Results 31 to 40 of about 845 (162)

Allergens and their associated small molecule ligands—their dual role in sensitization

open access: yesAllergy, Volume 76, Issue 8, Page 2367-2382, August 2021., 2021
Abstract Many allergens feature hydrophobic cavities that allow the binding of primarily hydrophobic small‐molecule ligands. Ligand‐binding specificities can be strict or promiscuous. Serum albumins from mammals and birds can assume multiple conformations that facilitate the binding of a broad spectrum of compounds.
Maksymilian Chruszcz   +9 more
wiley   +1 more source

The scents of androstenone in humans

open access: yesThe Journal of Physiology, 2003
Specific anosmia, the inability to detect a particular odour, has been well documented for decades in human and animal populations. Indeed, the existence of specific anosmias was a favoured argument used to support a receptor‐mediated mechanism of odourant detection prior to the molecular identification of a large family of olfactory G‐protein‐coupled ...
Ricardo C, Araneda, Stuart, Firestein
openaire   +3 more sources

Metabonomic Study on the Plasma of High‐Fat Diet‐Induced Dyslipidemia Rats Treated with Ge Gen Qin Lian Decoction by Ultrahigh‐Performance Liquid Chromatography‐Mass Spectrometry

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021., 2021
Gegen Qinlian decoction (GGQLD) has a definite effect on T2DM in clinic, and it has the effect of lowering blood sugar, improving insulin resistance, and improving the blood lipid level of rats with dyslipidemia, but the intervention mechanism of GGQLD on dyslipidemia has not been clarified.
Ziwei Xu   +8 more
wiley   +1 more source

Gene expression profiles in testis of pigs with extreme high and low levels of androstenone

open access: yesBMC Genomics, 2007
Background: Boar taint is a major obstacle when using uncastrated male pigs for swine production. One of the main compounds causing this taint is androstenone, a pheromone produced in porcine testis.
Bendixen Christian   +8 more
doaj   +1 more source

Transcript profiling of candidate genes in testis of pigs exhibiting large differences in androstenone levels

open access: yesBMC Genetics, 2010
Background Boar taint is an unpleasant odor and flavor of the meat and occurs in a high proportion of uncastrated male pigs. Androstenone, a steroid produced in testis and acting as a sex pheromone regulating reproductive function in female pigs, is one ...
Oeth Paul   +4 more
doaj   +1 more source

Large scale genome-wide association and LDLA mapping study identifies QTLs for boar taint and related sex steroids

open access: yesBMC Genomics, 2011
Background Boar taint is observed in a high proportion of uncastrated male pigs and is characterized by an unpleasant odor/flavor in cooked meat, primarily caused by elevated levels of androstenone and skatole.
Hansen Marianne HS   +6 more
doaj   +1 more source

New investigations around CYP11A1 and its possible involvement in an androstenone QTL characterised in Large White pigs

open access: yesGenetics Selection Evolution, 2011
Background Previously, in boars with extreme androstenone levels, differential expression of the CYP11A1 gene in the testes has been characterised. CYP11A1 is located in a region where a QTL influencing boar fat androstenone levels has been detected in a
Larzul Catherine   +4 more
doaj   +1 more source

IMPLEMENTATION OF GENOMIC INFORMATION IN SELECTION OF BOARS ON SKATOLE AND ANDROSTENONE CONCENTRATIONS [PDF]

open access: yesPoljoprivreda, 2015
Genomic predictors offer an opportunity to overcome the limitations of classical selection against boar taint, and this study evaluated different approaches to obtain such predictors. Samples from 941 pigs were included in a design which was dominated by
Boris Lukić
doaj   +1 more source

Concentrations of Boar Taint Compounds Are Weakly Associated with Sexual Behavior of Young Boars

open access: yesAnimals, 2022
Strategies to control boar taint (BT) in meat relies on the reduction of skatole, indole, and androstenone concentration. This might have unfavorable effects on the libido of breeding boars.
Elena Boschi   +4 more
doaj   +1 more source

Pemenone and Androstenone do not Cross-adapt Reciprocally [PDF]

open access: yesChemical Senses, 1996
Explorations of the qualitative and quantitative differences between the odors of pemenone (PEM), androstenone (AND) and isovaleric acid (IVA) show that they share a number of common perceptual characteristics. Among these are similarities in their odor quality and relative intensity ratings.
D A, Stevens, R J, O'Connell
openaire   +2 more sources

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