Results 31 to 40 of about 34,389 (155)

Hemorheological risk factors of acute chest syndrome and painful vaso-occlusive crisis in children with sickle cell disease

Haematologica, 2012
Background Little is known about the effects of blood rheology on the occurrence of acute chest syndrome and painful vaso-occlusive crises in children with sickle cell anemia and hemoglobin SC disease.Design and Methods To address this issue, steady ...
Yann Lamarre, Marc Romana, Xavier Waltz, Marie-Laure Lalanne-Mistrih, Benoît Tressières, Lydia Divialle-Doumdo, Marie-Dominique Hardy-Dessources, Jens Vent-Schmidt, Marie Petras, Cedric Broquere, Frederic Maillard, Vanessa Tarer, Maryse Etienne-Julan, Philippe Connes   +13 more
doaj   +1 more source

Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population [PDF]

Genetics and Molecular Biology, 2020
Fetal hemoglobin (HbF) is a determining factor for the development of sickle cell anemia. High HbF levels lower the intensity of symptoms of this disease. HbF levels can vary in patients with sickle cell anemia and individuals without the disease.
Cristian Fong, Yesica Mendoza, Guillermo Barreto   +2 more
doaj   +1 more source

Hematological and hemorheological determinants of the six-minute walk test performance in children with sickle cell anemia. [PDF]

PLoS ONE, 2013
The six-minute walk test is a well-established submaximal exercise reflecting the functional status and the clinical severity of sickle cell patients. The aim of the present cross-sectional study was to investigate the biological determinants of the six ...
Xavier Waltz, Marc Romana, Marie-Dominique Hardy-Dessources, Yann Lamarre, Lydia Divialle-Doumdo, Marie Petras, Vanessa Tarer, Régine Hierso, Kizzy-Clara Baltyde, Benoît Tressières, Marie-Laure Lalanne-Mistrih, Fréderic Maillard, Olivier Hue, Maryse Etienne-Julan, Philippe Connes   +14 more
doaj   +1 more source

Haptoglobin gene polymorphisms and interleukin-6 and -8 levels in patients with sickle cell anemia

Revista Brasileira de Hematologia e Hemoterapia, 2015
BACKGROUND: Haptoglobin genotypes, and interleukin-6 and -8 participate in the pathophysiology of sickle cell anemia. The expression of cytokines is regulated by genetic mechanisms however the effect of haptoglobin polymorphisms on these cytokines is not
Bruna Spinella Pierrot-Gallo, Perla Vicari, Sandra Satiko Matsuda, Samuel Ademola Adegoke, Grazielle Mecabo, Maria Stella Figueiredo   +5 more
doaj   +1 more source

Relationship between pulmonary and cardiac abnormalities in sickle cell disease: implications for the management of patients

Revista Brasileira de Hematologia e Hemoterapia, 2016
Objective: To evaluate the association between clinical, pulmonary, and cardiovascular findings in patients with sickle cell disease and, secondarily, to compare these findings between sickle cell anemia patients and those with other sickle cell diseases.
Maria Christina Paixão Maioli, Andrea Ribeiro Soares, Ricardo Bedirian, Ursula David Alves, Cirlene de Lima Marinho, Agnaldo José Lopes   +5 more
doaj   +1 more source

Coexistent sickle cell anemia and autoimmune hemolytic anemia in two adolescents [PDF]

Einstein (São Paulo)
The development of alloantibodies or autoantibodies is a complication observed in sickle cell disease. Autoimmunization occurs in 7.6-12% of chronically or intermittently transfused patients with sickle cell disease; however, the clinical implications of
Vinícius Reis Soares, Bruna Paccola Blanco, Carla Luana Dinardo, Marlene Pereira Garanito   +3 more
doaj   +1 more source

Hemoglobin E Disorders in South Gujarat – A Study Of 35 Cases

National Journal of Community Medicine, 2012
Background:Among the inherited disorders of blood, hemoglobinopathies and thalassemia constitute a major bulk of non-communicable genetic disease in India.
B M Jha, Bhavna Gamit, Jitendra Patel, Kunal J Prajapati   +3 more
doaj  

Influence of ?S-globin haplotypes and hydroxyurea on tumor necrosis factor-alpha levels in sickle cell anemia

Revista Brasileira de Hematologia e Hemoterapia, 2014
Background: Sickle cell anemia is a chronic inflammatory disease characterized by an increased production of proinflammatory cytokines including tumor necrosis factor-alpha.
Marília Rocha Laurentino, Pedro Aurio Maia Filho, Maritza Cavalcante Barbosa, Izabel Cristina Justino Bandeira, Lilianne Brito da Silva Rocha, Romelia Pinheiro Gonçalves   +5 more
doaj   +1 more source

Liver Cirrhosis in a Patient with Sickle Cell Trait (Hb Sβ+ Thalassemia) without Other Known Causes of Hepatic Disease

Case Reports in Gastroenterology, 2009
Liver involvement in patients with sickle cell anemia/trait includes a wide range of alterations, from mild liver function test abnormalities to cirrhosis and acute liver failure. Approximately 15–30% of patients with sickle cell anemia present cirrhosis
Luca Santi, Giancarlo Montanari, Sonia Berardi, Corrado Patti, Marta Frigerio, Claudia Sama, Paolo Caraceni, Mauro Bernardi   +7 more
doaj   +1 more source

Sickle Cell Anemia Detection

, 2018
Anemia is a common name given to falls in oxygen transport capacity due to some of the functional disadvantages of red blood cells. Pathology Laboratorians put the tissue on the microscope glass and try to diagnose Anemia disease. Processes have been taken for a long time and it has been caused to distract.
Albayrak, Batuhan, Darıcı, Muazzez Buket, Kiracı, Furkan, Öğrenci, Arif Selçuk, Özmen, Atilla, Ertez, Kerem   +5 more
openaire   +4 more sources