Results 21 to 30 of about 310,289 (342)
Frontiers in Neurology, 2022 PurposeThis study aimed to explore the neurological effects of dexmedetomidine-induced sedation on memory using functional stability, a whole-brain voxel-wise dynamic functional connectivity approach.MethodsA total of 16 participants (10 men) underwent ...
Lin-Lin Liu +11 more
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Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation. [PDF]
, 2014 BackgroundMany anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABAA) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar
Brosnan, Robert J, Pham, Trung L
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F1000Research, 2015 An interesting and valuable discussion has arisen from our recent article (Segerdahl, Mezue et al., 2015) and we are pleased here to have the opportunity to expand on the various points we made.
Andrew R. Segerdahl +4 more
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New patents on topical anesthetics. [PDF]
, 2014 Anesthesia is defined as a total or partial loss of sensation and it may be general, local or topical, depending on the method of drug administration and area of the body affected.
CALVIERI, Stefano +6 more
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Journal of Anesthesia, 2019 General anesthetics are commonly used in major surgery. To achieve the depth of anesthesia for surgery, patients are being subjected to a variety of general anesthetics, alone or in combination.
Lingzhi Wu, Hailin Zhao, H. Weng, D. Ma
semanticscholar +1 more source
Combined Transcriptomics and Metabolomics Analyses in Grass Carp Under Anesthetic Stress
Frontiers in Cellular and Infection Microbiology, 2022 Ctenopharyngodon Idella, as a common freshwater bony fish, is more susceptible to various diseases than other carp species, so it has been proposed as a test organism for toxicological analysis In this study, C. idella were anesthetized with MS-222 and 2-
Tianwei Wang +14 more
doaj +1 more source
Effect of two-week continuous epidural administration of 2% lidocaine on mechanical allodynia induced by spinal nerve ligation in rats [PDF]
Anesthesia and Pain Medicine, 2020 Background Lidocaine is an effective against certain types of neuropathic pain. This study aimed to investigate whether timing of initiating continuous epidural infusion of lidocaine affected the glial activation and development of neuropathic pain ...
Yuseon Cheong +3 more
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Electrostatic Contributions of Aromatic Residues in the Local Anesthetic Receptor of Voltage-Gated Sodium Channels [PDF]
, 2008 Antiarrhythmics, anticonvulsants, and local anesthetics target voltage-gated sodium channels, decreasing excitability of nerve and muscle cells. Channel inhibition by members of this family of cationic, hydrophobic drugs relies on the presence of highly ...
Ahern, Christopher A. +3 more
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Adjuvants to local anesthetics: Current understanding and future trends
World Journal of Clinical Cases, 2017 Although beneficial in acute and chronic pain management, the use of local anaesthetics is limited by its duration of action and the dose dependent adverse effects on the cardiac and central nervous system.
A. Swain +3 more
semanticscholar +1 more source
Effects of local anesthetics on breast cancer cell viability and migration
BMC Cancer, 2018 Breast cancer accounts for nearly a quarter of all cancers in women worldwide, and more than 90% of women diagnosed with breast cancer undergo mastectomy or breast-conserving surgery.
Ru Li +5 more
semanticscholar +1 more source