Results 161 to 170 of about 68,445 (312)
Establishment of rat model for aspiration pneumonia and potential mechanisms
Aspiration pneumonia was induced in Sprague Dawley rats by intratracheal instillation of hydrochloric acid (HCl, 1.5 μL/g.wt, pH = 1) followed by lipopolysaccharide (LPS, 20 μg/g.wt) after 1 h. The model reproduced hallmark features of acute lung injury, including histological lung damage, microvascular dysfunction, inflammation, hypoxemia, and ...
Hanbing Hu+7 more
wiley +1 more source
Cannabidiol (CBD) has numerous therapeutic properties, and is used to treat neurological conditions, such as neuroinflammation. However, the optimal dose of CBD to penetrate the brain requires further investigation. The primary aim of this study was to use a mouse model and the intrabuccal route for CBD administration to determine the optimal dose at ...
Oluwadara Pelumi Omotayo+4 more
wiley +1 more source
Possible Roles of Neural Electron Spin Networks in Memory and Consciousness [PDF]
Spin is the origin of quantum effects in both Bohm and Hestenes quantum formulism and a fundamental quantum process associated with the structure of space-time.
Hu, Huping, Wu, Maoxin
core +1 more source
Unilateral, minimally invasive, renal arterial embolization and delayed contralateral nephrectomy was described in cats as a novel remnant kidney model of chronic kidney disease using two doses of embolic particles. Renal function declined and characteristic histopathological markers of kidney disease were present 6 months after the embolism procedure.
Chad W. Schmiedt+7 more
wiley +1 more source
Though the Leprdb/db mouse is a common and well‐studied model of type II diabetes mellitus, there are a few specific guidelines for its husbandry, and wound complications are common. We present a modified husbandry approach for the Leprdb/db mouse that includes increased cage size, decreased housing density, and more frequent cage changes.
May Barakat+6 more
wiley +1 more source
This study details the adaptations required to establish a long‐term anesthetic protocol in pigs. Three protocols were evaluated, with some causing malignant hyperthermia, hypoglycemia, or hemoynamic instability. The final protocol proved effective for developing a porcine AKI model requiring adequate arterial pressure maintenance.
Axel Guilpin+9 more
wiley +1 more source
We successfully constructed CAST/EiJ mice models infected with low‐dose vaccinia virus (VACV‐L), high‐dose VACV (VACV‐H), and mpox virus (MPXV), demonstrating that VACV‐L and MPXV infections induced splenomegaly in mice, and VACV‐H infection caused mortality in mice.
Yongzhi Hou+9 more
wiley +1 more source
Functionalizing biomedical implants with nanoparticle contrast agents introduces imaging capabilities to devices, improving patient care by avoiding inherent complications. However, nanoparticle surface chemistry optimized for device manufacturing may not lead to efficient nanoparticle clearance from tissues.
Kendell M. Pawelec+4 more
wiley +1 more source
International Forum of Allergy &Rhinology, Volume 15, Issue 5, Page 561-564, May 2025.
Adam J. Skelton+6 more
wiley +1 more source