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Angioedema

Immunology and Allergy Clinics of North America, 2014
Urticarial wheals and angioedema are 2 different clinical symptoms. Both belong to various disease entities, and may occur in combination or be isolated. Increased vasodilation and vasopermeability is a common feature. Histamine and bradykinin are well-known mediators.
Konrad Börk
exaly   +3 more sources

Diagnosing Angioedema

Immunology and Allergy Clinics of North America, 2013
Angioedema usually occurs within the setting of allergic diseases or urticaria, but situations occur in which angioedema itself represents a disease, such as in hereditary angioedema. Evaluation of patients for recurrent angioedema without wheals must take into account both specific clinical signs and symptoms and specialized laboratory testing.
Andrea Zanichelli, Marco Cicardi
exaly   +3 more sources

Urticaria and Angioedema

Primary Care: Clinics in Office Practice, 2023
Urticaria and angioedema are caused by immunoglobulin E- and non-immunoglobulin E-mediated release of histamine and other inflammatory mediators from mast cells and basophils. Diagnosis is made clinically, and anaphylaxis must be ruled out if urticaria or angioedema is present.
Kate, Szymanski, Paul, Schaefer
openaire   +2 more sources

Angioedema

Dermatologic Clinics, 1985
Angioedema is characterized by a well-demarcated swelling on the skin, oropharyngolaryngeal tissue, or the gastrointestinal wall. Underlying mechanisms may include IgE-mediated reactions, complement activation, inhibition of the cyclo-oxygenase pathway of arachidonic acid metabolism, direct release of mediators from mast cells, and activation of the ...
J, Farnam, J A, Grant
openaire   +2 more sources

Recurrent angioedema in childhood: hereditary angioedema or histaminergic angioedema?

Pediatric Dermatology, 2020
AbstractBackgroundRecurrent angioedema is a rare entity during childhood. This study aimed to clarify differences between hereditary angioedema (HAE) and histaminergic angioedema (HA) in children.MethodsFifty‐seven children with HAE (male 36.8%, 8.9 years [5.4‐12.5]) and 42 children with recurrent HA (male 42.9%, 11.5 years [8.1‐16.8]) were analyzed ...
Melike Ocak   +6 more
openaire   +2 more sources

Angioedema

Journal of the American Academy of Dermatology, 2005
Although first described more than 130 years ago, the pathophysiology, origin, and management of the several types of angioedema are poorly understood by most dermatologists. Although clinically similar, angioedema can be caused by either mast cell degranulation or activation of kinin formation.
Allen P, Kaplan, Malcolm W, Greaves
openaire   +2 more sources

Angioedema

Pediatric Annals, 2019
Angioedema is a localized swelling of the skin and submucosal tissues and is generally benign and self-limiting. However, it can be life threatening if angioedema involves the upper airway, resulting in airway obstruction. Airway protection would be critical and lifesaving in patients with angioedema irrespective of the underlying etiology.
Divya, Seth, Deepak, Kamat
openaire   +2 more sources

Hereditary angioedema

Annals of Emergency Medicine, 1988
Although the condition is rare, patients with hereditary angioedema often present because of abdominal pain or airway compromise. A 27-year-old woman presented to the emergency department in acute abdominal distress. Identification of the disease in this patient allowed for proper management and avoidance of invasive procedures.
G P, Moore, W T, Hurley, S A, Pace
openaire   +2 more sources

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