Results 1 to 10 of about 58,579 (125)

Comparison of the efficacy of two doses of dexmedetomidine as an adjunct to levobupivacaine in infraclavicular brachial plexus block: prospective double-blinded randomized controlled trial

BMC Anesthesiology, 2022
Background This prospective, double-blind, randomized, controlled trial compared the efficacy of two dexmedetomidine doses (50 and 100-μg) combined with levobupivacaine on sensory block duration in infraclavicular brachial plexus block.
Huda F. Ghazaly, Ahmed Alsaied A. Aly, Zaher Zaki Zaher, Mahmoud M. Hassan, Ahmed Abdelreheem Mahmoud   +4 more
doaj   +1 more source

Isoflurane induces Art2‐Rsp5‐dependent endocytosis of Bap2 in yeast

FEBS Open Bio, 2021
Although general anesthesia is indispensable during modern surgical procedures, the mechanism by which inhalation anesthetics act on the synaptic membrane at the molecular and cellular level is largely unknown.
Fumi Kozu, Kanae Shirahama‐Noda, Yasuhiro Araki, Shintaro Kira, Hitoshi Niwa, Takeshi Noda   +5 more
doaj   +1 more source

Assessment of Three Anesthetics Used for Pulmonary Pharmacological Studies in Rats

Journal of Applied Veterinary Sciences, 2022
Experiments on pulmonary pharmacology are often performed in laboratory animals. Investigators collect organs, samples, or record modifications in the respiratory system during anaesthesia, which might significantly influence the data attained.
Gareeballah Osman Adam
doaj   +1 more source

Propofol EC50 for inducing loss of consciousness in patients under combined epidural-general anesthesia or general anesthesia alone: a randomized double-blind study

Frontiers in Medicine, 2023
BackgroundCombined epidural-general anesthesia (GA + EA) has been recommended as a preferred technique for both thoracic and abdominal surgery. The epidural anesthesia on the general anesthetic (GA) requirements has not been well investigated. Therefore,
Jiangling Wang, Jiangling Wang, Yajian Shen, Yajian Shen, Wenjing Guo, Wen Zhang, Xiaoying Cui, Shunv Cai, Xinzhong Chen   +8 more
doaj   +1 more source

Features and mechanisms of propofol-induced protein kinase C (PKC) translocation and activation in living cells

Frontiers in Pharmacology, 2023
Background and purpose: In this study, we aimed to elucidate the action mechanisms of propofol, particularly those underlying propofol-induced protein kinase C (PKC) translocation.Experimental approach: Various PKCs fused with green fluorescent protein ...
Soma Noguchi, Taketoshi Kajimoto, Takuya Kumamoto, Masashi Shingai, Soshi Narasaki, Soshi Narasaki, Tomoaki Urabe, Tomoaki Urabe, Serika Imamura, Kana Harada, Izumi Hide, Sigeru Tanaka, Yuhki Yanase, Shun-Ichi Nakamura, Yasuo M. Tsutsumi, Norio Sakai   +15 more
doaj   +1 more source

The Effects of Lemon Balm (Melissa officinalis L.) Essential Oil on the Stress Response, Anti-Oxidative Ability, and Kidney Metabolism of Sea Bass during Live Transport

Animals, 2022
This study was conducted to enhance the viability and alleviate the oxidative stress response using MO for sea bass during live transport. Six experimental groups were designed, and the effects of the physiological responses of MO were evaluated in ...
Qi Wang, Jun Mei, Jing Xie
doaj   +1 more source

The Use of Awake Videolaryngoscopy and an Innovative Flexible-Tipped Bougie in a Potentially Difficult Airway

Case Reports in Anesthesiology, 2020
We present a case where awake videolaryngoscopy (VL) was used, along with a flexible-tipped bougie to allow endotracheal intubation in a challenging airway. The patient presented for resection of a large left-sided parapharyngeal mass.
Will A. Watson, John Cormack
doaj   +1 more source

Smart needle electrical bioimpedance to provide information on needle tip relationship to target nerve prior to local anesthetic deposition in peripheral nerve block (USgPNB) procedures

Journal of Electrical Bioimpedance, 2023
Ultrasound guided peripheral nerve block (USgPNB) refers to anaesthetic techniques to deposit local anesthetic next to nerves, permitting painful surgery without necessitating general anesthesia.
Whelton Edel, Helen Lisa, O’Donnell Brian, O’Sullivan Martin, Ugwah Justina, Messina Walter, Wang Yineng, O’Mahoney Niamh, Moore Eric   +8 more
doaj   +1 more source

The validity of topical drug therapy for otitis media with effusion

Медицинский совет, 2021
Otitis media with effusion is difficult to diagnose, since the course of the disease is mostly asymptomatic, while the initial stage of the disease is very similar to Eustachiitis or the pre-perforative stage of acute otitis media.
S. V. Morozova, K. V. Eremeeva, W. H.A. Suaifan   +2 more
doaj   +1 more source

Mechanistic insights into volatile anesthetic modulation of K2P channels

eLife, 2020
K2P potassium channels are known to be modulated by volatile anesthetic (VA) drugs and play important roles in clinically relevant effects that accompany general anesthesia.
Aboubacar Wague, Thomas T Joseph, Kellie A Woll, Weiming Bu, Kiran A Vaidya, Natarajan V Bhanu, Benjamin A Garcia, Crina M Nimigean, Roderic G Eckenhoff, Paul M Riegelhaupt   +9 more
doaj   +1 more source