Semaglutide to remodel mitochondrial dynamics and mitophagy balance for vascular dementia therapy
The effects of semaglutide on IR, mitochondrial dynamics, and mitophagy in the hippocampus of BCAS mice after CCH. It was shown that semaglutide maintained the balance of mitochondrial dynamics and mitophagy by improving IR and passing through GLP‐1R/PI3K/Akt pathway, reduced hippocampal neuroinflammation and neuron loss, and thus promoted the recovery
Xiaoyan Yang+11 more
wiley +1 more source
Effect of remimazolam tosilate for injection (HR7056) versus sevoflurane on the incidence of postoperative delirium in older patients undergoing total hip arthroplasty: study protocol for a prospective, multicentre, two-arm, parallel-group, randomised controlled trial. [PDF]
Wang LY, Zhang MQ, Sun R, Li L, Li DL.
europepmc +1 more source
Insights on caesarean section in the southern tamandua (Tamandua tetradactyla)
Abstract An adult female southern tamandua (Tamandua tetradactyla) was rescued and taken to a veterinary centre for wildlife care. The patient's evaluation revealed an abnormal neurological status, along with prostration, diarrhoea, dehydration and bilateral corneal ulcers. Insecticide poisoning (carbamate, organophosphate or organochlorine) and canine
Diego Rodrigues Gomes+4 more
wiley +1 more source
Reporting practices of anesthetic and analgesic use in rodent orthopedic research. [PDF]
Pan Y, Cohen S.
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ABSTRACT Spasmodic dysphonia is a laryngeal dystonia that can present as adductor, abductor, or mixed types, with or without tremor. The etiology is not understood fully. Comprehensive evaluation is required to establish the diagnosis. Treatments include voice therapy, medications, botulinum toxin injection, laryngeal surgery, deep brain stimulation ...
Aaron J. Jaworek, Robert T. Sataloff
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Cannabinoids and General Anesthetics: Revisiting Molecular Mechanisms of Their Pharmacological Interactions. [PDF]
Echeverria-Villalobos M+6 more
europepmc +1 more source
Management of Vocal Fold Leukoplakia
ABSTRACT Vocal fold leukoplakia (VFL) is a descriptive term for a white plaque in the true vocal folds (TVF). It is estimated at 10.2 cases per 100,000 males and 2.1 per 100,000 females. The most critical aspect of managing a VLF is achieving an accurate pathological diagnosis, since a white plaque in the TVF can have numerous differential diagnoses ...
Isabela H. Schettini, Thomas L. Carroll
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The relationship between anesthesia, surgery and postoperative immune function in cancer patients: a review. [PDF]
Guo R+7 more
europepmc +1 more source
ABSTRACT The ongoing invasion of the zoonotic parasite Angiostrongylus cantonensis threatens humans, other mammals, and birds. In Mallorca, neurological disorders associated with this parasite are increasingly reported in free‐living Algerian hedgehogs, Atelerix algirus, raising public health concerns.
Anna Šipková+7 more
wiley +1 more source