Determination of Five Coumarins in Angelicae Pubescentis Radix from Different Origins by HPTLC-Scanning [PDF]
Journal of Analytical Methods in Chemistry, 2022 The HPTLC method is widely used in the field of quality evaluation and component analysis of traditional Chinese medicine (TCM). This work developed an HPTLC method to determine the five effective components of osthole, columbianadin, isoimperatorin ...
Dangtong Ji +5 more
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Computation and molecular pharmacology to trace the anti-rheumatoid activity of Angelicae Pubescentis Radix [PDF]
BMC Complementary Medicine and Therapies, 2022 Background The mechanism of action of Angelicae Pubescentis Radix in rheumatoid arthritis treatment is complex; the pathways and protein targets involved remain unclear.
Junhao Zhang +7 more
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Traditional Chinese Medicine of Angelicae Pubescentis Radix: A Review of Phytochemistry, Pharmacology and Pharmacokinetics [PDF]
Frontiers in Pharmacology, 2020 Angelicae Pubescentis Radix (APR) is a widely used antirheumatic Chinese medicinal herb known as “Duhuo” in China. It has the effects of dispelling wind and removing dampness, diffusing impediment, and relieving pain, and is mainly indicated for ...
Yaqi Lu +8 more
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A Diol-Based-Matrix Solid-Phase Dispersion Method for the Simultaneous Extraction and Determination of 13 Compounds From Angelicae Pubescentis Radix by Ultra High-Performance Liquid Chromatography [PDF]
Frontiers in Pharmacology, 2019 A simple and eco-friendly Diol-based-matrix solid-phase dispersion method (MSPD) was optimized and established to simultaneously extract 13 bioactive compounds (7 coumarins and 6 phenolic acids) in Angelicae Pubescentis Radix (APR) by ultrahigh ...
Mingya Ding +12 more
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Distribution Assessments of Coumarins from Angelicae Pubescentis Radix in Rat Cerebrospinal Fluid and Brain by Liquid Chromatography Tandem Mass Spectrometry Analysis [PDF]
Molecules, 2018 Angelicae Pubescentis Radix (APR) is a widely-used traditional Chinese medicine. Pharmacological studies have begun to probe its biological activities on neurological disorders recently.
Yan-Fang Yang, Lei Zhang, Xiu-Wei Yang
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Transport of Twelve Coumarins from Angelicae Pubescentis Radix across a MDCK-pHaMDR Cell Monolayer—An in Vitro Model for Blood-Brain Barrier Permeability [PDF]
Molecules, 2015 Angelicae Pubescentis Radix (APR), a widely used traditional Chinese medicine, is reported to have central nervous system activities. The purpose of this study was to characterize the blood-brain barrier permeability of twelve coumarins from APR ...
Yan-Fang Yang +4 more
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Graphene Assisted in the Analysis of Coumarins in Angelicae Pubescentis Radix by Dispersive Liquid–Liquid Microextraction Combined with 1H-qNMR [PDF]
Molecules, 2021 The content of active components in traditional Chinese medicine is relatively small, and it is difficult to detect some trace components with modern analytical instruments, so good pretreatment and extraction are very important in the experiment ...
Yanmei Feng +3 more
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Separation and Enrichment of Three Coumarins from Angelicae Pubescentis Radix by Macroporous Resin with Preparative HPLC and Evaluation of Their Anti-Inflammatory Activity [PDF]
Molecules, 2019 In order to enrich and separate three coumarins (columbianetin acetate, osthole and columbianadin) from Angelicae Pubescentis Radix (APR), an efficient method was established by combining macroporous resins (MARs) with preparative high-performance liquid
Yuqiao Yang +6 more
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Angelicae Pubescentis Radix Remitted Intestine Damage in Mice Induced by Escherichia coli via Mediating Antioxidant Defense, Inflammatory Mediators, and Restoring Gut Microbiota [PDF]
Veterinary SciencesThis study aims to explore the therapeutic potential of Angelicae Pubescentis Radix (APR), a traditional Chinese medicine that is widely known for its anti-inflammatory, anti-oxidative, and anti-microbial properties, using a mouse model.
Kehong Deng +6 more
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Studies on Chemical Constituents of Radix Angelicae pubescentis [PDF]
E3S Web of Conferences, 2023 Backgound:Angelicae pubescentis is the root of Angelica pubescens Maxim. f. biserrata Shan et Yuan. The main active ingredients are coumarin and volatile oil, and it has a variety of pharmacological activities such as antibacterial, antioxidant and anti ...
Zhu Yan +3 more
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