A Review of the Botany, Traditional Use, Phytochemistry, Analytical Methods, Pharmacological Effects, and Toxicity of Angelicae Pubescentis Radix. [PDF]
Evid Based Complement Alternat Med, 2020 Angelicae Pubescentis Radix (AP), as a traditional Chinese medicine (TCM), has been used for thousands of years in China. In this paper, the botany, traditional use, phytochemistry, analytical methods, quality control, pharmacological effects, and toxicity of AP were reviewed. It can provide a reference for the further research and lay a foundation for
Yang L +9 more
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Comparison of Pharmacokinetic Profiles of 14 Major Bioactive Components in Normal and Arthritic Model Rats after Oral Administration of Angelicae pubescentis Radix by UPLC-MS/MS. [PDF]
Evid Based Complement Alternat Med, 2022 An ultraperformance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method was established to simultaneously determine 14 compounds of Angelicae pubescentis Radix (APR) in normal and arthritis rat plasma in which chloramphenicol and daidzein were used as the internal standards.
Hou A +8 more
europepmc +4 more sources
Anti-inflammatory and analgesic activity of r.a.p. (Radix Angelicae Pubescentis) ethanol extracts [PDF]
African journal of traditional, complementary, and alternative medicines : AJTCAM, 2013 The objective of this paper was to study the anti-inflammatory and analgesic effects of Radix Angelicae Pubescentis (R.A.P) ethanol extracts. Three classic anti-inflammatory models and two analgesic models were used in this research. In anti-inflammatory
Gao, L, Li, X, Wang, J
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Inhibitory Effects of Columbianadin on Nociceptive Behaviors in a Neuropathic Pain Model, and on Voltage-Gated Calcium Currents in Dorsal Root Ganglion Neurons in Mice [PDF]
Frontiers in Pharmacology, 2020 Radix angelicae pubescentis (RAP) has been used in Chinese traditional medicine to treat painful diseases such as rheumatism and headache. A previous study has reported that columbianadin (CBN), a major coumarin in RAP inhibits acute and inflammatory ...
Xiaolin Su +8 more
doaj +3 more sources
Optimization of the Purifying Process for Columbianetin-β-D-Glucopyranoside from Angelicae Pubescentis Radix and Evaluation of Its Analgesic Activity Using Hot Plate Test. [PDF]
Evid Based Complement Alternat Med, 2021 The objective of this work was to provide an economic and practical method for the purification of columbianetin-β-D-glucopyranoside from Angelicae Pubescentis Radix extract. In the static adsorption and desorption, the effects of resin type (D101, HP-20, AB-8, GDX-201, and DA201), contact time (10–360 min), and temperature (298–318 K) were assessed on
Zhang Y +6 more
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Phytomedicine Plus, 2023 Rheumatoid arthritis (RA) is a chronic systemic autoimmune disorder, mainly characterized by multiple joint diseases. The exact etiology is unclear; however, heredity, infection, and the external environment are considered to be influencing factors.
Rui Wang +3 more
doaj +3 more sources
Integrating Chinese Herbal Medicine into Conventional Care Was Related to Lower Risk of Sarcopenia Among Rheumatid Arthritis Patients: A Retrospective, Population-Based Study. [PDF]
J Multidiscip Healthc, 2023 Objective: Sarcopenia is a frequently observed comorbidity of rheumatoid arthritis (RA) due to the chronic activation of the innate immune system. Accumulating evidence has indicated that Chinese herbal medicine (CHM) safely suppresses proinflammatory ...
Li HH +6 more
europepmc +3 more sources
An Improved LC-MS/MS Method for Simultaneous Determination of the Eleven Bioactive Constituents for Quality Control of Radix Angelicae Pubescentis and Its Related Preparations [PDF]
The Scientific World Journal, 2015 An improved LC-MS/MS method was developed for simultaneous determination of eleven bioactive constituents of Radix Angelicae Pubescentis and its related preparations.
Jin Li +5 more
doaj +3 more sources
Comparison of Radix Angelicae pubescentis and Substitutes - Constituents and Inhibitory Effect on 5-lipoxygenase and Cyclooxygenase [PDF]
Pharmaceutical Biology, 1998 Various samples of Radix Angelicae pubescentis (Duhuo) and substitutes from the genera Angelica, Heracleum (Umbelliferae), and Aralia (Araliaceae) were analyzed for their constituents and inhibitory effect on cyclooxygenase (COX-1) and 5-lipoxygenase (5-LO).
J.H. Liu +3 more
openaire +3 more sources
The Tissue Distribution of Four Major Coumarins after Oral Administration of Angelicae Pubescentis Radix Extract to Rats Using Ultra-High-Performance Liquid Chromatography. [PDF]
Evid Based Complement Alternat Med, 2019 Angelicae pubescentis radix (APR) is widely applied in treating rheumatoid arthritis in China. Coumarins are the major active compounds of APR extract including columbianetin, columbianetin acetate, osthole, and columbianadin. The in vivo behavior of the four major coumarins of APR has not been systematically reported.
Ge Y +10 more
europepmc +3 more sources