Results 61 to 70 of about 50,655 (275)

Bradykinin-Mediated Angioedema [PDF]

New England Journal of Medicine, 2002
To the Editor: Angioedema is a nonitchy, pale swelling of subcutaneous or submucosal tissue that tends to recur chronically and can become life-threatening if the swelling occurs in the upper airwa...
J. Nussberger, M. Cugno, M. Cicardi
openaire   +2 more sources

Atopic Comorbidities Associated With Chronic Spontaneous Urticaria: A Case‐Control Analysis of the All of Us Research Program

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Chronic spontaneous urticaria (CSU) is a mast cell‐driven condition defined by recurrent wheals and/or angioedema lasting over 6 weeks without an identifiable trigger. Though CSU is known to co‐occur with atopic diseases and share Th2‐dominant immunologic pathways, prior studies have not adequately addressed these relationships in ...
Julian A. Cortes, Nana Ama Adjei‐Frimpong, Savannah K. Fakhouri, Francesco Delacqua, Reid Oldenburg   +4 more
wiley   +1 more source

Factor XII mutations, estrogen-dependent inherited angioedema, and related conditions

Allergy, Asthma & Clinical Immunology, 2010
The clinical, biochemical and genetic features of the conditions known as estrogen-dependent inherited angioedema, estrogen-associated angioedema, hereditary angioedema with normal C-1 inhibitor, type III angioedema, or factor XII angioedema are reviewed.
Binkley Karen E
doaj   +1 more source

SIAIP position paper: provocation challenge to antibiotics and non-steroidal anti-inflammatory drugs in children [PDF]

, 2018
Drug hypersensitivity reactions (DHRs) in childhood are mainly caused by betalactam or non-betalactam antibiotics, and non-steroidal anti-inflammatory drugs (NSAIDs).
Arasi, Stefania, Barni, Simona, Bottau, Paolo, Caffarelli, Carlo, Caimmi, Davide, Caimmi, Silvia, Cardinale, Fabio, Comberiati, Pasquale, Crisafulli, SEBASTIANO GIUSEPPE, Di Mauro, Dora, Diaferio, Lucia, Duse, Marzia, Franceschini, Fabrizio, Liotti, Lucia, Marseglia, Gianluigi, Mastrorilli, Carla, Mori, Francesca, Paravati, Francesco, Pelosi, Umberto, Saretta, Francesca   +19 more
core   +1 more source

Polyphenolic Activation of Basophils Explains Alcohol Hypersensitivity in AERD

The Laryngoscope, EarlyView.
The mechanism behind alcohol sensitivity in AERD has not been previously characterized. This study demonstrates the activation of basophils in patients with CRSwNP and AERD by polyphenolic compounds, but not ethanol. Since these compounds can be found in alcoholic beverages in similar frequencies by which they trigger symptoms, this research provides a
Spencer C. Payne, William Eschenbacher, Ryan Stepp, Larry Borish   +3 more
wiley   +1 more source

Angioedema: Clinical and Etiological Aspects

Clinical and Developmental Immunology, 2007
Angioedema is an abrupt swelling of the skin, mucous membrane, or both including respiratory and gastrointestinal tracts. This study aimed to report an experience of angioedema in a university hospital with respect to etiologies, clinical features ...
Kanokvalai Kulthanan, Sukhum Jiamton, Kanonrat Boochangkool, Kowit Jongjarearnprasert   +3 more
doaj   +1 more source

Angioedema in the emergency department: a practical guide to differential diagnosis and management

International Journal of Emergency Medicine, 2017
Background Angioedema is a common presentation in the emergency department (ED). Airway angioedema can be fatal; therefore, prompt diagnosis and correct treatment are vital.
Jonathan A. Bernstein, Paolo Cremonesi, Thomas K. Hoffmann, John Hollingsworth   +3 more
doaj   +1 more source

Bradykinin-induced angioedema in the emergency department

International Journal of Emergency Medicine, 2022
Background Acute airway angioedema commonly occurs through two distinct mechanisms: histamine- and bradykinin-dependent. Although they respond to distinct treatments, these two potentially life-threatening states present similarly.
Jacques Hébert, Jean-Nicolas Boursiquot, Hugo Chapdelaine, Benoit Laramée, Marylin Desjardins, Rémi Gagnon, Nancy Payette, Oleksandra Lepeshkina, Matthieu Vincent   +8 more
doaj   +1 more source

Gene List Selection Matters: Missed Diagnoses in Prenatal Exome Sequencing—PanelApp R21 and HPO‐Driven Versus OMIM‐Based Gene Lists

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To evaluate whether the causative variants found upon clinical exome sequencing in fetuses affected with selected structural anomalies would also be detected if PanelApp‐R21 or Human Phenotype Ontology (HPO)‐driven gene selection terms were applied instead.
Victoria Ardiles‐Ruesjas, Laia Rodriguez‐Revenga, Montse Pauta, Alfons Nadal, Gemma Arca, Laura Gort, Stiven Ernesto Sinisterra‐Díaz, Antoni Borrell   +7 more
wiley   +1 more source

Hereditary angioedema: A national investigation of associated comorbidities and surgical procedures

World Allergy Organization Journal
Background: Hereditary angioedema due to C1 inhibitor deficiency (HAE-C1INH) is characterized by sudden subcutaneous and/or submucosal angioedema attacks. C1 inhibitor is a serine protease inhibitor that regulates several enzyme cascade systems.
Lili Voloncs-Mindszenthy, MD, Hanga Réka Horváth, MD, Noémi Andrási, MD, Tamás Szilágyi, MD, Henriette Farkas, MD, PhD, DSc   +4 more
doaj   +1 more source