Results 11 to 20 of about 24,700 (204)
Genomic landscape of immune checkpoint inhibitor-induced aplastic anemia: a case report [PDF]
Hematological immune-related adverse events caused by immunotherapy are relatively uncommon. Aplastic anemia triggered by immune checkpoint inhibition is rare and its genomic characteristic remains largely unexplored. This case report describes a 42-year-
Nobuyuki Takahashi +24 more
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Introduction Patients with higher-risk myelodysplastic syndromes (MDS) face considerable challenges in disease management and often require caregiver support.
Pauline Frank +5 more
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Most acquired aplastic anemia is the result of immune-mediated destruction of hematopoietic stem cells causing pancytopenia and an empty bone marrow, which can be successfully treated with either immunosuppressive therapy or hematopoietic stem-cell transplantation.In aplastic anemia, oligoclonally expanded cytotoxic T cells induce apoptosis of ...
Neal S, Young +2 more
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Aplastic Anemia Treated with Eltrombopag during Pregnancy
Aplastic anemia is a rare blood disorder characterized by pancytopenia and hypocellular bone marrow. In patients with aplastic anemia, pancytopenia sometimes worsens during pregnancy, and relapse of aplastic anemia in pregnancy is common.
Yuri Suminaga +7 more
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Aplastic anemia is rare hematological disorder with approximate incidence 1.5-7 cases per million individuals per year. Osteonecrosis, a frequently seen in patients with aplastic anemia.
Shalvi Mahajan +3 more
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The present study aimed to investigate the effect and possible mechanism of recombinant human thrombopoietin (rhTPO) on mouse 32D cells (a mouse myeloid progenitor cell line) treated with serum from patients with aplastic anemia and to elucidate the ...
Juan Qian +7 more
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Aplastic anemia in China [PDF]
Abstract Aplastic anemia (AA) is a hematologic disease characterized by pancytopenia. Up to now, severe aplastic anemia (SAA) has been recognized by international and domestic scholars as an autoimmune disease with bone marrow (BM) failure mediated by the hyperfunctional T lymphocytes.
Liu, Chunyan, Shao, Zonghong
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Profil Penderita Anemia Aplastik di RSUP Dr. M. Djamil Padang Tahun 2018-2019
Background. Aplastic anemia is a failure of the process of formation and development of blood cells that causes a decrease or absence of hematopoietic precursor cells in the bone marrow.
Amanda Rizki +2 more
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The Monocytopenia of Aplastic Anemia [PDF]
Abstract Eight out of 22 patients with aplastic anemia died from infections. All five patients with fewer than 100 granulocytes and 20 monocytes per cu mm of blood succumbed to overwhelming sepsis. The relationship that existed between absolute granulocyte and monocyte counts made it impossible to determine whether neutropenia or ...
J J, Twomey, C C, Douglass, O, Sharkey
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Aplastic anemia is a rare but potentially life-threatening disease that may affect older patients. Data regarding the treatment of aplastic anemia in this ageing population remains scarce.
Adrien Contejean +22 more
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