Results 21 to 30 of about 59,669 (148)
Contemporary treatment options for male hypogonadism
Journal of Education, Health and Sport, 2023 Introduction Male hypogonadism is a disease in which testicular function is impaired. Its symptoms are due to testosterone deficiency and most of them show low specificity.
Paweł Sojka +9 more
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Hormones and Signaling Pathways Involved in the Stimulation of Leydig Cell Steroidogenesis
Endocrines, 2023 Leydig cells, located in the testis interstitial space, are the primary source of testosterone in males. Testosterone plays critical roles in both reproductive and metabolic functions and therefore is essential for male health.
Karine de Mattos +2 more
doaj +1 more source
A Potential Role and Contribution of Androgens in Placental Development and Pregnancy
Life, 2021 Successful pregnancy requires the establishment of a highly regulated maternal–fetal environment. This is achieved through the harmonious regulation of steroid hormones, which modulate both maternal and fetal physiology, and are critical for pregnancy ...
Agata M. Parsons, Gerrit J. Bouma
doaj +1 more source
Muscle Growth and Anabolism in Intensive Care Survivors (GAINS) trial: a pilot randomised controlled trial [PDF]
Acute and Critical Care, 2022 Background To explore the feasibility, safety, and potential benefits of administration of the anabolic steroid nandrolone to patients in the recovery phase from critical illness weakness.
Matthew H Anstey +9 more
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Androgen regulation of the androgen receptor coregulators [PDF]
BMC Cancer, 2008 Abstract Background The critical role of the androgen receptor (AR) in the development of prostate cancer is well recognized. The transcriptional activity of AR is partly regulated by coregulatory proteins. It has been suggested that these coregulators could also be important in the progression of prostate cancer. The
Urbanucci, Alfonso +4 more
openaire +4 more sources
Androgens in cervical cancer: Their role in epidemiology and biology
iScienceSummary: This comprehensive review delves into the significance of androgens in cervical cancer, examining both epidemiological evidence and the underlying biological mechanisms.
Yang Gu, Qing Mu, Dali Cheng
doaj +1 more source
Androgens and prostate disease
Asian Journal of Andrology, 2014 A growing body of literature has established the anabolic benefi ts of testosterone (T) therapy in hypogonadal men. However, there remains a paucity of data regarding the risks of exogenous androgen use in older men and the potential for adverse effects ...
Lori A Cooper, Stephanie T Page
doaj +1 more source
Insights into Androgen Receptor Action in Lung Cancer
Endocrines, 2023 Sex hormones and their receptors play a crucial role in human sexual dimorphism and have been traditionally associated with hormone-dependent cancers like breast, prostate, and endometrial cancer.
Darko Durovski +2 more
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Membrane androgen receptors may mediate androgen reinforcement [PDF]
Psychoneuroendocrinology, 2010 Anabolic-androgenic steroid (AAS) abuse is widespread. Moreover, AAS are reinforcing, as shown by self-administration in rodents. However, the receptors that transduce the reinforcing effects of AAS are unclear. AAS may bind to classical nuclear androgen receptors (ARs) or membrane receptors. We used two approaches to examine the role of nuclear ARs in
Satoru M, Sato +3 more
openaire +2 more sources
Reproductive Biology and Endocrinology, 2011 Background Effects of androgens on follicle maturation have been controversial for some time. Here, we review the potential of their applications in improving human ovulation induction, based on human and animal data, reported in the literature.
Gleicher Norbert +2 more
doaj +1 more source