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Pathogenesis of aplastic anemia [PDF]

Hematology, 2019
Aplastic anemia (AA) is a rare and life-threatening bone marrow failure (BMF) that results in peripheral blood cytopenia and reduced bone marrow hematopoietic cell proliferation. The symptoms are similar to myelofibrosis, myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) making diagnosis of AA complicated.
Li, Wang, Hong, Liu
openaire   +2 more sources

Incidence and risk factors of aplastic anemia in Latin American countries: the LATIN case-control study

Haematologica, 2009
Background Associations between aplastic anemia and numerous drugs, pesticides and chemicals have been reported. However, at least 50% of the etiology of aplastic anemia remains unexplained.Design and Methods This was a case-control, multicenter ...
Eliane Maluf, Nelson Hamerschlak, Alexandre Biasi Cavalcanti, Álvaro Avezum Júnior, José Eluf-Neto, Roberto Passetto Falcão, Irene G. Lorand-Metze, Daniel Goldenberg, Cézar Leite Santana, Daniela de Oliveira Werneck Rodrigues, Leny Nascimento da Motta Passos, Luis Gastão Mange Rosenfeld, Marimilia Pitta, Sandra Loggetto, Andreza A. Feitosa Ribeiro, Elvira Deolinda Velloso, Andrea Tiemi Kondo, Erika Oliveira de Miranda Coelho, Maria Carolina Tostes Pintão, Hélio Moraes de Souza, José Rafael Borbolla, Ricardo Pasquini   +21 more
doaj   +1 more source

Aplastic Anemia in Pregnancy [PDF]

The Journal of Obstetrics and Gynecology of India, 2013
Although aplastic anemia was first recognized by Ehrlich in 1888, the pathogenesis of aplastic anemia has remained elusive. The prevalence of aplastic anemia in pregnancy is rare. Aplastic anemia is a subtype of anemia characterized by pancytopenia and a hypocellular bone marrow.
Swati, Rathore, Angsumita, Pramanick, Annie, Regi, Jessie, Lionel   +3 more
openaire   +2 more sources

Successful treatment of severe aplastic anemia with syngeneic stem cell transplantation in the setting of active disseminated mucormycosis

Medical Mycology Case Reports, 2019
Severe aplastic anemia (SAA) is a hematological disease resulting in pancytopenia due to bone marrow failure. Treatment consists of immunosppressive therapy, or allo-SCT.
Jean El-Cheikh, Ali Atoui, Nour Moukalled, Nohra Ghaoui, Haidar El Darsa, Souha S. Kanj, Ali Bazarbachi   +6 more
doaj   +1 more source

Aplastic Anemia in a Developing Country: The Present and the Need [PDF]

National Journal of Laboratory Medicine, 2016
Introduction: Aplastic anemia (AA) a rare, yet a life threatening hematological disorder. Aplastic anemia if untreated results in very high mortality. Early diagnosis of Aplastic anemias is essential for appropriate management of the patient.
Ashwini BR , Seetu Palo, Siddiq M Ahmed
doaj   +1 more source

Circulating thrombopoietin levels in normal healthy blood donors and in aplastic anemia patients in relation to disease severity

Asian Journal of Transfusion Science, 2015
Background: Thrombopoietin (TPO) is the key hematopoietic growth factor regulating the production of platelets from bone marrow megakaryocytes and maintaining platelet hemostasis.
Abhay Singh, Anupam Verma, Soniya Nityanand, Rajendra Chaudhary, Priti Elhence   +4 more
doaj   +1 more source

Proposed protocol for treatment of severe periodontitis without platelet transfusion in patients with aplastic anemia: a case report

Journal of Medical Case Reports, 2021
Background Aplastic anemia is an intractable disease characterized by pancytopenia, susceptibility to infection, and difficulty in achieving hemostasis.
Satoru Morikawa, Kazuya Watanabe, Satoshi Usuda, Yoko Miyashita, Taneaki Nakagawa   +4 more
doaj   +1 more source

A plasma microRNA signature as a biomarker for acquired aplastic anemia

Haematologica, 2017
Aplastic anemia is an acquired bone marrow failure characterized by marrow hypoplasia, a paucity of hematopoietic stem and progenitor cells, and pancytopenia of the peripheral blood, due to immune attack on the bone marrow.
Kohei Hosokawa, Sachiko Kajigaya, Xingmin Feng, Marie J. Desierto, Maria del Pilar Fernandez Ibanez, Olga Rios, Barbara Weinstein, Phillip Scheinberg, Danielle M. Townsley, Neal S. Young   +9 more
doaj   +1 more source

Aplastic anemia associated to systemic lupus erythematosus in an AIDS patient: a case report

Revista Brasileira de Hematologia e Hemoterapia, 2013
Aplastic anemia is a bone marrow failure syndrome characterized by peripheral cytopenias and hypocellular bone marrow. Although aplastic anemia is idiopathic in most cases, rheumatic diseases such as systemic lupus erythematosus are recognized as causes ...
Leonardo Rodrigues de Oliveira, Thais Camargos Ferreira, Fernando de Freitas Neves, Antonio Carlos de Oliveira Meneses   +3 more
doaj   +1 more source

Severe retinal hemorrhages at various levels with a serous retinal detachment in a pediatric patient with aplastic anemia–A case report

Frontiers in Medicine, 2023
BackgroundAplastic anemia can cause ophthalmic abnormalities in patients. Vision loss in a child with aplastic anemia due to massive retinal hemorrhages at various levels is rare.Case presentationA pediatric patient with aplastic anemia presented with ...
Xiaoshuang Jiang, Mengxi Shen, Licong Liang, Philip J. Rosenfeld, Fang Lu   +4 more
doaj   +1 more source