Results 1 to 10 of about 41,228 (229)
New England Journal of Medicine, 2018 Aplastic anemia - bone marrow failure (AA) is defined as pancytopenia with hypocellular bone marrow without signs of marrow fibrosis or of presence of abnormal cells. Recent studies showed that most of AA cases might be mediated by immune mechanisms.
Thomas Menter, Alexandar Tzankov
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Current Opinion in Internal Medicine, 2008 Most acquired aplastic anemia is the result of immune-mediated destruction of hematopoietic stem cells causing pancytopenia and an empty bone marrow, which can be successfully treated with either immunosuppressive therapy or hematopoietic stem-cell transplantation.In aplastic anemia, oligoclonally expanded cytotoxic T cells induce apoptosis of ...
Neal S, Young +2 more
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Oncology and Therapy, 2023 Introduction Patients with higher-risk myelodysplastic syndromes (MDS) face considerable challenges in disease management and often require caregiver support.
Pauline Frank +5 more
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Telomere length of various blood and bone marrow cells in patients with aplastic anemia
Онкогематология, 2023 Background. Aplastic anemia proceeds with bone marrow failure and is associated with immunological suppression of normal blood stem cells’ proliferation, which lead to bone marrow aplasia.
A. V. Luchkin +9 more
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Aplastic Anemia Treated with Eltrombopag during Pregnancy
Case Reports in Obstetrics and Gynecology, 2022 Aplastic anemia is a rare blood disorder characterized by pancytopenia and hypocellular bone marrow. In patients with aplastic anemia, pancytopenia sometimes worsens during pregnancy, and relapse of aplastic anemia in pregnancy is common.
Yuri Suminaga +7 more
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Aplastic anemia in China [PDF]
Journal of Translational Internal Medicine, 2018 Abstract Aplastic anemia (AA) is a hematologic disease characterized by pancytopenia. Up to now, severe aplastic anemia (SAA) has been recognized by international and domestic scholars as an autoimmune disease with bone marrow (BM) failure mediated by the hyperfunctional T lymphocytes.
Chunyan Liu, Zonghong Shao
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Cell Transplantation, 2021 The present study aimed to investigate the effect and possible mechanism of recombinant human thrombopoietin (rhTPO) on mouse 32D cells (a mouse myeloid progenitor cell line) treated with serum from patients with aplastic anemia and to elucidate the ...
Juan Qian +7 more
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Archives of Anesthesia and Critical Care, 2022 Aplastic anemia is rare hematological disorder with approximate incidence 1.5-7 cases per million individuals per year. Osteonecrosis, a frequently seen in patients with aplastic anemia.
Shalvi Mahajan +3 more
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The prognosis in aplastic anemia [PDF]
Blood, 1975 Abstract The biphasic shape of the survival curve of 99 patients with aplastic anemia suggested that there may be at least two subgroups of patients with this disease, one with a very short survival and another with a longer survival. Patients who survived for 4 mo or less after the first clinic visit (group A) were different from the ...
Darryl M. Williams +3 more
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Profil Penderita Anemia Aplastik di RSUP Dr. M. Djamil Padang Tahun 2018-2019
Jurnal Ilmu Kesehatan Indonesia, 2021 Background. Aplastic anemia is a failure of the process of formation and development of blood cells that causes a decrease or absence of hematopoietic precursor cells in the bone marrow.
Amanda Rizki +2 more
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