Results 101 to 110 of about 636 (203)

Cellular Responses to Tartrazine and Sulfanilic Acid Exposure in BEAS‐2B Cells: Viability, Apoptosis, and DNA Damage

Journal of Applied Toxicology, Volume 46, Issue 10, Page 3446-3454, October 2026.
ABSTRACT Tartrazine is a synthetic azo dye widely used in food, pharmaceutical, and cosmetic products, resulting in extensive human exposure, while its toxicity and that of its primary metabolite, sulfanilic acid, remain controversial. Considering the reported association of tartrazine with hypersensitivity and allergic‐like reactions, human bronchial ...
Merve Baysal, Abdullah Burak Karaduman, Büşra Korkut Çelikateş, Merve Güven, Özlem Atlı‐Eklioğlu, Sinem Ilgın   +5 more
wiley   +1 more source

A Cohort Study on Incidence and Factors Associated With Adverse Drug Reactions of Enalapril in Lusaka, Zambia

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Angiotensin‐converting enzyme inhibitors (ACEIs) are widely prescribed but are associated with adverse drug reactions (ADR), including angioedema, which is typically reported in 0.1%–0.7%. Data from sub‐Saharan Africa are limited. This study aimed to estimate the incidence and risk factors of enalapril‐associated ADRs in a Zambian cohort, with
Ntemena Yikon'a, Ngosa Mumba, Sarah Pedretti, Helen Hoenck, Jonathan Peter, Owen Ngalamika   +5 more
wiley   +1 more source

Emerging Paediatric Uses of Dupilumab Beyond Approvals

Clinical &Experimental Allergy, Volume 56, Issue 10, Page 1162-1176, October 2026.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese, Anna Calamita, Diletta D'Angelo, Alessia Marseglia, Esther Mesa Lombardero, Sara Pedersoli, Micol Tedeschi, Mara De Amici, Sara Manti, Valeria Brazzelli, Amelia Licari, Gian Luigi Marseglia   +11 more
wiley   +1 more source

Patch Testing in Paediatric Drug Hypersensitivity Reactions: Current Evidence and Clinical Implications

Contact Dermatitis, Volume 95, Issue 4, Page 349-357, October 2026.
ABSTRACT Drug hypersensitivity reactions (DHRs) are common in children and are diagnostically challenging, with cutaneous manifestations being the most common presentation. Patch testing (PT) is a well‐established tool for investigating delayed T‐cell‐mediated reactions and is widely used in patients with contact dermatitis.
Gabriele Simonetti, Francesco Catamerò, Giulia Liccioli, Leonardo Tomei, Simona Barni, Mattia Giovannini, Lucrezia Sarti, Francesca Mori   +7 more
wiley   +1 more source

Chronic Spontaneous Urticaria and Psychiatric Symptoms: The Blood–Brain Barrier Hypothesis

Experimental Dermatology, Volume 35, Issue 10, October 2026.
ABSTRACT Chronic spontaneous urticaria (CSU) is a mast cell‐driven inflammatory disease frequently accompanied by anxiety, depression, sleep disturbance, fatigue, and impaired quality of life. Pruritus, disturbed sleep, psychosocial burden, and treatment‐related effects are established contributors to this neuropsychiatric and functional burden ...
Gerasimos N. Konstantinou, Jerry J. Warsh, Daniel M. Blumberger, Stefan Kloiber, George N. Konstantinou   +4 more
wiley   +1 more source

CH50 as a Clinically Useful Biomarker of Disease Activity and Antihistamine Resistance in Chronic Spontaneous Urticaria: An Observational Ambispective Single‐Center Study

International Journal of Dermatology, Volume 65, Issue 10, Page 2066-2073, October 2026.
Personalized CSU care guided by CH50. ABSTRACT Background Chronic spontaneous urticaria (CSU) is frequently refractory to guideline‐based therapy, highlighting the need for predictive biomarkers. Dysregulation of the complement system has been implicated in CSU severity, but global complement activity has not been systematically evaluated.
Nidia Planella‐Fontanillas, Emilio Berna‐Rico, David Pesqué, Evelyn Andrades, Silvia Sánchez, Paloma Torres‐Bosó, Ramon Gimeno, Fernando Gallardo, Ramon M. Pujol, Ana M. Giménez‐Arnau   +9 more
wiley   +1 more source

Acquired angioedema. Case report [PDF]

, 2019
Introducción: el angioedema adquirido es una rara enfermedad. Se clasifica en hereditario y adquirido. Las causas son variadas, pueden ser secundarios a enfermedades autoinmunes, síndromes linfoproliferativos y otras neoplasias.
López Ruiz, Osmany, Oyarzábal Guerra, Luis Felipe, Oyarzábal Guerra, Augusto   +2 more
core   +3 more sources

Evaluation of the frequency of anxiety, depression, illness perception, and quality of life in patients with inborn errors of immunity (primary immunodeficiencies)

Introdução: Os Erros Inatos da Imunidade (EII) fazem parte de um conjunto de doenças crônicas, geralmente hereditárias, que comprometem a imunidade inata dos portadores, o deixando vulnerável diante de vírus, fungos ou bactérias, acarretando em ...
Jecks, Mellina Harue Shima
core   +1 more source

Angioedèmes histaminiques versus bradykiniques : mortalité par asphyxie

, 2017
Prix de thèse de l'UFR de médecine de Grenoble : 2018Introduction: Isolated head and neck angioedema (AE) can have one of two major etiologic mechanisms: bradykinic, due to a congenital anomaly or acquired defective bradykinin metabolism, or histaminic ...
Crochet, Julia
core  

The peri-operative management of patients with hereditary angioedema requiring dental treatment: a case series. [PDF]

Br Dent J
Murray N, Geddis-Regan A.
europepmc   +1 more source