Results 91 to 100 of about 49,086 (290)
Value co-creation in healthcare: evidence from innovative therapeutic alternatives for hereditary angioedema [PDF]
, 2018 Background Our research focuses on the co-creation of value in healthcare with reference to a case of hereditary angioedema with C1 inhibitor deficiency (C1-INH-HAE). Our work is mainly based on the concept of value co-creation in healthcare.
Barbarino, Alessandro +3 more
core +1 more source
Allergy, EarlyView.We show that direct single‐dose provocation test was both safe and effective in delabeling penicillin allergy in low‐risk adult patients, including those with mild delayed skin reactions and those with unknown reactions, such as childhood labels and past syncope episodes. In those who react in the drug provocation test, a T‐cell mechanism was confirmed
Marina Labella +7 more
wiley +1 more source
Development and content validity testing of a patient-reported outcomes questionnaire for the assessment of hereditary angioedema in observational studies [PDF]
, 2015 Background Hereditary Angioedema (HAE), a rare genetic disease, manifests as intermittent, painful attacks of angioedema. Attacks vary in frequency and severity and include skin, abdominal and life-threatening laryngeal swellings.
Bruce Zuraw +8 more
core +2 more sources
Efficacy of sacubitril/valsartan vs. enalapril at lower than target doses in heart failure with reduced ejection fraction: the PARADIGM-HF trial. [PDF]
, 2016 AimsIn this analysis, we utilized data from PARADIGM-HF to test the hypothesis that participants who exhibited any dose reduction during the trial would have similar benefits from lower doses of sacubitril/valsartan relative to lower doses of enalapril ...
Claggett, Brian +12 more
core +1 more source
Diagnosis and Treatment of Bradykinin-Mediated Angioedema: Outcomes from an Angioedema Expert Consensus Meeting [PDF]
, 2015 Several types of angioedema exist beyond hereditary angioedema (HAE) types I/II; however, the diagnostic and treatment needs of these conditions are not well understood.
Bernstein JA +4 more
core +1 more source
Angioneurotic edema: report of two cases
Brazilian Journal of Oral Sciences, 2015 Pediatric angioedema exhibits a different cause and clinical manifestations than does adult angioedema. Unlike angioedema in adults, pediatric angioedema is caused mostly due to food, followed by insect bites, infection and antibiotics.
Chaitra T.R. Telgi +2 more
doaj +1 more source
Diagnosis and Management of Hypersensitivity to Antiplatelet Drugs: EAACI Position Paper
Allergy, EarlyView.ABSTRACT Antiplatelet drug (APD) therapy is the cornerstone for the prevention of atherosclerotic cardiovascular disease. The main APDs are aspirin and thienopyridines, particularly clopidogrel. These drugs may induce hypersensitivity reactions (HSRs).
Gabriele Cortellini +10 more
wiley +1 more source
Paths reunited: initiation of the classical and lectin pathways of complement activation [PDF]
, 2010 Understanding the structural organisation and mode of action of the initiating complex of the classical pathway of complement activation (C1) has been a central goal in complement biology since its isolation almost 50 years ago.
Keeble, Anthony H. +4 more
core +1 more source
Clinics, 2018 Hereditary angioedema is an autosomal dominant disease characterized by recurrent angioedema attacks with the involvement of multiple organs. The disease is unknown to many health professionals and is therefore underdiagnosed.
Pedro Giavina-Bianchi +26 more
doaj +1 more source
Allergy, EarlyView.This study comprehended the allergen profiles of six edible crab species using proteomic and transcriptomic analyses and identified 11 putative allergens. King crab has a distinct protein and allergen profile, with the discovery of malate dehydrogenase as a novel king crab‐specific allergen registered as Para c 11.
Shanshan Li +11 more
wiley +1 more source