Effect of two-week continuous epidural administration of 2% lidocaine on mechanical allodynia induced by spinal nerve ligation in rats [PDF]
Background Lidocaine is an effective against certain types of neuropathic pain. This study aimed to investigate whether timing of initiating continuous epidural infusion of lidocaine affected the glial activation and development of neuropathic pain ...
Yuseon Cheong +3 more
doaj +1 more source
Sympathomimetic anesthetics [PDF]
The characteristic anaesthetic and other pharmacological properties of phencyclidine, ketamine, dexoxadrol and etoxadrol and the structure-activity relationship of these compounds have been described. Their possible mode of action is discussed in reference to the central depressant actions of the sympathomimetic amines.
openaire +2 more sources
Transient neurologic symptoms following spinal anesthesia with isobaric mepivacaine: A decade of experience at Toronto Western Hospital [PDF]
Background: Transient neurologic symptoms (TNSs) can be distressing for patients and providers following uneventful spinal anesthesia. Spinal mepivacaine may be less commonly associated with TNS than lidocaine; however, reported rates of TNS with ...
Abdallah, Faraj W. +4 more
core +2 more sources
An interesting and valuable discussion has arisen from our recent article (Segerdahl, Mezue et al., 2015) and we are pleased here to have the opportunity to expand on the various points we made.
Andrew R. Segerdahl +4 more
doaj +1 more source
BackgroundThoraco-abdominal surgery cuts through muscle, disrupting the normal structure and function of the respiratory muscles, resulting in lower lung volumes and a higher risk of developing post-operative pulmonary complications (PPC). PPC remains an
Biruk Adie Admass +3 more
doaj +1 more source
Efficasy of different anesthetics for achieving deep sedation during magnetic resonance imaging in children: Anesthetics for a deep sedation during magnetic resonance imaging [PDF]
Introduction: During magnetic resonance imaging (MRI) in children, safe, fast and effective anesthetics should be chosen for achieving deep sedation. Until now, no single anesthetic had this qualities, and only with a combination of different anesthetics
Marjanović Vesna, Budić Ivana
doaj +1 more source
Desflurane Selectively Suppresses Long-latency Cortical Neuronal Response to Flash in the Rat [PDF]
Background—The effect of inhalational anesthetics on sensory-evoked unit activity in the cerebral cortex has been controversial. Desflurane has desirable properties for in vivo neurophysiologic studies but its effect on cortical neuronal activity and ...
Hudetz, Anthony G. +2 more
core +2 more sources
Comparison of infusion of Propofol and Isoflurane on blood glucose level during surgery in type 2 diabetic patient [PDF]
Background: Type 2 diabetes mellitus is a chronic metabolic disease, known as the most common type of diabetes and is associated with hyperglycemia, insulin resistance, and insulin-dependent infertility.
Mohammad Farzad Malekzadeh +1 more
doaj +1 more source
Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation. [PDF]
BackgroundMany anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABAA) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar
Brosnan, Robert J, Pham, Trung L
core +2 more sources
Anesthetic neurotoxicity in the developing brain: an update on the insights and implications for fetal surgery [PDF]
This review describes an in-depth analysis of the neurotoxicity associated with the anesthetic agents used during fetal surgery, intending to highlight the importance of understanding the effects of general anesthetics on the developing brain ...
Denise Cinquegrana +6 more
doaj +1 more source

