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Approach to the diagnosis of aplastic anemia.
Establishing a diagnosis of aplastic anemia (AA) can be challenging, but it is absolutely critical to appropriate management, especially differentiating between acquired and inherited forms of the disease. The hematology field requires updated diagnostic
A. Dezern, J. Churpek
semanticscholar +1 more source
Predicting response of severe aplastic anemia to immunosuppression combined with eltrombopag
Pretreatment blood counts, particularly an absolute reticulocyte count ≥25×109/L, correlate with response to immunosuppressive therapy in severe aplastic anemia.
Yoshitaka Zaimoku +6 more
semanticscholar +1 more source
Most acquired aplastic anemia is the result of immune-mediated destruction of hematopoietic stem cells causing pancytopenia and an empty bone marrow, which can be successfully treated with either immunosuppressive therapy or hematopoietic stem-cell transplantation.In aplastic anemia, oligoclonally expanded cytotoxic T cells induce apoptosis of ...
Neal S, Young +2 more
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The North American Pediatric Aplastic Anemia Consortium (NAPAAC) is a group of pediatric hematologist‐oncologists, hematopathologists, and bone marrow transplant physicians from 46 institutions in North America with interest and expertise in aplastic ...
K. Shimano +25 more
semanticscholar +1 more source
Aplastic Anemia Treated with Eltrombopag during Pregnancy
Aplastic anemia is a rare blood disorder characterized by pancytopenia and hypocellular bone marrow. In patients with aplastic anemia, pancytopenia sometimes worsens during pregnancy, and relapse of aplastic anemia in pregnancy is common.
Yuri Suminaga +7 more
doaj +1 more source
Aplastic anemia is rare hematological disorder with approximate incidence 1.5-7 cases per million individuals per year. Osteonecrosis, a frequently seen in patients with aplastic anemia.
Shalvi Mahajan +3 more
doaj +1 more source
Introduction Aplastic anemia is a rare and potentially life-threatening hematological disorder with incidence of 1.4 to 14 cases/million. It is associated with exposures to certain environmental chemicals, drugs and infections.
Muhammad Asif Syed +3 more
semanticscholar +1 more source
Treatments of aplastic anemia are comprised of supportive therapy and aplastic anemia-specific therapy aimed at restoring hematopoiesis. Supportive therapies include transfusion, G-CSF, and the administration of iron chelation agents, as well as dealing ...
K. Usuki
semanticscholar +1 more source
The present study aimed to investigate the effect and possible mechanism of recombinant human thrombopoietin (rhTPO) on mouse 32D cells (a mouse myeloid progenitor cell line) treated with serum from patients with aplastic anemia and to elucidate the ...
Juan Qian +7 more
doaj +1 more source
Aplastic anemia in China [PDF]
Abstract Aplastic anemia (AA) is a hematologic disease characterized by pancytopenia. Up to now, severe aplastic anemia (SAA) has been recognized by international and domestic scholars as an autoimmune disease with bone marrow (BM) failure mediated by the hyperfunctional T lymphocytes.
Liu, Chunyan, Shao, Zonghong
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