Results 81 to 90 of about 594 (209)
Clinical &Experimental Allergy, EarlyView.Pooled analysis of the phase 3 APeX‐2 and APeX‐J trials evaluated the impact of berotralstat 150 mg on health‐related quality of life in patients with hereditary angioedema using the Angioedema Quality of Life (AE‐QoL) questionnaire. Berotralstat significantly improved AE‐QoL total and domain scores for daily functioning and fears/shame versus placebo ...
Teresa Caballero +11 more
wiley +1 more source
Algorithms in Allergy: Hereditary Angioedema
Allergy, EarlyView.
Konrad Bork +3 more
wiley +1 more source
Clinical Otolaryngology, EarlyView.ABSTRACT Objective To characterize paediatric hospitalizations for angioedema and identify the prevalence and outcomes of airway interventions using a large national database. Methods We performed a cross‐sectional analysis of the Kids' Inpatient Database (2003–2019), including paediatric patients (0–20 years) hospitalized with angioedema identified by
Saharsh Talwar +4 more
wiley +1 more source
Contact Dermatitis, EarlyView.ABSTRACT Drug hypersensitivity reactions (DHRs) are common in children and are diagnostically challenging, with cutaneous manifestations being the most common presentation. Patch testing (PT) is a well‐established tool for investigating delayed T‐cell‐mediated reactions and is widely used in patients with contact dermatitis.
Gabriele Simonetti +7 more
wiley +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Background Wheat‐dependent exercise‐induced anaphylaxis (WDEIA) occurs after ingestion of wheat/gluten in the presence of various cofactors. Here, we characterized the sensitization spectrum to various wheat flours, as revealed by skin prick test (SPT) and specific IgE (sIgE) against wheat flour, gluten, and various wheat components.
Enna M. Schwarze +3 more
wiley +1 more source
Garadacimab for the long‐term prophylaxis of hereditary angioedema
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Hereditary angioedema (HAE), a rare and debilitating disease characterized by recurrent and spontaneous attacks of tissue swelling, has a high unmet therapeutic need, with many patients experiencing insufficient disease control with current prophylactic treatments.
Emel Aygören‐Pürsün +5 more
wiley +1 more source
Completion of the Icatibant Outcome Survey and What We Learned
Clinical &Experimental Allergy, EarlyView.
Laurence Bouillet +8 more
wiley +1 more source
Gene Editing for Haemophilia—The Next Frontier
Haemophilia, EarlyView.ABSTRACT The recently approved haemophilia A and B gene therapies via adeno‐associated virus (AAV) showed a promising therapeutic response after a single injection, but there are still limitations, including the potential loss of transgene expression and restriction in adults.
Mirko Pinotti +3 more
wiley +1 more source
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Objective This study aimed to evaluate demographic characteristics, treatment effectiveness, and safety outcomes in patients with migraine undergoing anti‐calcitonin gene‐related peptide (CGRP) treatments regarding the presence of autoimmune diseases. Background CGRP has an important role in migraine pathophysiology through neuronal modulation
María Clara García‐Castillo +37 more
wiley +1 more source