Results 41 to 50 of about 55,696 (242)

Impact of donor mare and stallion identity on the likelihood of pregnancy after transfer of in vitro produced embryos

Equine Veterinary Journal, EarlyView.
Abstract Background The success of in vitro embryo production (IVEP) is influenced by donor mare and stallion. Objectives To determine whether donor mare and stallion influence the pregnancy rate after transfer of in vitro produced (IVP) blastocysts and to identify factors influencing the likelihood of obtaining one or more pregnancies from a single ...
M. Papas, T. A. E. Stout, J. C. M. Vernooij, B. Leemans, L. Arnold, M. M. Beitsma, L. I. Wijnands, M. de Ruijter‐Villani, S. Colleoni, G. Lazzari, C. Galli, A. Claes   +11 more
wiley   +1 more source

Lymphocyte Micronucleus Formation Is Driven by Inflammation‐Induced Oxidative DNA Damage in Oesophageal Cancer Development

International Journal of Cancer, EarlyView.
Chromosomal instability is a hallmark of cancer, but minimally invasive ways to detect systemic DNA damage and cancer risk remain limited. Here, using patient blood samples, the authors investigated lymphocyte micronuclei (MN) frequency as a potential marker of DNA damage across the progression from gastroesophageal reflux disease to Barrett's ...
Kathryn Munn, Rachel Lawrence, Hasan Haboubi, Hamsa Naser, Kate Hurlow, Ume‐Kulsoom Shah, Lisa Williams, Sarah Gwynne, Owen Bodger, Jiri Zavadil, Francois Virard, Shareen Doak, Laura E. Thomas, Gareth Jenkins   +13 more
wiley   +1 more source

Optical Genome Mapping Reveals Frequent Cryptic Structural Aberrations in Normal Karyotype Acute Myeloid Leukemia

International Journal of Cancer, EarlyView.
Acute myeloid leukemia adult cases often appear cytogenetically normal when analyzed with conventional karyotyping. However, acquired structural variants may escape routine detection. Here, optical genome mapping detected diverse genomic alterations in nearly half of the analyzed cytogenetically normal cases.
Tuuni Turtinen, Andriana Valkama, Christopher Wray, Sandra Vorimo, Hannele Räsänen, Eeva‐Riitta Savolainen, Katri Pylkäs, Tuomo Mantere   +7 more
wiley   +1 more source

The Epigenetic Origin of Aneuploidy [PDF]

Current Genomics, 2008
Theodore Boveri, eminent German pathologist, observed aneuploidy in cancer cells more than a century ago and suggested that cancer cells derived from a single progenitor cell that acquires the potential for uncontrolled continuous proliferation. Currently, it is well known that aneuploidy is observed in virtually all cancers.
Herrera, Luis A, Prada, Diddier, Andonegui, Marco A, Dueñas-González, Alfonso   +3 more
openaire   +2 more sources

The association between male infertility and sperm disomy: Evidence for variation in disomy levels among individuals and a correlation between particular semen parameters and disomy of specific chromosome pairs

, 2004
BACKGROUND: The association between infertility and sperm disomy is well documented. Results vary but most report that men with severely compromised semen parameters have a significantly elevated proportion of disomic sperm.
Xiao P Zhai, Homa, ST, Christopikou Dimitra, Christopikou, D, Homa, Sheryl T., Zhai, Xiao-Ping, Tempest, Helen G., Dalakiouridou, Maria, Griffin Darren K, David Wright, Wright, David B., Darren K Griffin, Sheryl T Homa, Wright, D, Maria Dalakiouridou, Griffin, DK, Dimitra Christopikou, Wright David, Homa Sheryl T, Dalakiouridou Maria, Tempest Helen G, Tempest, HG, Helen G Tempest, Dalakiouridou, M, Zhai Xiao P, Zhai, XP, Christopikou, Dimitra, Griffin, Darren K.   +27 more
core   +1 more source

Optimizing outcomes in intrauterine insemination: A narrative synthesis of two decades of clinical research (2000–2024)

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Intrauterine insemination (IUI) is a widely used first‐line fertility treatment, yet its success rates vary considerably. This review synthesizes evidence from peer‐reviewed studies published between 2000 and 2024, including randomized controlled trials, cohort and case–control studies, as well as systematic and narrative reviews identified ...
Kasuni Akalanka
wiley   +1 more source

The association between sperm aneuploidy and male infertility: Screening, aetiology and possible routes to alternative therapy

, 2003
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.One in six couples wishing to start a family are infertile.
Tempest, Helen Ghislaine
core  

Determining parental origin of embryo aneuploidy: analysis of genetic error observed in 305 embryos derived from anonymous donor oocyte IVF cycles [PDF]

, 2014
Background: Since oocyte donors are typically young and believed to be a source of highly competent gametes, donor oocyte IVF is considered to be an effective treatment for diminished ovarian reserve.
Frederick, J.L., Khoury, C.D., Sills, E.S., Daniel A Potter, E Scott Sills, Charlotte D Khoury, Li, X., Potter, D.A., Xiang Li, Jane L Frederick   +9 more
core   +1 more source

Total cervical occlusion: A solution after cervico‐isthmic cerclage failure

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Spontaneous preterm birth is mainly caused by cervical incompetence. Cervical cerclage is the gold standard for preventing mid‐trimester losses and preterm deliveries. If cervical cerclage fails, cervico‐isthmic cerclage may be indicated.
Déborah Couet, Anne‐Gaëlle Pourcelot, Claire Szmulevicz, Perrine Capmas, Hervé Fernandez, Élodie Debras   +5 more
wiley   +1 more source

The muntjac spindle staining assay: An investigation of the ability of this assay to detect potential aneuploidy inducing agents

, 1988
This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.An assay using muntjac fibroblasts in conjunction with a differential spindle and chromosome stain was developed and evaluated for its ability to detect ...
Pascoe, Sally Ann
core