Results 191 to 200 of about 35,287 (246)
Some of the next articles are maybe not open access.
Journal of the American Medical Association, 1950
The purpose of this report is to emphasize the possibility of the occasional early onset of sickle cell anemia and to consider it in the differential diagnosis of jaundice during the neonatal period in the Negro. Sickle cell anemia 1 is a hereditary and congenital disease of the hemopoietic system occurring almost entirely in members of the Negro race.
C A, FRAZIER, C E, RICE
openaire +2 more sources
The purpose of this report is to emphasize the possibility of the occasional early onset of sickle cell anemia and to consider it in the differential diagnosis of jaundice during the neonatal period in the Negro. Sickle cell anemia 1 is a hereditary and congenital disease of the hemopoietic system occurring almost entirely in members of the Negro race.
C A, FRAZIER, C E, RICE
openaire +2 more sources
Journal of Theoretical Biology, 1977
Abstract A number of metabolites have recently been investigated to determine whether or not they can prevent or reverse the sickling of red blood cells which contain the abnormal hemoglobin, hemoglobin S, of sickle cell anemia (SCA). An hypothesis is suggested in which one of these compounds, urea, may play a significant role in the precipitation of
Kirt J. Vener, Donald M. Perrill
openaire +2 more sources
Abstract A number of metabolites have recently been investigated to determine whether or not they can prevent or reverse the sickling of red blood cells which contain the abnormal hemoglobin, hemoglobin S, of sickle cell anemia (SCA). An hypothesis is suggested in which one of these compounds, urea, may play a significant role in the precipitation of
Kirt J. Vener, Donald M. Perrill
openaire +2 more sources
THE ADOLESCENT WITH SICKLE CELL ANEMIA
Hematology/Oncology Clinics of North America, 1996Adolescence is a time of intense change and turmoil. Helping patients with sickle cell disease have a smooth transition from the pediatric to adult health care environment is an important and meaningful experience. Facilitating the patient's transition, however, takes time and effort.
T R, Kinney, R E, Ware
openaire +2 more sources
Cholestasis in sickle cell anemia
The American Journal of Medicine, 1964Abstract A patient with sickle cell anemia who presented with marked cholestatic jaundice is described, with emphasis upon the difficulties encountered in differentiating this symptom complex from extrahepatic obstruction due to stone formation. This patient had extraordinarily high serum bilirubin levels, apparently the result of increased bilirubin ...
F M, KLION, M J, WEINER, F, SCHAFFNER
openaire +2 more sources
PATHOPHYSIOLOGY OF SICKLE CELL ANEMIA
Hematology/Oncology Clinics of North America, 1996The anemia results from the markedly shortened circulatory survival of SS cells, together with a limited erythropoietic response. Both independent properties of Hb S-polymerization of the deoxy-Hb and instability of the oxy-Hb-contribute to early red cell destruction by effects on the Hb and on the red cell membranes.
R M, Bookchin, V L, Lew
openaire +2 more sources
Archives of Pediatrics & Adolescent Medicine, 1958
Sickling can be produced in the blood of young Negro babies with sickle-cell trait. The percentage of cells showing this change is low but will increase as the infant matures. The homozygous state is present from birth; however, recognition of the symptomatic condition is rare in infants under the age of 4 months.
S L, LEIKIN, J W, McCOO
openaire +2 more sources
Sickling can be produced in the blood of young Negro babies with sickle-cell trait. The percentage of cells showing this change is low but will increase as the infant matures. The homozygous state is present from birth; however, recognition of the symptomatic condition is rare in infants under the age of 4 months.
S L, LEIKIN, J W, McCOO
openaire +2 more sources
The electrocardiogram in sickle-cell anemia
American Heart Journal, 1955Abstract 1. 1. Sixty random patients with a hematologic diagnosis of sickle-cell anemia have been studied for clinical and electrocardiographic evidence of heart disease. 2. 2. The various types of electrocardiographic abnormalities have been discussed and compared with those found in the literature.
C L, LINDO, L R, DOCTOR
openaire +2 more sources
Hypersplenism in Sickle Cell Anemia
Archives of Internal Medicine, 1964Although splenomegaly in children with sickle cell anemia is common, massive enlargement associated with thrombocytopenia and very severe anemia is rare. In such patients, splenectomy has been followed by increase in platelet count and hemoglobin concentration. This suggests that an acquired hypersplenism aggravated the hemolytic process.
E C, ROSSI +3 more
openaire +2 more sources
The Treatment of Sickle Cell Anemia
Archives of Internal Medicine, 1974"Sickle cell crisis" is a diagnosis made by exclusion, and infection must be ruled out as a cause of symptoms whenever a patient becomes acutely ill. Partial exchange transfusion is an important therapeutic tool, for it seems to interrupt "the vicious cycle of sickling" in some instances and forestall it in others.
openaire +2 more sources
Sickle Cell Anemia and Hearing
Annals of Otology, Rhinology & Laryngology, 1980The present investigation examined the effects of sickle cell anemia on threshold hearing. The study included 43 homozygous sickle cell anemia patients, ages 7–18 years, and 23 age-matched controls with documented normal hemoglobin. Both the study and control groups received otologic and audiologic examinations.
E M, Friedman +3 more
openaire +2 more sources