Results 91 to 100 of about 97,243 (292)
Embryo aneuploidy and ivf outcomes in patients with different spermatozoa aneuploidy rates
Our goal was to study the 13, 18, 21, X, Y chromosomes aneuploidy rate in the embryos of the couples with different spermatozoa aneuploidy rate.In prospective cohort study 56 infertile couples were divided into 3 groups by the spermatozoa aneuploidy rate
S A Sokur +4 more
doaj
WaveCNV: allele-specific copy number alterations in primary tumors and xenograft models from next-generation sequencing. [PDF]
MotivationCopy number variations (CNVs) are a major source of genomic variability and are especially significant in cancer. Until recently microarray technologies have been used to characterize CNVs in genomes.
Ali, Johar +11 more
core +3 more sources
Combination of aneuploidy and high S-phase fraction indicates increased risk of relapse in stage I endometrioid endometrial carcinoma [PDF]
Annika Patthey +5 more
openalex +1 more source
ABSTRACT Background Human papilloma virus (HPV) is a DNA virus capable of infecting mucous membranes. In most cases, the infection is cleared by the immune system, but a prolonged exposure to HPV can progress to cancer. 40%–60% of head and neck squamous cell carcinomas (HNSCC) are linked to HPV, which is considered a risk factor especially among young ...
Michela Bulfoni +12 more
wiley +1 more source
Aneuploidy in Early Miscarriage and its Related Factors
Background: Genetic factors are the main cause of early miscarriage. This study aimed to investigate aneuploidy in spontaneous abortion by fluorescence in situ hybridization (FISH) using probes for 13, 16, 18, 21, 22, X and Y chromosomes.
Chan-Wei Jia +10 more
doaj +1 more source
ABSTRACT Background Oral leukoplakia (OL) represents the most common oral potentially malignant disorder globally, with highly variable reported malignant transformation (MT) rates creating challenges for evidence‐based clinical management. Objective To systematically synthesize evidence on MT prevalence in OL and evaluate potential predictive ...
Mohammed Taib Fatih +13 more
wiley +1 more source
Populations of doubled haploids for genetic mapping in hexaploid winter triticale. [PDF]
To create a framework for genetic dissection of hexaploid triticale, six populations of doubled haploid (DH) lines were developed from pairwise hybrids of high-yielding winter triticale cultivars. The six populations comprise between 97 and 231 genotyped
Baenziger, PS +10 more
core +1 more source
New cell lines expanding the diversity of Ewing sarcoma models
What's New? A chromosomal translocation between the EWSR1 and ETS genes is the key oncogenic driver in Ewing sarcoma. EWSR1::FLI1, the most frequent fusion, is subdivided into different fusion types with unclear prognostic relevance. Here, the authors describe the establishment and characterization of four new, intrinsically immortal, patient‐derived ...
Maximilian Kerkhoff +13 more
wiley +1 more source
Mitochondria-encoded genes contribute to evolution of heat and cold tolerance in yeast [PDF]
Genetic analysis of phenotypic differences between species is typically limited to interfertile species. Here, we conducted a genome-wide noncomplementation screen to identify genes that contribute to a major difference in thermal growth profile between ...
Fay, Justin C +4 more
core +2 more sources
FIGO committee opinion: Environmental drivers of gynecologic and reproductive health
Abstract This FIGO committee opinion paper addresses the growing body of evidence linking environmental exposures to common gynecologic and reproductive conditions across the life course. From adolescence through menopause, women are exposed to a wide range of environmental toxicants, including endocrine‐disrupting chemicals, air pollutants, heavy ...
Nathaniel DeNicola +9 more
wiley +1 more source

