Results 221 to 230 of about 17,361 (286)

"Nebulized lidocaine for intractable cough in hospice care: a comprehensive review of efficacy, safety, and future perspectives". [PDF]

BMC Palliat Care
Pan J, Khan AA, Yu W, Rui L.
europepmc   +1 more source

Dietary Restriction Mitigates Vascular Aging, Modulates the cGAS‐STING Pathway and Reverses Macrophage‐Like VSMC Phenotypes in Progeroid DNA‐Repair‐Deficient Ercc1Δ/− Mice

Aging Cell, EarlyView.
Dietary restriction mitigates vascular aging in DNA‐repair‐deficient Ercc1Δ/− mice by reducing extracellular matrix remodeling, inflammation, oxidative stress, and switching of vascular smooth muscle cells to a macrophage‐like phenotype. Our findings suggest that the cGAS‐STING pathway plays a key role in vascular aging and that the benefits of dietary
S. J. M. Stefens, J. van der Linden, J. M. Heredia‐Genestar, R. M. C. Brandt, S. Barnhoorn, I. Nieuwenhuizen‐Bakker, N. van Vliet, J. H. M. Odijk, Y. Ridwan, D. Stuijts, M. Batenburg, J. H. J. Hoeijmakers, R. Kanaar, J. Essers, I. van der Pluijm   +14 more
wiley   +1 more source

Combined Effects of Mechanical Loading and Piezo1 Chemical Activation on 22‐Months‐Old Female Mouse Bone Adaptation

Aging Cell, EarlyView.
In vivo mechanical loading combined with Yoda2 injection produced an additive effect on cortical bone parameters in the tibiae of 22‐month‐old female mice. In vivo calcium signaling results suggest that Yoda2 could reach osteocytes and activate Piezo1.
Quentin A. Meslier, Robert Oehrlein, Sandra J. Shefelbine   +2 more
wiley   +1 more source

Inhalation anesthesia and total intravenous anesthesia (TIVA) regimens in patients with obesity: an updated systematic review and meta-analysis of randomized controlled trials. [PDF]

J Anesth Analg Crit Care
Domene SS, Fulginiti D, Thompson A, Vargas VPS, Rodriguez LC, Colón MDT, Madera MDF, Layton JN, Encarnación MIP, Arruarana VS, Cruz CS, Calderon-Martínez E.   +11 more
europepmc   +1 more source

Intermittent Supplementation With Fisetin Improves Physical Function and Decreases Cellular Senescence in Skeletal Muscle With Aging: A Comparison to Genetic Clearance of Senescent Cells and Synthetic Senolytic Approaches

Aging Cell, EarlyView.
Supplementation with the natural senolytic agent fisetin attenuated age‐related declines in physical function in mice. Better physical function with fisetin was accompanied by lower expression of cell senescence‐related genes. Fisetin treatment had comparable effects on physical function as genetic clearance of senescent cells and synthetic senolytic ...
Kevin O. Murray, Sophia A. Mahoney, Katelyn R. Ludwig, Jill H. Miyamoto‐Ditmon, Nicholas S. VanDongen, Nirad Banskota, Allison B. Herman, Douglas R. Seals, Robert T. Mankowski, Matthew J. Rossman, Zachary S. Clayton   +10 more
wiley   +1 more source

N-Acety-L-Cysteine Alleviates Isoflurane-Triggered Neuronal Cell Parthanatos by Suppressing Reactive Oxygen Species Accumulation Through the Induction of c-Jun N-Terminal Kinase Signaling Pathway Inhibition. [PDF]

J Biochem Mol Toxicol
Liu N, Liu Y, Wang X, Liu M, Wang Y, Feng C, Piao M.   +6 more
europepmc   +1 more source

Rare but relevant: Hydrocarbons and sudden sniffing syndrome

Addiction, EarlyView.
Abstract Inhaled hydrocarbon‐associated sudden collapse (IHASC), often referred to as ‘sudden sniffing death syndrome’ is a critical and often fatal event linked to the inhalation of volatile hydrocarbons, primarily occurring in adolescents and young adults. This syndrome manifests as sudden cardiac and/or respiratory arrest, typically occurring during
Ingrid Berling, Geoffrey Kennedy Isbister   +1 more
wiley   +1 more source

Postoperative analgesia in patients undergoing thoracotomy: A comparison between total intravenous anesthesia and inhalation anesthesia. [PDF]

Pak J Med Sci
Lee JY, Jeong ST, Hwang JH, Park SH.
europepmc   +1 more source

Asthma Alleviation by Ginsenoside Rb1 via Promotion of Treg Proliferation and Inflammatory T Cell Inhibition

Allergy, EarlyView.
Screening of 250 natural products identified ginsenoside Rb1 (gRb1) as a potent modulator of regulatory T cells (Tregs) and inflammatory T cells. gRb1 increased IL‐10‐ and TGF‐β‐expressing Tregs while reducing Th17, Th1, and Th2 populations in both asthma model mice and human PBMCs.
Susanna Choi, Seung‐Ah Yoo, Kon‐Young Ji, Dong Ho Jung, Saseong Lee, Kang‐Gu Lee, Ki‐Myo Kim, Joo Young Lee, Myung‐A Jung, Bo‐Jeong Pyun, Jung Hur, Joon Young Choi, Chin Kook Rhee, Wan‐Uk Kim, Taesoo Kim   +14 more
wiley   +1 more source

Ultrasound-guided supraclavicular brachial plexus block as an additive to sevoflurane anesthesia in pediatrics undergoing brachiobasilic arteriovenous fistula operation: randomized controlled clinical trial. [PDF]

BMC Anesthesiol
Elsawy S, Fathy E, Elbadawy A, Elnaggar A, Abdelatif AF, Elmorabaa H, Hamed R.   +6 more
europepmc   +1 more source