Results 11 to 20 of about 499 (149)
Hereditary angioedema prevalence and satisfaction with prophylaxis in South Australia [PDF]
World Allergy Organization JournalBackground: Hereditary angioedema (HAE) due to deficiency of C1 Inhibitor (C1INH-HAE) is a rare, unpredictable and potentially fatal genetic disorder. There are relatively few systematic population prevalence studies, with reports from various countries ...
Alexander Troelnikov, MBBS +4 more
doaj +2 more sources
Pathophysiology of Hereditary Angioedema [PDF]
Pediatric Allergy, Immunology, and Pulmonology, 2014 The genetic deficiency of the C1 inhibitor is responsible for hereditary angioedema (HAE), which is a disease transmitted as an autosomal dominant trait. More than 200 point mutations in the C1 inhibitor gene have been found to be associated with HAE. Patients with this disease suffer from recurrent angioedema, which is mediated by bradykinin derived ...
S. Caccia, C. Suffritti, M. Cicardi
openaire +2 more sources
Clinical periodontal diagnosis
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi +5 more
wiley +1 more source
Optimum Use of Acute Treatments for Hereditary Angioedema: Evidence-Based Expert Consensus
Frontiers in Medicine, 2018 Acute treatment of hereditary angioedema due to C1 inhibitor deficiency has become available in the last 10 years and has greatly improved patients’ quality of life.
Hilary Longhurst
doaj +1 more source
Anais Brasileiros de Dermatologia, 2012 Hereditary Angioedema is a dominantly inherited disease. Routine screening of autoantibodies (AAB) is not recommended for individuals with Hereditary Angioedema; however, prevalence of these antibodies in Hereditary Angioedema patients is not well ...
Sergio Duarte Dortas Junior +7 more
doaj +1 more source
Pediatric hereditary angioedema [PDF]
Pediatric Allergy and Immunology, 2013 Abstract Hereditary angioedema ( HAE ) is a lifelong illness characterized by recurrent swelling of the skin, intestinal tract, and, ominously, the upper airway. It is caused by inadequate activity of the protein C1‐inhibitor, with dysfunction in the kallikrein/bradykinin ...
openaire +3 more sources
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1989 Hereditary angioedema is a rare disease, transmitted as an autosomal dominant trait. The disease usually manifests as acute subcutaneous or submucosal swellings and abdominal pain of two to five days duration. When localized to head or throat, life-threatening edema of the larynx may occur. The disease is caused by reduced amount of active C1 inhibitor.
A, Sabbah, I, Marsollier, V, Trouillard
+6 more sources
Anesthetic Management of Labor in a Woman with Hereditary Angioedema
Acta Médica PortuguesaN/a.
Inês P. Rodrigues +2 more
doaj +1 more source
Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients
British Journal of Clinical Pharmacology, EarlyView.Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel +12 more
wiley +1 more source