Results 21 to 30 of about 205,200 (274)

Comorbidities in aging patients with sickle cell disease. [PDF]

open access: yes, 2018
Sickle cell disease (SCD) in general and sickle cell anemia in particular is a highly complex disorder both at the molecular and clinical levels. Although the molecular lesion is a single-point mutation, the sickle gene is pleiotropic in nature causing ...
Ballas, Samir K.
core   +2 more sources

Enhancing sickle cell anemia/sickle cell disease genetic understanding through simulation: A descriptive pilot study

open access: yes, 2015
Objective : Post-test pilot descriptive study of the genetic component of a simulation scenario addressing sickle cell anemia/sickle cell disease exploring students’ and nurse educators’ perceived genetic knowledge.
L. Sharoff
semanticscholar   +1 more source

Hematologic and hemorheological determinants of resting and exercise-induced hemoglobin oxygen desaturation in children with sickle cell disease

open access: yesHaematologica, 2013
The aim of the study was to determine the factors associated with resting and exercise-induced hemoglobin oxygen desaturation. The well-established six-minute walk test was conducted in 107 sickle cell children (50 with sickle hemoglobin C disease and 57
Xavier Waltz   +12 more
doaj   +1 more source

Nutritional status, hospitalization and mortality among patients with sickle cell anemia in Tanzania

open access: yesHaematologica, 2011
Background Reduced growth is common in children with sickle cell anemia, but few data exist on associations with long-term clinical course. Our objective was to determine the prevalence of malnutrition at enrolment into a hospital-based cohort and ...
Sharon E. Cox   +8 more
doaj   +1 more source

Hydroxyurea for Children with Sickle Cell Anemia in Sub‐Saharan Africa

open access: yesNew England Journal of Medicine, 2019
BACKGROUND Hydroxyurea is an effective treatment for sickle cell anemia, but few studies have been conducted in sub‐Saharan Africa, where the burden is greatest.
L. Tshilolo   +10 more
semanticscholar   +1 more source

Association between sickle cell and β-thalassemia genes and hemoglobin concentration and anemia in children and non-pregnant women in Sierra Leone: ancillary analysis of data from Sierra Leone’s 2013 National Micronutrient Survey

open access: yesBMC Research Notes, 2018
Objective By measuring the associations between the presence of sickle cell and β-thalassemia genes, we assessed the extent to which these hemoglobinopathies contribute to the high prevalence of anemia observed in preschool-aged children and women of ...
James P. Wirth   +4 more
doaj   +1 more source

Prevalence of sickle cell disease and sickle cell trait in national neonatal screening studies

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2011
Sickle cell anemia is the best known hereditary blood disorder; there are serious complications associated with the condition. Diagnosis and early intervention reduce morbidity and mortality.
Luciana Garcia Lervolino   +5 more
doaj   +1 more source

Fatal Dengue in Patients with Sickle Cell Disease or Sickle Cell Anemia in Curaçao: Two Case Reports [PDF]

open access: yes, 2013
Fatal Dengue in Patients with Sickle Cell Disease or Sickle Cell Anemia in Curaçao: Two Case ...
ACE Andrianarisoa   +17 more
core   +6 more sources

Sickle cell anemia

open access: yesNursing Made Incredibly Easy!, 2020
Genes are translated into proteins; mutations often (but not always) result in changes in the sequence of amino acids in those proteins. Changes in the amino acid sequence can modify (in various ways) or even completely destroy protein function. Proteins
Derek Hayse
semanticscholar   +1 more source

Saudi SCD patients’ symptoms and quality of life relative to the number of ED visits [PDF]

open access: yes, 2016
Background Individuals living with sickle cell disease (SCD) have significantly increased emergency department (ED) use compared to the general population. In Saudi Arabia, health care is free for all individuals and therefore has no bearing on increased
Ahmed, Anwar E.   +6 more
core   +2 more sources

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