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The pharmacology of inhaled anesthetics
Seminars in Anesthesia, Perioperative Medicine and Pain, 2005The two most popular potent inhaled anesthetics, desflurane and sevoflurane, differ in pharmacological advantages and disadvantages in sometimes subtle and sometimes obvious ways. Sevoflurane has a low solubility and absent pungency that makes it easy to use and is the anesthetic of choice for an inhalational induction of anesthesia.
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Inhaled anesthetics: an historical overview
Best Practice & Research Clinical Anaesthesiology, 2005Inhalational agents have played a pivotal role in anesthesia history. The first publicly demonstrated anesthetic of the modern era, diethyl ether, was an inhalational anesthetic. The attributes of a good agent, ability to rapidly induce anesthesia, with limited side effects has led research efforts for over a hundred and fifty years.
Francis X. Whalen+2 more
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Pharmacology of Inhalational Anesthetics
2010Learn the pharmacokinetic factors affecting the rate of induction and emergence with inhalational anesthetics Understand the concept of Minimum Alveolar Concentration (MAC) Know the key characteristics of the four most commonly used inhalational agents (nitrous oxide, isoflurane, desflurane, sevoflurane)
Jerome M. Adams, John W. Wolfe
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Safety of Intravenous and Inhalation Anesthetics
20139.2 Determination of Safety of Inhalation Anesthetics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 279 9.2.1 General Considerations . . . . . . . . . . . . . . . . . . . . . . . . . . . . 279 9.2.2 Safety Margin of Inhalation Anesthetics . . . . . . . . . .
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A History of Inhaled Anesthetics [PDF]
Valerius Cordus synthesized diethyl ether in 1540 and shortly thereafter Theophrastus Bombastus von Hohenheim (Paracelsus) noted that it could diminish pain. Priestley synthesized nitrous oxide in 1774, and in 1800, Davy found that it decreased pain and suggested its use for surgery.
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