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Severe aplastic anemia (SAA) is a hematological disease resulting in pancytopenia due to bone marrow failure. Treatment consists of immunosppressive therapy, or allo-SCT.
Jean El-Cheikh+6 more
doaj +1 more source
Preleukemia: hematological disorders prior to onset of leukemia [PDF]
Published data on Japanese leukemia patients with a preleukemic hematological disorder were assessed. The reexamined cases were from the "Japona Centra Revuo Medicina" reported during the period from 1952 to 1971.
Hiraki, Kiyoshi+5 more
core +1 more source
Aplastic Anemia in Pregnancy [PDF]
Although aplastic anemia was first recognized by Ehrlich in 1888, the pathogenesis of aplastic anemia has remained elusive. The prevalence of aplastic anemia in pregnancy is rare. Aplastic anemia is a subtype of anemia characterized by pancytopenia and a hypocellular bone marrow.
Annie Regi+3 more
openaire +3 more sources
Background: Thrombopoietin (TPO) is the key hematopoietic growth factor regulating the production of platelets from bone marrow megakaryocytes and maintaining platelet hemostasis.
Abhay Singh+4 more
doaj +1 more source
Steroid induced osteonecrosis: An analysis of steroid dosing risk. [PDF]
Osteonecrosis is a serious condition involving bone destruction that frequently requires surgical treatment to rebuild the joint. While there is an abundance of literature documenting corticosteroid related osteonecrosis, there is no consensus as to the ...
Chang, Christopher+4 more
core +1 more source
The Monocytopenia of Aplastic Anemia [PDF]
Abstract Eight out of 22 patients with aplastic anemia died from infections. All five patients with fewer than 100 granulocytes and 20 monocytes per cu mm of blood succumbed to overwhelming sepsis. The relationship that existed between absolute granulocyte and monocyte counts made it impossible to determine whether neutropenia or ...
O. Sharkey+2 more
openaire +3 more sources
Aplastic Anemia Complicating Orthotopic Liver Transplantation for Non-A, Non-B Hepatitis [PDF]
Aplastic anemia developed in 9 of 32 patients (28 percent) undergoing orthotopic liver transplantation for acute non-A, non-B hepatitis, at one to seven weeks after the procedure.
A.G. Tzakis+32 more
core +1 more source
Background Aplastic anemia is an intractable disease characterized by pancytopenia, susceptibility to infection, and difficulty in achieving hemostasis.
Satoru Morikawa+4 more
doaj +1 more source
A plasma microRNA signature as a biomarker for acquired aplastic anemia
Aplastic anemia is an acquired bone marrow failure characterized by marrow hypoplasia, a paucity of hematopoietic stem and progenitor cells, and pancytopenia of the peripheral blood, due to immune attack on the bone marrow.
Kohei Hosokawa+9 more
doaj +1 more source
Invasive bacterial infections in Gambians with sickle cell anaemia in an era of widespread Pneumococcal and Haemophilus influenzae type B vaccination [PDF]
Background: There is relatively little data on the aetiology of bacterial infections in patients with sickle cell anaemia (SCA) in West Africa, and no data from countries that have implemented conjugate vaccines against both Streptococcus pneumoniae and ...
Anderson, ST+5 more
core +1 more source