Results 171 to 180 of about 101,532 (231)

Population Pharmacokinetic/Pharmacodynamic Modeling of Donidalorsen, an Antisense Oligonucleotide in Development for Prophylaxis of Hereditary Angioedema. [PDF]

CPT Pharmacometrics Syst Pharmacol
Diep JK, Liu M, Singh P, Dorow S, Cohn DM, Bordone L, Newman KB, Gao X.   +7 more
europepmc   +1 more source

Characterization of missense variants in the signal peptide of C1 esterase inhibitor. [PDF]

J Allergy Clin Immunol
Ren Z, Bao J, Zhao S, Wedner HJ, Atkinson JP.   +4 more
europepmc   +1 more source

Impact of Oral Sebetralstat on Anxiety Associated With Hereditary Angioedema Attacks. [PDF]

Clin Exp Allergy
Craig T, Aygören-Pürsün E, Bernstein JA, Busse PJ, Caballero T, Cohn DM, Guilarte M, Farkas H, Jones DH, Kiani-Alikhan S, Manning ME, Maurer M, Riedl MA, Savic S, Wedner HJ, Yong PFK, Zanichelli A, van Kooten S, Iverson M, Hansen E, Hao J, Smith MD, Yea CM, Audhya PK, Lumry WR.   +24 more
europepmc   +1 more source

Garadacimab for the long-term prophylaxis of hereditary angioedema. [PDF]

J Dtsch Dermatol Ges
Aygören-Pürsün E, Treudler R, Staubach P, Saguer IM, Linhoff T, Magerl M.   +5 more
europepmc   +1 more source

Post Hoc Analysis of Recombinant C1 Inhibitor Clinical Data Using Contemporary Endpoints for Hereditary Angioedema. [PDF]

Adv Ther
Riedl MA, Narsipur N, Jones D, Tachdjian R, Relan A, Kilvert H, Aiello E, Habimana K, Roskell N, Gough A, Harper JR, Li HH, Harrington A.   +12 more
europepmc   +1 more source

Modeling Hereditary Angioedema With Personalized Expanded Potential Stem Cell-Derived Hepatocytes: A CRISPR-Validated Platform for Mutation-Specific Mechanisms and Therapeutic Innovation. [PDF]

Allergy
Liu X, Wang Y, Wong JCY, Zhang X, Wu C, Chen P, Yang Y, Liu P, Lau CS, Cook M, Li PH.   +10 more
europepmc   +1 more source

A Treat-to-Target approach in hereditary angioedema: expert consensus from a European committee. [PDF]

Front Immunol
Cancian M, Caballero T, Boccon-Gibod I, Buttgereit T, Cohn D, Eren E, Kiani-Alikhan S, Launay D, Mandelin J, Zanichelli A, Farkas H.   +10 more
europepmc   +1 more source

Donidalorsen for the Treatment of Hereditary Angioedema: A Review of Clinical Studies. [PDF]

Drug Des Devel Ther
Riedl MA, Craig T, Lumry WR, Bordone L, Treadwell S, Yarlas A, Newman KB, Cohn DM.   +7 more
europepmc   +1 more source

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Hereditary Angioedema

Immunology and Allergy Clinics of North America, 2022
Hereditary angioedema (HAE) is a rare autosomal dominant genetic disorder that usual results from a decreased level of functional C1-INH and clinically manifests with intermittent attacks of swelling of the subcutaneous tissue or submucosal layers of the respiratory or gastrointestinal tracts.
R Gentry, Wilkerson, Joseph J, Moellman
openaire   +3 more sources