Results 11 to 20 of about 334,579 (212)

Approach to the diagnosis of aplastic anemia.

open access: yesBlood Advances, 2021
Establishing a diagnosis of aplastic anemia (AA) can be challenging, but it is absolutely critical to appropriate management, especially differentiating between acquired and inherited forms of the disease. The hematology field requires updated diagnostic
A. Dezern, J. Churpek
semanticscholar   +1 more source

Predicting response of severe aplastic anemia to immunosuppression combined with eltrombopag

open access: yesHaematologica, 2021
Pretreatment blood counts, particularly an absolute reticulocyte count ≥25×109/L, correlate with response to immunosuppressive therapy in severe aplastic anemia.
Yoshitaka Zaimoku   +6 more
semanticscholar   +1 more source

Aplastic anemia [PDF]

open access: yesCurrent Opinion in Internal Medicine, 2008
Most acquired aplastic anemia is the result of immune-mediated destruction of hematopoietic stem cells causing pancytopenia and an empty bone marrow, which can be successfully treated with either immunosuppressive therapy or hematopoietic stem-cell transplantation.In aplastic anemia, oligoclonally expanded cytotoxic T cells induce apoptosis of ...
Neal S, Young   +2 more
openaire   +2 more sources

Diagnostic work‐up for severe aplastic anemia in children: Consensus of the North American Pediatric Aplastic Anemia Consortium

open access: yesAmerican journal of hematology/oncology, 2021
The North American Pediatric Aplastic Anemia Consortium (NAPAAC) is a group of pediatric hematologist‐oncologists, hematopathologists, and bone marrow transplant physicians from 46 institutions in North America with interest and expertise in aplastic ...
K. Shimano   +25 more
semanticscholar   +1 more source

Aplastic Anemia Treated with Eltrombopag during Pregnancy

open access: yesCase Reports in Obstetrics and Gynecology, 2022
Aplastic anemia is a rare blood disorder characterized by pancytopenia and hypocellular bone marrow. In patients with aplastic anemia, pancytopenia sometimes worsens during pregnancy, and relapse of aplastic anemia in pregnancy is common.
Yuri Suminaga   +7 more
doaj   +1 more source

Peri-Operative Anesthetic Management of a Patient with Aplastic Anemia for Total Hip Replacement: Case Report

open access: yesArchives of Anesthesia and Critical Care, 2022
Aplastic anemia is rare hematological disorder with approximate incidence 1.5-7 cases per million individuals per year. Osteonecrosis, a frequently seen in patients with aplastic anemia.
Shalvi Mahajan   +3 more
doaj   +1 more source

Pesticides and Chemicals as Potential Risk Factors of Aplastic Anemia: A Case–Control Study Among a Pakistani Population

open access: yesClinical Epidemiology, 2021
Introduction Aplastic anemia is a rare and potentially life-threatening hematological disorder with incidence of 1.4 to 14 cases/million. It is associated with exposures to certain environmental chemicals, drugs and infections.
Muhammad Asif Syed   +3 more
semanticscholar   +1 more source

Aplastic Anemia

open access: yesHaematology and Blood Transfusion / Hämatologie und Bluttransfusion, 2020
Treatments of aplastic anemia are comprised of supportive therapy and aplastic anemia-specific therapy aimed at restoring hematopoiesis. Supportive therapies include transfusion, G-CSF, and the administration of iron chelation agents, as well as dealing ...
K. Usuki
semanticscholar   +1 more source

Thrombopoietin Promotes Cell Proliferation and Attenuates Apoptosis of Aplastic Anemia Serum-Treated 32D Cells via Activating STAT3/STAT5 Signaling Pathway and Modulating Apoptosis-Related Mediators

open access: yesCell Transplantation, 2021
The present study aimed to investigate the effect and possible mechanism of recombinant human thrombopoietin (rhTPO) on mouse 32D cells (a mouse myeloid progenitor cell line) treated with serum from patients with aplastic anemia and to elucidate the ...
Juan Qian   +7 more
doaj   +1 more source

Aplastic anemia in China [PDF]

open access: yesJournal of Translational Internal Medicine, 2018
Abstract Aplastic anemia (AA) is a hematologic disease characterized by pancytopenia. Up to now, severe aplastic anemia (SAA) has been recognized by international and domestic scholars as an autoimmune disease with bone marrow (BM) failure mediated by the hyperfunctional T lymphocytes.
Liu, Chunyan, Shao, Zonghong
openaire   +2 more sources

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