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THE ADMINISTRATION OF ANESTHETICS. [PDF]
JAMA: The Journal of the American Medical Association, 1898 A man who desires to study medicine can find many places in Chicago where they will undertake to teach him, but I do not know of any place where they will teach him to administer anesthetics. There are many places where he may learn but no place where any provision is made for properly teaching the subject. The student is not left to his own resources
D. H. GALLOWAY
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Proteomic Learning of Gamma-Aminobutyric Acid (GABA) Receptor-Mediated Anesthesia [PDF]
arXivAnesthetics are crucial in surgical procedures and therapeutic interventions, but they come with side effects and varying levels of effectiveness, calling for novel anesthetic agents that offer more precise and controllable effects. Targeting Gamma-aminobutyric acid (GABA) receptors, the primary inhibitory receptors in the central nervous system, could
Jiang J +7 more
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Amiodarone Provides Long-Lasting Local Anesthesia and Analgesia in Open-State Mouse Nociceptors
Frontiers in Pharmacology, 2022 Local anesthetics with long-lasting effects and selectivity for nociceptors have been sought over the past decades. In this study, we investigated whether amiodarone, a multiple channel blocker, provides long-lasting local anesthesia and whether adding a
Masakazu Kotoda +6 more
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Physiological Reports, 2021 Some evidence suggests that both hypothermia and anesthesia can exert similar effects on metabolism and ventilation. This study examined the synergistic effects of anesthesia and hypothermia on ventilation in spontaneously breathing adult mice under ...
Saki Taiji +5 more
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Asian Journal of Medical Sciences, 2022 Background: Various adjuvants are added to local anesthetics to increase the duration of block during supraclavicular brachial plexus (SCBP) block.
Sangita Mandal +3 more
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Brain and Behavior, 2021 Introduction Recent animal studies showed that isoflurane exposure may lead to the disturbance of hippocampal neurogenesis and later cognitive impairment.
Xin‐Li Xiao +10 more
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The thermodynamics of general and local anesthesia [PDF]
Biophys. J. 2014, 106: 2143-2156, 2014 General anesthetics are known to cause depression of the freezing point of transitions in biomembranes. This is a consequence of ideal mixing of the anesthetic drugs in the membrane fluid phase and exclusion from the solid phase. Such a generic law provides physical justification of the famous Meyer-Overton rule.
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