Results 31 to 40 of about 4,498 (180)

Large language models unlock large text corpora in the search for data on medicinal plants and fungi

PLANTS, PEOPLE, PLANET, EarlyView.
Millions of people worldwide depend on plants and fungi for their healthcare needs, yet our understanding of which species are used medicinally—and how—remains fragmented and incomplete. As part of Kew's Plants for Health service, we developed a pipeline to mine large text corpora for information on natural products, initially focusing on the medicinal
Adam Richard‐Bollans, Francesco Civita, Tiziana A. Cossu, Ifra Saifi, Kristina Patmore, Caroline Wilkinson, Bob Allkin   +6 more
wiley   +1 more source

Effects of Andrographis paniculata and Orthosiphon stamineus Extracts on the Glucuronidation of 4-Methylumbelliferone in Human UGT Isoforms

Molecules, 2010
The effects of Andrographis paniculata and Orthosiphon stamineus extracts on the in vitro glucuronidation of 4-methylumbelliferone (4MU) by recombinant human UGTs, UGT1A1, UGT1A3, UGT1A6, UGT1A7, UGT1A8, UGT1A10, UGT2B7 and UGT2B15 were determined.
Sabariah Ismail, Nur Aziah Hanapi, Mohd Rohaimi Ab Halim, Verawan Uchaipichat, Peter I. Mackenzie   +4 more
doaj   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Estimation of Andrographolides and Gradation of Andrographis paniculata Leaves Using Near Infrared Spectroscopy Together With Support Vector Machine

Frontiers in Pharmacology, 2021
Andrographis paniculata (Burm. F) Nees, has been widely used for upper respiratory tract and several other diseases and general immunity for a historically long time in countries like India, China, Thailand, Japan, and Malaysia.
Dilip Sing, Subhadip Banerjee, Shibu Narayan Jana, Ranajoy Mallik, Sudarshana Ghosh Dastidar, Kalyan Majumdar, Amitabha Bandyopadhyay, Rajib Bandyopadhyay, Pulok K. Mukherjee, Pulok K. Mukherjee   +9 more
doaj   +1 more source

Research on the Mechanism of Natural Products Acting on Chronic Obstructive Pulmonary Disease

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This figure illustrates that approximately 80 natural compounds exert therapeutic effects against chronic obstructive pulmonary disease by targeting pathological mechanisms such as airway inflammation, oxidative stress, airway remodeling, mucus hypersecretion, emphysema, protease–antiprotease imbalance, apoptosis, and autophagy.
Shuna Wei, Xiaoju Liu
wiley   +1 more source

Antimalarial Activity of Andrographis Paniculata Ness‘s N-hexane Extract and Its Major Compounds

Open Chemistry, 2019
Andrographis paniculata Ness is one of the plants that is under explored and could contain potentially active substances to serve as an antimalarial. Structure investigation of major compounds that have responsibility for the antimalarial activity of ...
Prakoso Nurcahyo Iman, Zakiyah Zahrah Nur, Liyanita Arida, Rubiyanto Dwiarso, Fitriastuti Dhina, Ramadani Arba Pramundita, Kamari Azlan, Mow Sim Kooi   +7 more
doaj   +1 more source

A Combined Treatment with Berberine and Andrographis Exhibits Enhanced Anti-Cancer Activity through Suppression of DNA Replication in Colorectal Cancer

Pharmaceuticals, 2022
The high morbidity and mortality associated with colorectal cancer (CRC) are largely due to the invariable development of chemoresistance to classic chemotherapies, as well as intolerance to their significant toxicity.
Yinghui Zhao, Souvick Roy, Chuanxin Wang, Ajay Goel   +3 more
doaj   +1 more source

TCM‐Guided Targeted Therapies Against NLRP3 Inflammasome in NAFLD

Immunity, Inflammation and Disease, Volume 14, Issue 6, June 2026.
This graphical abstract illustrates TCM syndrome differentiation‐guided targeted strategies against NLRP3 inflammasome‐mediated non‐alcoholic fatty liver disease (NAFLD). Metabolic dysfunction and gut‐liver axis dysregulation drive NAFLD progression, activating the NLRP3 inflammasome (comprising NLRP3, ASC, caspase‐1) to trigger cytokine release (IL‐1β,
Yanxia Zhang
wiley   +1 more source

The Effectiveness Of Squeeze Of Sambiloto (Andrographis Paniculata) Leaves On The Mortality Of Larvae Aedes Aegypti

Saintika Medika, 2020
Dengue hemorrhagic fever has become a deadly disease since 2013. Dengue fever is a disease caused by dengue virus transmitted to humans through the bite of the Aedes aegypti.
Graffico Eryza Oldiara, Riandini Aisyah, Safari Wahyu Jatmiko, Devi Usdiana Rosyidah, Rochmadina Suci Bestari   +4 more
doaj   +1 more source