Results 71 to 80 of about 736,541 (316)

Intravenous anesthetics have differential effects on human potassium channels

Acta Biochimica et Biophysica Sinica
General anesthetics are widely used in the clinic and greatly promote the development of surgery. However, the incidence of cardiovascular and respiratory complications caused by general anesthetics is still high, and the underlying mechanisms remain ...
Tao Ying, Yao Kejie, Wu Jing, Xu Tian, Lin Junhui, Qin Yi, Su Diansan, Cai Shiqing, Yu Weifeng, Chen Xuemei   +9 more
doaj   +1 more source

Efeitos do propofol sobre o sistema de condução cardíaca Efectos del propofol sobre el sistema de conducción cardíaco Effects of propofol on the cardiac conduction system

Revista Brasileira de Anestesiologia, 2010
JUSTIFICATIVA E OBJETIVOS: Alguns estudos têm demonstrado que o uso do propofol é, algumas vezes, associado a bradiarritmias ou reversão de arritmias para ritmo sinusal.
Paulo Warpechowski, Ari Tadeu Lírio dos Santos, Paulo José Irigon Pereira, Gustavo Glotz de Lima   +3 more
doaj   +1 more source

Volatile anesthetics isoflurane and sevoflurane directly target and attenuate Toll‐like receptor 4 system

The FASEB Journal, 2019
General anesthesia has been the requisite component of surgical procedures for over 150 yr. Although immunomodulatory effects of volatile anesthetics have been growingly appreciated, the molecular mechanism has not been understood.
T. Okuno, S. Koutsogiannaki, Lifei Hou, W. Bu, U. Ohto, R. Eckenhoff, T. Yokomizo, Koichi Yuki   +7 more
semanticscholar   +1 more source

Ovarian Function Restoration with Biomimetic Scaffold Incorporating Angiogenic Molecules and Antioxidant in Chemotherapy‐Induced Perimenopausal Model

Advanced Healthcare Materials, EarlyView.
This study developed a biomimetic scaffold incorporating PDRN and melatonin to restore ovarian function in chemotherapy‐induced premature ovarian insufficiency, enhancing cell survival, folliculogenesis, and hormone normalization, while improving fertility rates and offspring in a mouse model, offering a promising strategy for ovarian function ...
Da‐Seul Kim, Dong Seok Jeong, So‐Yeon Park, Ji‐Won Jung, Jeoung Eun Lee, Jun‐Kyu Lee, Seung‐Woon Baek, Dong Ryul Lee, Dong Keun Han   +8 more
wiley   +1 more source

Characterization of brain-wide somatosensory BOLD fMRI in mice under dexmedetomidine/isoflurane and ketamine/xylazine

Scientific Reports, 2021
Mouse fMRI under anesthesia has become increasingly popular due to improvement in obtaining brain-wide BOLD response. Medetomidine with isoflurane has become well-accepted for resting-state fMRI, but whether this combination allows for stable, expected ...
Taeyi You, Geun Ho Im, Seong-Gi Kim
doaj   +1 more source

Effects of propofol-based total intravenous anesthesia on gastric cancer: a retrospective study

OncoTargets and Therapy, 2018
Background Several kinds of cancer surgeries with propofol-based total intravenous anesthesia (TIVA) have been shown to have better outcomes than those with sevoflurane-based inhalational anesthesia (INHA).
Xiaoyu Zheng, Yu Wang, Linlin Dong, Su Zhao, Liping Wang, Hong Chen, Yang Xu, Guonian Wang   +7 more
semanticscholar   +1 more source

Ischemic Myocardium Targeting Peptide‐Guided Nanobubbles for Multimodal Imaging and Treatment of Coronary Microvascular Dysfunction

Advanced Healthcare Materials, EarlyView.
Nanobubbles functionalized with indocyanine green and ischemic myocardium‐targeting peptide effectively target cardiomyocytes and enable the multimodal (fluorescence, ultrasonic, and photoacoustic) imaging of ischemic myocardium in mice with coronary microvascular dysfunction (CMD).
Bo Yu, Ziwei Pang, Jing Zhao, Jingyi Xue, Hsuan Lo, Tiancheng Gu, Ping Zhang, Jiawei Tian, Guo‐Qing Du   +8 more
wiley   +1 more source

Combined implanted central venous access and cortical recording electrode array in freely behaving mice

MethodsX, 2021
Establishing a long-lasting, functioning venous access in a non-anesthetized mouse is very challenging at least. Since we needed a reliable venous access to titrate intravenous anesthetics, we refined and combined previously described methods.
David Peter Obert, David Killing, Tom Happe, Alp Altunkaya, Gerhard Schneider, Matthias Kreuzer, Thomas Fenzl   +6 more
doaj  

Injection pain of propofol in children: A comparison of two formulations without added lidocaine

Journal of Anaesthesiology Clinical Pharmacology, 2012
Background: Propofol emulsion in medium and long-chain triglycerides (MCT/LCT) has been reported to cause less injection pain than other propofol solutions in adult studies.
Serbülent Gökhan Beyaz, Ali Eman
doaj   +1 more source

Effects of Intravenous Anesthetics on Renal Ischemia/Reperfusion Injury

Renal Failure, 2009
Background. Renal ischemia/reperfusion (I/R)-induced tubular epithelial cell injury, called ischemic acute renal failure, is associated with high mortality in humans.
Husamettin Yuzer, M. F. Yuzbasioglu, H. Çıralık, E. Kurutaş, O. Ozkan, E. Bulbuloglu, Y. Atlı, O. Erdogan, I. T. Kale   +8 more
semanticscholar   +1 more source