Results 111 to 120 of about 89,380 (260)
Arthritis Care &Research, EarlyView.Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer +4 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source
Discordance Between Patient and Physician Global Assessments in Early Systemic Sclerosis
Arthritis Care &Research, EarlyView.Objective This study aims to identify factors associated with patient global assessment (PtGA) and physician global assessment (PhGA) and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (<5 years) from the Collaborative National Quality and Efficacy Registry were included.
Ellen Romich +35 more
wiley +1 more source
Sodium channels as targets for volatile anesthetics
, 2012 The molecular mechanisms of modern inhaled anesthetics although widely used in clinical settings are still poorly understood. Considerable evidence supports effects on membrane proteins such as ligand- and voltage-gated ion channels of excitable cells ...
Karl F. Herold +2 more
core +1 more source
Clinical, Histologic, and Serological Predictors of Renal Function Loss in Lupus Nephritis
Arthritis Care &Research, EarlyView.Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang +21 more
wiley +1 more source
Mode of action of local anesthetics
, 1968 A review is given in which the following topics were discussed: the ion canal as site of action of local anesthetics, effect of local anesthetics on the stimulation of nerves, binding of local anesthetics (ephedrine derivs.), and activity studies with ...
Schönenberger, Helmut +2 more
core
Non anesthetic action of local anesthetics [PDF]
, 2013 Local anesthetics are not only used as drugs to block the sodium channel to provide analgesi and anti-arrhythmic action. The purpose of this review is to highlight the new indications and limitations of this class of drugs. Recent research has focused on
ALAIN BORGEAT, BORGEAT, ALAIN
core +1 more source
Current Medical IssuesBackground: Multimodal regimens are the mainstay of postoperative analgesia. Analgesic effectiveness of programmed intermittent bolus (PIB) versus continuous infusion (CI) in ultrasound-guided adductor canal block (ACB) for unilateral knee arthroplasty ...
Anu Krupa Thomas +6 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang +10 more
wiley +1 more source
Frontiers in MedicineBackgroundHepatectomy, a commonly employed surgical approach for treating liver-related disorders, has emerged as the primary method for the radical treatment of early stage liver cancer.
Shaojuan Wang +6 more
doaj +1 more source