Results 241 to 250 of about 141,437 (356)

Exploring the Reproductive Toxicity of Bisphenol S Through a Network Toxicology and Molecular Docking Analysis

Pediatric Discovery, EarlyView.
Utilizing network toxicology, molecular docking, and dynamic simulations to investigate the potential reproductive toxicity of bisphenol S (BPS). ABSTRACT The aim of this study was to investigate the potential reproductive toxicity of bisphenol S (BPS) and the related molecular mechanisms through a network toxicology approach.
Siyuan Wang, Yan Fu, Xu Huang, Qitong Guo, Xiangqin Zheng, Shengde Wu, Lianju Shen, Guanghui Wei   +7 more
wiley   +1 more source

Computational Optimization and Binding Affinity Analysis of SH14B: A High-Selectivity Non-Steroidal Androgen Receptor Antagonist for Topical Application

Melvin Sewell
openalex   +1 more source

THE INFLUENCE OF KISSPEPTIN-10 ON EXPRESSION OF ANDROGEN AND KISSPEPTIN RECEPTORS IN RAT TESTES AFTER STRESS EXPOSURE [PDF]

V. Golts, M. Kostina, A. Perova, T. Reypolskaya, D. Tanyanskiy, P. Khokhlov, E. Sekste, S. Tsikunov, A. Bayramov, A. Lebedev, E. Bychkov, P Shabanov   +11 more
openalex   +1 more source

MicroRNA‐130a‐3p Targets the Androgen‐Related Transcription Factor MAFB: Effects on Proliferation, Migration, Apoptosis, and Cell Cycle in Hypospadias

Pediatric Discovery, EarlyView.
MicroRNA‐130a‐3p targets and inhibits MAFB expression, leading to the development of hypospadimas. MicroRNA‐130a‐3p inhibits the expression of MAFB, disrupts the normal processes of cell proliferation, migration, cell apoptosis, and cycle progression, and ultimately leads to the development of hypospadias.
Jiaxin Zhou, Yixuan Wang, Zhicheng Zhang, Qiang Zhang, Zhenmin Liu, Hongsong Chen, Xingguo Luo, Chunlan Long, Lianju Shen, Xing Liu, Guanghui Wei   +10 more
wiley   +1 more source

Adrenal Androgens, Estrone, and Insulin-Like Growth Factor 1 Are Associated with Thelarche without Gonadotropin Activation in Girls.

Horm Res Paediatr
Burtsov S, Viitasalo A, Soininen S, Häkkinen MR, Auriola S, Mäntyselkä A, Voutilainen R, Jääskeläinen J, Lakka TA.   +8 more
europepmc   +1 more source

Distinguishing direct androgenic signaling from local aromatization in the lateral septum. [PDF]

Proc Natl Acad Sci U S A
Huang D, Dong J.
europepmc   +1 more source

Echo-Rift XL: Biochemical Profile and Docking Mechanics of Non-Steroidal Androgen Receptor Antagonist SH-1 (SH14B)

Melvin Sewell
openalex   +1 more source

A low-androgen environment sustains the functionally reduced sGC states required to restrain castration-resistant prostate cancer growth via elevated cGMP levels [PDF]

Clara I. Troccoli, Beatriz Mateo-Victoriano, Annie V. Beuve, Mercè Jordà, Janaki Neela Sharma, Priyamvada Rai   +5 more
openalex   +1 more source

Proteomic Analysis of Mixed Cell Membrane Extracts From Triple‐Negative Breast Cancer Cell Lines Revealed Broad Metabolic Reprogramming Associated With Tumor Progression

PROTEOMICS, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) represents the most aggressive subtype with limited therapeutic options and the poorest clinical outcomes. Using high‐resolution nUPLC‐QTOF‐MS/MS, we performed comprehensive proteomic profiling of TNBC cell lines representing disease progression stages: HCC‐1937 (stage IIB), HCC‐1599 (stage IIIA), and MDA ...
Claudia Sissely Chaviano‐Montes de Oca, Violeta Larios‐Serrato, María Luisa Labra‐Barrios, Emmanuel Ríos‐Castro, Carlos Alberto Castañón‐Sánchez, Rodolfo Moreno‐Castillo, Erika Beatriz Ángeles‐Morales, Juan Pedro Luna‐Arias   +7 more
wiley   +1 more source