Studies on the Hemoglobin of Cooley's Anemia and Cooley's Trait [PDF]
The diseases sickle cell anemia and Cooley's anemia (also known as thalassemia or Mediterranean anemia) have associated with them "minor" or "trait" forms of the disease in which the symptomatology is minimal, and the abnormalities in the red cells are ...
Rich, Alexander
core
Comorbidities in aging patients with sickle cell disease. [PDF]
Sickle cell disease (SCD) in general and sickle cell anemia in particular is a highly complex disorder both at the molecular and clinical levels. Although the molecular lesion is a single-point mutation, the sickle gene is pleiotropic in nature causing ...
Ballas, Samir K.
core +2 more sources
Barriers to Pediatric Sickle Cell Disease Guideline Recommendations. [PDF]
National guidelines recommend that providers counsel all patients with sickle cell anemia about hydroxyurea (HU) therapy and screen children with sickle cell anemia annually for the risk of stroke with transcranial Doppler (TCD).
Bardach, Naomi S+6 more
core
Surgery in sickle cell anemia [PDF]
Sickle cell anemia is a hemoglobin disorder with a wide range of clinical manifestations and complications. Medical treatment is the mainstay of management but surgery is indicated in some cases. The authors review the main surgical indications in sickle
Chiabi, AT, Fokam, P
core +1 more source
Interview with Albertha Cook [PDF]
In her August 1984 interview with Michael Cooke, Albertha Cook discussed her time at the Committee on Better Racial Assurance (COBRA) and the organization’s association with DHEC.
Cook, Albertha
core +1 more source
The Virginia Sickle Cell Anemia Awareness Program: Education, Screening, and Counseling [PDF]
In 1968, a program of screening for sickle trait carriers was begun as part of the work of the Hematology Division, Department of Medicine, at the Medical College of Virginia.
Cooper, Florence N., Scott, Robert B.
core +1 more source
Appraisal of patient-reported outcome measures in analogous diseases and recommendations for use in phase II and III clinical trials of pyruvate kinase deficiency [PDF]
Purpose: Pyruvate kinase deficiency (PKD) is a rare disease and understanding of its epidemiology and associated burden remains limited. With no current curative therapy, clinical manifestations can be life threatening, clinically managed by maintaining ...
Ionova, Tatyana+3 more
core +1 more source
Medicinal Cannabis Use in Sickle Cell Anemia [PDF]
Approximately 100,000 Americans suffer from sickle cell anemia (SCA), a severe hereditary form of anemia in which red blood cells can mutate into a sickled shape causing severe pain crises that can lead to ED visits, hospitalization, and negatively ...
Axelrod, MD, JD, David+3 more
core +1 more source
The Evolving Pharmacotherapeutic Landscape for the Treatment of Sickle Cell Disease. [PDF]
Sickle cell disease (SCD) is an extremely heterogeneous disease that has been associated with global morbidity and early mortality. More effective and inexpensive therapies are needed.
Ballas, Samir K
core +1 more source
Lack of mortality in 22 children with sickle cell anemia and severe malarial anemia [PDF]
Retrospective studies suggest that there is high mortality in children with sickle cell anemia (SCA) and severe malaria. We assessed mortality in Ugandan children with severe malarial anemia (SMA, n = 232) or cerebral malaria (CM, n = 267) by sickle cell
Bangirana, Paul+5 more
core +1 more source