Results 221 to 230 of about 354,639 (240)
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Current Opinion in Biotechnology, 2007
Angiogenesis represents the formation of new capillaries by cellular outgrowth from existing microvessels and plays a critical role in the response to ischemia associated with peripheral arterial disease and myocardial infarction. Imaging of angiogenesis would be valuable in risk stratification of patients with arterial occlusive disease.
Lawrence W, Dobrucki, Albert J, Sinusas
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Angiogenesis represents the formation of new capillaries by cellular outgrowth from existing microvessels and plays a critical role in the response to ischemia associated with peripheral arterial disease and myocardial infarction. Imaging of angiogenesis would be valuable in risk stratification of patients with arterial occlusive disease.
Lawrence W, Dobrucki, Albert J, Sinusas
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Frontiers in Bioscience, 1998
Therapeutic angiogenesis constitutes a fundamental survival mechanism that acts to preserve the integrity of tissues subjected to ischemia. Supplemental administration of angiogenic cytokines--as recombinant protein or plasmid DNA--have been shown to augment collateral development when endogenous angiogenesis is suboptimal for organ function, and thus ...
J M, Isner, A, Takayuki
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Therapeutic angiogenesis constitutes a fundamental survival mechanism that acts to preserve the integrity of tissues subjected to ischemia. Supplemental administration of angiogenic cytokines--as recombinant protein or plasmid DNA--have been shown to augment collateral development when endogenous angiogenesis is suboptimal for organ function, and thus ...
J M, Isner, A, Takayuki
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2011
The angiogenic process is central in the pathogenesis of various diseases. The in vitro and in vivo monitoring of the neovascular process is essential for the development and evaluation of angiogenesis inhibitors or stimulators. Since no single method exists that can assess angiogenesis in a robust, reliable, and reproducible fashion, researchers often
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The angiogenic process is central in the pathogenesis of various diseases. The in vitro and in vivo monitoring of the neovascular process is essential for the development and evaluation of angiogenesis inhibitors or stimulators. Since no single method exists that can assess angiogenesis in a robust, reliable, and reproducible fashion, researchers often
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Current Oncology Reports, 2000
Angiogenesis inhibitors target the neovascular development that is hypothesized to underlie tumor growth. The inhibitors that are undergoing the clinical testing phase can be divided into five categories based on their target activity: 1) drugs that block matrix breakdown; 2) drugs that inhibit endothelial cells directly; 3) drugs that block ...
T R, Tennant +2 more
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Angiogenesis inhibitors target the neovascular development that is hypothesized to underlie tumor growth. The inhibitors that are undergoing the clinical testing phase can be divided into five categories based on their target activity: 1) drugs that block matrix breakdown; 2) drugs that inhibit endothelial cells directly; 3) drugs that block ...
T R, Tennant +2 more
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2016
Neoangiogenesis constitutes one of the first steps of tumor progression beyond a critical size of tumor growth, which supplies a dormant mass of cancerous cells with the required nutrient supply and gaseous exchange through blood vessels essentially needed for their sustained and aggressive growth.
Dhanya K, Nambiar +2 more
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Neoangiogenesis constitutes one of the first steps of tumor progression beyond a critical size of tumor growth, which supplies a dormant mass of cancerous cells with the required nutrient supply and gaseous exchange through blood vessels essentially needed for their sustained and aggressive growth.
Dhanya K, Nambiar +2 more
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Angiogenesis and anti-angiogenesis in neuroblastoma
European Journal of Cancer, 2002Angiogenesis is a biological process by which new capillaries are formed from pre-existing vessels. It occurs in physiological and pathological conditions, such as tumours, where a specific critical turning point is the transition from the avascular to the vascular phase.
RIBATTI, Domenico +5 more
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Angiogenesis-dependent diseases and angiogenesis therapy
Pathology & Oncology Research, 2001The discovery of the molecular mechanisms of physiological vasculogenesis and pathological angiogenesis helped to recognize two classes of diseases: one where the therapeutic angiogenesis can repair the tissue damages (arteriosclerosis, myocardial infarction, limb ischemia) and the other one where inhibition of pathological angiogenesis can cure the ...
J, Tímár +4 more
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Head & Neck, 1996
The growth of solid tumors, including head and neck squamous cell carcinomas, depends on the establishment of a blood supply within the tumor (neovascularization or angiogenesis). For this process to take place, tumors produce growth factors which stimulate the proliferation, migration, and differentiation of endothelial cells. These growth factors are
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The growth of solid tumors, including head and neck squamous cell carcinomas, depends on the establishment of a blood supply within the tumor (neovascularization or angiogenesis). For this process to take place, tumors produce growth factors which stimulate the proliferation, migration, and differentiation of endothelial cells. These growth factors are
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Angiogenesis: Perspectives from Therapeutic Angiogenesis
2020Peripheral arterial disease (PAD) is a major complication of systemic atherosclerosis and is a major public health threat worldwide. For patients with PAD, there are limited options for therapy, and no medications have been shown to slow progression of the disease.
Monique Bethel +2 more
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2001
Angiogenesis-the formation of a vascular network-is essential for the support of a developing tumor when simple diffusion of nutrients is impossible. The ability of a solid tumor to achieve metabolic needs beyond simple diffusion is dependent on the development of this neovascular network.
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Angiogenesis-the formation of a vascular network-is essential for the support of a developing tumor when simple diffusion of nutrients is impossible. The ability of a solid tumor to achieve metabolic needs beyond simple diffusion is dependent on the development of this neovascular network.
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