cihydrotestosterone to the receptor. Focusing on those compounds which appear to inhibit androgen receptor mediated responses this review discusses the chemistry of those antiandrogens which have been studied to the extent ...
D J, Tindall, C H, Chang, T J, Lobl, G R, Cunningham   +3 more
openaire   +2 more sources