Results 21 to 30 of about 529 (150)

Anti-Inflammatory Effect of Columbianadin against D-Galactose-Induced Liver Injury In Vivo via the JAK2/STAT3 and JAK2/p38/NF-κB Pathways [PDF]

Pharmaceuticals
Angelicae pubescentis radix (APR) has been traditionally used for thousands of years in China to treat rheumatoid arthritis (RA), an autoimmune disorder.
Zhe Ma, Lin Peng, Yaoyao Sheng, Wenhui Chu, Yongqian Fu   +4 more
doaj   +2 more sources

Clinical Efficacy and Safety of a Modified Moxibustion Therapy for Low Back Pain in Lumbar Disc Herniation: A Two-Center, Randomized, Controlled, Non-Inferiority Trial. [PDF]

J Pain Res
Kaiyang Xue,1 Xianzhu Wang,1 Caihong Xiao,2 Ning Zhang,1 Minghui Liu,3 Jing Fu,1 Jin Cui1 1College of Acupuncture and Massage, Guizhou University of Traditional Chinese Medicine, Guiyang, 550002, People’s Republic of China; 2Department of Acupuncture and
Xue K, Wang X, Xiao C, Zhang N, Liu M, Fu J, Cui J.   +6 more
europepmc   +3 more sources

Pharmacological and Pharmacokinetic Insights Into Columbianadin: A Promising Natural Anti-Inflammatory Compound. [PDF]

Mediators Inflamm
Columbianadin (CBN), a dihydroangelic acid ester and a naturally occurring coumarin compound, is primarily derived from plants in the Apiaceae family, notably the traditional Chinese medicinal herb Angelica pubescens. Modern pharmacological research has revealed that CBN exhibits a broad spectrum of bioactivities, including neuroprotective, antitumor ...
Wang Y, Tang L, Miao J, Cheng S, Xu Y, Xie W.   +5 more
europepmc   +2 more sources

Immunomodulatory Mechanisms of Rehmanniae Radix Praeparata-Achyranthes Root-Chinese Angelica Root Combination in Nontraumatic Osteonecrosis of the Femoral Head: A Comprehensive Network Pharmacology and Molecular Docking Study Focusing on Immunological Pathways. [PDF]

Mediators Inflamm
Objective Nontraumatic osteonecrosis of the femoral head (NONFH) is a devastating condition characterised by immune dysregulation and sterile inflammation, which are increasingly acknowledged as central pathogenic mechanisms. This study aims to identify the core herbal combination for NONFH and systematically explore its immunomodulatory effects and ...
Li X, Ng L, Liu C, Qin L, Xiao P, Liu C, Liu Y, Zhang Q, Huang W, Zhou Y.   +9 more
europepmc   +2 more sources

Simultaneous quantification and evaluate the differences of two skeleton components in raw, salt and wine Angelicae Pubescentis Radix by UPLC-MS/MS in negative/positive modes coupled with chemometrics

Journal of Future Foods, 2022
The aim of this study was to establish an ultra-performance liquid chromatography coupled with triple-quadrupole tandem mass spectrometry method with positive and negative ion exchange scanning mode for simultaneous quantification of two different ...
Lin Yang, Wanqing Zhang, Wen Deng, Hui Wang, Hongning Liu   +4 more
doaj   +1 more source

Transient Receptor Potential Channels as Key Regulators of Neuroinflammation in Neurological Disorders: Mechanistic Insights, Therapeutic Potentials, and Future Directions. [PDF]

CNS Neurosci Ther
This study elucidates the central role of transient receptor potential (TRP) channels in driving neuroinflammation across neurological disorders. Acting as critical molecular sensors on neurons and glial cells, TRP channels' activation initiates downstream pathways that promote the release of proinflammatory cytokines, a pathological mechanism in ...
Guo D, Cai M, Xian Y, Chen Y, Feng Y, Hu C, Zeng L, Shi L, Zhang S.   +8 more
europepmc   +2 more sources

The Efficacy and Safety of Chinese Herbal Medicine in the Treatment of Knee Osteoarthritis: An Updated Systematic Review and Meta-Analysis of 56 Randomized Controlled Trials. [PDF]

Oxid Med Cell Longev, 2022
Objective. This systematic review and meta‐analysis were performed to investigate the efficacy and safety of Chinese herbal medicine (CHM) in the treatment of knee osteoarthritis (KOA). Methods. An electronic search was conducted in eight databases (PubMed, EMBASE, Web of Science, Cochrane Library, Chinese National Knowledge Infrastructure, Chinese ...
Lin Z, Zheng J, Chen M, Chen J, Lin J.
europepmc   +2 more sources

Osthole Suppresses Knee Osteoarthritis Development by Enhancing Autophagy Activated via the AMPK/ULK1 Pathway

Molecules, 2022
Knee osteoarthritis (KOA) is an increasingly prevalent heterogeneous disease characterized by cartilage erosion and inflammation. As the main chemical constituent of Angelicae Pubescentis Radix (APR), an anti-inflammatory herbal medicine, the potential ...
Teng Ma, Xiangpeng Wang, Wenjing Qu, Lingsen Yang, Cheng Jing, Bingrui Zhu, Yongkui Zhang, Wenpeng Xie   +7 more
doaj   +1 more source

Tratamiento de síndrome de Löfgren de sarcoidosis con fórmula medicinal china basada en diferenciación de síndrome: una revisión basada en casos [PDF]

, 2023
Löfgren syndrome (LS) is a unique acute manifestation of sarcoidosis and characterized by erythema nodosum, bilateral hilar lymphadenectasis, and/or bilateral ankle arthritis or periarthritis.
Li, Xue, Liu, Jian, Liu, Meng, Liu, Min, Wang, Yu-Guang   +4 more
core   +2 more sources

Daqinjiao Decoction Ameliorates CSVD via RXR-γ/PPAR-γ/VEGF-α Pathway: Insights From Transcriptome Sequencing and Network Pharmacology. [PDF]

J Cell Mol Med
ABSTRACT Daqinjiao decoction (DQJD), an ancient traditional Chinese medicine formula, is clinically used in the treatment of cerebral small vessel disease (CSVD). However, the underlying molecular mechanisms by which DQJD exerts its therapeutic effects on CSVD remain elusive.
Lv M, Yang X, Shi X, Cao S, Li W, Zhou M, Gou X, Huang Y.   +7 more
europepmc   +2 more sources