Results 41 to 49 of about 1,301 (49)

THPO gene variants in patients with acquired aplastic anemia

Hematology, Transfusion and Cell Therapy, 2018
Background: Human aplastic anemia is a hematologic disease characterized by low peripheral blood cell counts associated with reduced numbers of hematopoietic stem and progenitor cells and a hypocellular bone marrow.
Pedro Henrique Padilha, Gustavo Borges, Barbara Amélia Santana, Larissa Alessandra Medeiros, Samir Kanaan Nabhan, Ricardo Pasquini, Flavia Sacilotto Donaires, Rodrigo Tocantins Calado   +7 more
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Exome sequencing identifies MPL as a causative gene in familial aplastic anemia

Haematologica, 2012
The primary cause of aplastic anemia remains unknown in many patients. The aim of this study was to clarify the genetic cause of familial aplastic anemia.
Amanda J. Walne, Arran Dokal, Vincent Plagnol, Richard Beswick, Michael Kirwan, Josu de la Fuente, Tom Vulliamy, Inderjeet Dokal   +7 more
doaj   +1 more source

Nivolumab Induced Lethal Aplastic Anemia in a Patient with Metastatic Melanoma

Case Reports in Oncology, 2019
Nivolumab is an active treatment in patients with metastatic melanoma. We report a case of a patient with metastatic malignant melanoma who was given nivolumab as an advanced-line treatment.
Keren Rouvinov, Karen Nalbandyan, Victor Kozlov, Nir Peled, Alexander Yakobson   +4 more
doaj   +1 more source

Acquired hemoglobin H disease in a patient with aplastic anemia evolving into acute myeloid leukemia

São Paulo Medical Journal
CONTEXT: The prognosis of severe aplastic anemia has improved since the introduction of bone marrow transplantation and treatment with antithymocyte globulin.
Maria Stella Figueiredo, Perla Vicari, Eliza Yuriko Sugano Kimura, Sandra Vallin Antunes, Mihoko Yamamoto   +4 more
doaj   +1 more source

Cutaneous Finding in Anti Thymocyte Globulin Induced Serum Sickness

Iranian Journal of Allergy, Asthma and Immunology, 2006
Polyclonal anti-thymocyte globulin (ATG) is used as an immunosuppressive agent in the treatment of aplastic anemia (AA). Serum sickness is a recognized side effect of ATG.
Seyed Hesamedin Nabavizadeh, Mehran Karimi, Reza Amin   +2 more
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Incidence of aplastic anemia and agranulocytosis in Latin America: the LATIN study

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Aplastic anemia and agranulocytosis are rare but life-threatening disorders, often caused by drugs and other environmental exposures.
Nelson Hamerschlak, Eliane Maluf, Ricardo Pasquini, José Eluf-Neto, Frederico Rafael Moreira, Alexandre Biasi Cavalcanti, Íria Ruriko Okano, Roberto Passeto Falcão, Marimília Teixeira Pita, Sandra Regina Loggetto, Luiz Gastão Rosenfeld, Irene Gyongyvér Heidemarie Lorand-Metze   +11 more
doaj   +1 more source

Recurrent idiopathic acute hepatitis-associated aplastic anemia/pancytopenia fourteen years after initial episode

Annals of Hepatology, 2010
Aplastic anemia following viral hepatitis is a condition well recognized in the medical literature. Although hepatitis-associated aplastic anemia is an uncommon syndrome, there are several reports in the literature describing such cases. In these reports,
Nawal Al Nahdi, Holly Wiesinger, Heather Sutherland, Eric M. Yoshida   +3 more
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Aplastic anemia secondary to adjuvant Osimertinib therapy: a case report and a review of literature

Frontiers in Oncology
Aplastic anemia is a rare hematological disorder characterized by suppressed hematopoiesis and pancytopenia. Although several drugs have been associated with aplastic anemia, its occurrence in response to Osimertinib, a third-generation epidermal growth ...
Ahmed Abdalhadi, Nabil E. Omar, Nabil E. Omar, Samah Kohla, Samah Kohla, Hassan Aakel, Yeslem Ekeibed, Reyad Mohsen   +7 more
doaj   +1 more source

Severe aplastic anemia: allogeneic bone marrow transplantation as first-line treatment

Blood Advances, 2018
: Treatment of severe aplastic anemia has improved significantly over the past 4 decades. This review will summarize the key areas of progress in the use of allogeneic hematopoietic cell transplantation and nontransplant immunosuppressive therapy (IST ...
George E. Georges, Kris Doney, Rainer Storb   +2 more
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