Results 41 to 50 of about 156,004 (159)

Charting Morphotoxicity With Complementary Embryo Models

Advanced Healthcare Materials, Volume 15, Issue 35, 18 September 2026.
Three human embryo models of the peri‐implantation stages are exposed to a library of compounds. The (toxic) effects of the compounds are analyzed through automated image analysis pipelines. By evaluating the differential responses of the embryo models, this study underscores the importance of testing complementary embryo models to achieve robust and ...
Dorian G. Luijkx, Pauline L. Balder, Romy M. L. Verhagen, Vinidhra Shankar, Barry Jutten, Pinak Samal, Timo Rademakers, Clemens A. van Blitterswijk, Stefan Giselbrecht, Erik J. Vrij   +9 more
wiley   +1 more source

Thiamine-responsive megaloblastic anemia syndrome

, 2010
Thiamine-responsive megaloblastic anemia (TRMA) syndrome usually associated with diabetes mellitus, anemia and deafness, due to mutations in SLC19A2, encoding a thiamine transporter protein. The onset of disease is usually seen during infancy or at early
Hizli, Samil, KESKİN, MEHMET, Samil Hizli, Mehmet Keskin, Alper Dai, Fatma Gumruk, Uygun, Hatice, Dai, Alper, Hatice Uygun, GÜMRÜK, FATMA, Ali Bay, Bay, Ali   +11 more
core   +1 more source

Inherited microcytic anemias due to disorders of iron and heme metabolism: An updated clinical review

HemaSphere, Volume 10, Issue 9, September 2026.
Abstract Microcytic anemia is among the most common hematological abnormalities in clinical practice and is usually attributable to iron deficiency, thalassemia traits, or anemia of inflammation. A small but clinically important subset of patients, however, has inherited disorders of iron metabolism or heme synthesis presenting with persistent ...
Alexandros Makis, Ioanna Saougou, Eleftheria Hatzimichael   +2 more
wiley   +1 more source

The Intake of Junk Food as an Etiological Factor of Megaloblastic Anemia in Patients visiting Mayo Hospital, Lahore

Journal of University College of Medicine and Dentistry, 2023
Objective: The study was performed to determine role of junk food intake in the development of megaloblastic anemia. Methodology: It was a clinical based cross-sectional study conducted at Mayo Hospital Lahore in collaboration with Pathology ...
Zunairah Mughal, Dr, Hira Babar, Raana Akhtar, Dr, Ambareen Hamid, Dr, Sobia Ashraf, Dr, Samina Qamar, Dr   +5 more
doaj   +1 more source

PPI Misuse in Bangladesh: Confronting a Silent Epidemic Through Deprescribing and Regulatory Reform—A Policy Perspective

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Proton pump inhibitors (PPIs) are subject to rampant global misuse, posing a significant public health challenge. This issue is particularly acute in low‐ and middle‐income countries like Bangladesh, where preliminary data indicate alarmingly high rates of inappropriate prescribing, driven by systemic factors within the ...
Abdullaha Al Mamun, Md Rabiul Awual, K. A. M. Inzamul Islam   +2 more
wiley   +1 more source

Mechanistic Insights Into Hepatotoxicity‐Induced Liver Cirrhosis and Anemia: Iron Dysregulation, the Hepcidin–Ferroportin Axis, and Emerging Therapeutic Strategies

Organ Medicine, Volume 3, Issue 3, Page 171-185, September 2026.
Patients with alcohol‐associated liver cirrhosis or acetaminophen (APAP) toxicity frequently develop anemia with iron metabolism disturbances. Dysregulation of hepcidin–ferroportin signaling, along with inflammation, oxidative stress, hypoxia, impaired intestinal iron absorption, malnutrition, and gastrointestinal bleeding, contributes to anemia ...
Debabrata Dash, Raj Kumar Koiri
wiley   +1 more source

Pulmonary embolism and megaloblastic anemia: is there a link? A case report an literature review

Radiology Case Reports, 2018
Many factors have been associated with venous thromboembolism. Among them, vitamin B12 deficiency can produce elevated homocysteine levels, which is a risk factor for venous embolism, since the latter interferes with the activation of Va coagulation ...
Grecia Iveth Raymundo-Martínez, MD, Rodrigo Gopar-Nieto, MD, Gonzalo Carazo-Vargas, MD, Diego Araiza-Garaygordobil, MD, Sergio Raul Scuri, MD, Laura Leticia Rodríguez-Chavez, MD, Nilda Espinola-Zavaleta, MD, PhD   +6 more
doaj   +1 more source

Megaloblastic Anemia in Bardet-Biedl Syndrome: A Rare Case Report

Clinical Medicine Insights: Case Reports, 2023
Background: Bardet-Biedl syndrome (BBS) also known as Laurence-Moon-Bardet-Biedl syndrome one of the rarely reported genetic disorder characterized by an intellectual disability, limb, kidney abnormalities, obesity, and Rod-cone dystrophy.
Subtain Hassan, Qaisar Ali Khan, Priyadharshini Saravanan, Sumaira Iram, Samia Rohail, Naod F Belay, Muhammad Afzal, Faiza Amatul Hadi, Harshawardhan Pande   +8 more
doaj   +1 more source

Perioperative Transfusion Trigger Score Versus Restrictive Transfusion in Older Non‐Cardiac Surgery Patients: A Multicenter Randomized Controlled Trial

Journal of the American Geriatrics Society, Volume 74, Issue 9, Page 2564-2572, September 2026.
ABSTRACT Background Restrictive transfusion (Hb < 7 g/dL) is recommended for most perioperative patients, but the optimal threshold for those with cardiovascular disease or Hb 7–10 g/dL remains uncertain. The Perioperative Transfusion Trigger Score (POTTS), which integrates adrenaline requirement, FiO2, temperature, and angina history, may standardize ...
Shucong Liang, Lijuan Bai, Guizhen Yang, Zhuo Chen, Yujia Wei, Yanxia Wei, Yuting Lv, Zehan Huang, Yanjuan Huang, Kejian Lu   +9 more
wiley   +1 more source

Comparative Assessment of Vitamin-B12, Folic Acid and Homocysteine Levels in Relation to p53 Expression in Megaloblastic Anemia. [PDF]

PLoS ONE, 2016
Megaloblastic anemia (MBA), also known as macrocytic anemia, is a type of anemia characterized by decreased number of RBCs as well as the presence of unusually large, abnormal and poorly developed erythrocytes (megaloblasts), which fail to enter blood ...
Manish K Yadav, Nandini M Manoli, SubbaRao V Madhunapantula   +2 more
doaj   +1 more source