Results 61 to 70 of about 205,200 (274)

Coexistent sickle cell anemia and autoimmune hemolytic anemia in two adolescents [PDF]

Einstein (São Paulo)
The development of alloantibodies or autoantibodies is a complication observed in sickle cell disease. Autoimmunization occurs in 7.6-12% of chronically or intermittently transfused patients with sickle cell disease; however, the clinical implications of
Vinícius Reis Soares, Bruna Paccola Blanco, Carla Luana Dinardo, Marlene Pereira Garanito   +3 more
doaj   +1 more source

Comorbidity, Pain, Utilization, and Psychosocial Outcomes in Older versus Younger Sickle Cell Adults: The PiSCES Project [PDF]

, 2017
Background. Patients with SCD now usually live well into adulthood. Whereas transitions into adulthood are now often studied, little is published about aging beyond the transition period. We therefore studied age-associated SCD differences in utilization,
Aisiku, Imoigele P., Bovbjerg, Viktor E., Levenson, James L., McClish, Donna K., Roberts, John D., Roseff, Susan D., Smith, Wally R.   +6 more
core   +4 more sources

A deep convolutional neural network for classification of red blood cells in sickle cell anemia

PLoS Comput. Biol., 2017
Sickle cell disease (SCD) is a hematological disorder leading to blood vessel occlusion accompanied by painful episodes and even death. Red blood cells (RBCs) of SCD patients have diverse shapes that reveal important biomechanical and bio-rheological ...
Mengjia Xu, Dimitrios P. Papageorgiou, Sabia Z. Abidi, M. Dao, Hong Zhao, G. Karniadakis   +5 more
semanticscholar   +1 more source

Phase 1 Study of the E-Selectin Inhibitor GMI 1070 in Patients with Sickle Cell Anemia [PDF]

, 2014
Background\ud \ud Sickle cell anemia is an inherited disorder of hemoglobin that leads to a variety of acute and chronic complications. Abnormal cellular adhesion, mediated in part by selectins, has been implicated in the pathophysiology of the vaso ...
Cheung, Anthony, DeCastro, Laura, Flanner, Henry, Kramer, William, Kuypers, Frans, Magnani, John L, Rhee, Seungshin, Styles, Lori, Telen, Marilyn J, Thackray, Helen, Wun, Ted   +10 more
core   +7 more sources

Análise do polimorfismo TA6/TA7 na região promotora do gene UGT1A1, em pacientes com anemia e traço falciforme de dois hospitais da cidade de Porto Alegre – RS [PDF]

, 2011
A doença de células falciformes é uma anemia hemolítica crônica de caráter autossômico recessivo, causada por uma mutação pontual no cromossomo 11. Esta mutação provoca a substituição de um ácido glutâmico por uma valina na posição seis da cadeia da ...
Antunes, Liana
core  

The clinical epidemiology of sickle cell anemia In Africa

American journal of hematology/oncology, 2017
Sickle cell anemia (SCA) is the commonest severe monogenic disorders of humans. The disease has been highly characterized in high‐income countries but not in sub‐Saharan Africa where SCA is most prevalent. We conducted a retrospective cohort study of all
A. Macharia, G. Mochamah, S. Uyoga, Carolyne M. Ndila, G. Nyutu, J. Makale, Metrine Tendwa, E. Nyatichi, J. Ojal, M. Shebe, Kennedy O. Awuondo, N. Mturi, N. Peshu, B. Tsofa, J. Scott, K. Maitland, T. Williams   +16 more
semanticscholar   +1 more source

Nutritional Potential, Phytochemical Content, In Vivo Antioxidant, and Antanemic Potential of Musa paradisiaca Flower

Food Chemistry International, EarlyView.
After collecting Musa paradisiaca leaves, some were dried and others were used to produce aqueous extracts. The extracts and powders were characterized and then administered to rats made anaemic by PHZ. After 14 days of administration of the two samples, the rats were euthanized and it was observed that after 9 days of treatment, the aqueous extract ...
Josée Rebeca Nombo, Jethro Roland Misse Ngangue Ekwala, Somon Régine Tuem, Stéphano Tene Tambo, Merlin Ngafon Nchoutpouen, Valery Jean François Nsoga, Jules Christophe Koule Manz, Jordan Mekui Nwotue, Mathieu Ndomou   +8 more
wiley   +1 more source

Hemoglobin E Disorders in South Gujarat – A Study Of 35 Cases

National Journal of Community Medicine, 2012
Background:Among the inherited disorders of blood, hemoglobinopathies and thalassemia constitute a major bulk of non-communicable genetic disease in India.
B M Jha, Bhavna Gamit, Jitendra Patel, Kunal J Prajapati   +3 more
doaj  

The impact of low‐dose aspirin on hemoglobin levels in pregnancy: A secondary analysis of a randomized controlled trial for prevention of hypertensive disorders of pregnancy

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objectives This study evaluates the association of low‐dose aspirin (LDA) with hemoglobin (Hb) levels during pregnancy and explores how changes in Hb levels relate to hypertensive disorders of pregnancy (HDP). Methods This secondary analysis of a randomized controlled trial comprised 249 pregnant women recruited from a regional hospital in ...
N. M. Ngcobo, V. Dorsamy, C. Bagwandeen, P. Z. Mkhize, J. Moodley   +4 more
wiley   +1 more source

Influence of ?S-globin haplotypes and hydroxyurea on tumor necrosis factor-alpha levels in sickle cell anemia

Revista Brasileira de Hematologia e Hemoterapia, 2014
Background: Sickle cell anemia is a chronic inflammatory disease characterized by an increased production of proinflammatory cytokines including tumor necrosis factor-alpha.
Marília Rocha Laurentino, Pedro Aurio Maia Filho, Maritza Cavalcante Barbosa, Izabel Cristina Justino Bandeira, Lilianne Brito da Silva Rocha, Romelia Pinheiro Gonçalves   +5 more
doaj   +1 more source