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Angiogenesis and anti-angiogenesis in hepatocellular carcinoma

Cancer Treatment Reviews, 2006
Experimental and clinical data indicate that in human hepatocellular carcinoma (HCC) tumor progression is associated with angiogenesis and that an increase in microvascular density is associated with a poor prognosis. This review summarizes the literature concerning the relationship between angiogenesis and progression in HCC.
RIBATTI, Domenico   +4 more
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Angiogenesis

Seminars in Reproductive Medicine, 1997
Endometriosis remains a significant cause of pain and ill health for women and is a significant factor in reducing quality of life for women. The ability of desquamated endometrium to attach and implant within the peritoneal cavity is dependent upon its ability to establish and maintain an adequate blood supply.
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Angiogenesis and Anti-Angiogenesis in Hematological Malignancies

Journal of Hematotherapy & Stem Cell Research, 2003
Although it is well established that the growth of solid tumors requires vigorous neovascularization, it has been assumed that leukemias and other hematological malignancies do not depend on angiogenesis. However, the role of angiogenesis in growth and survival of neoplastic cells of the hematopoietic system has recently been recognized, and provides a
RIBATTI, Domenico   +3 more
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Angiogenesis-dependent diseases and angiogenesis therapy

Pathology & Oncology Research, 2001
The discovery of the molecular mechanisms of physiological vasculogenesis and pathological angiogenesis helped to recognize two classes of diseases: one where the therapeutic angiogenesis can repair the tissue damages (arteriosclerosis, myocardial infarction, limb ischemia) and the other one where inhibition of pathological angiogenesis can cure the ...
J, Tímár   +4 more
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NO and angiogenesis

Atherosclerosis Supplements, 2003
Angiogenesis requires the elaboration of endothelium-derived nitric oxide (NO). Angiogenic factors induce the release of NO from endothelial cells, which mediates a multiplicity of processes involved in angiogenesis. These NO-modulated processes include endothelial cell survival, proliferation, migration, and interaction with the extracellular matrix ...
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Surgery and angiogenesis

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2004
Surgery may be regarded as an angiogenesis-inducing condition since it evokes the release of many angiogenic factors. Regarding the mechanistic overlap between tumor-associated neovascularisation and (physiological) angiogenesis in response to injury and hypoxia, surgery may promote the uncontrolled growth of residual dormant tumor cells.
Jarmila D W, van der Bilt   +1 more
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Angiogenesis

Pancreatology, 2010
The rapid growth of cancer cells, such as the case with pancreatic cancer cells, requires new blood vessel growth to sustain tumor viability. In fact, angiogenesis has been found to be closely correlated with rapid tumor growth and a poorer prognosis in pancreatic cancer.
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Angiogenesis in transgenic models of multistep angiogenesis

2004
The histopathology and the epidemiology of human cancers, as well as studies of animal models of tumorigenesis, have led to a widely accepted notion that multiple genetic and epigenetic changes have to accumulate for progression to malignancy. Formation of new blood vessels (tumor angiogenesis) has been recognized, in addition to proliferative ...
Radovanovic I, D'Angelo MG, Aguzzi A
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Angiogenesis of the ovary

American Journal of Obstetrics and Gynecology, 2000
We present current data pertaining to angiogenesis of the ovary throughout the follicular and luteal phases of the ovarian cycle, in various ovarian pathologic conditions and in benign and neoplastic diseases. MEDLINE, Current Contents, and Index Medicus were searched for studies published between January 1966 and October 1998.
O, Abulafia, D M, Sherer
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Angiogenesis and angiogenesis inhibition: An overview

1997
The study of angiogenesis attracts investigators from many different fields who find that regulation of blood vessel growth underlies a wide spectrum of biologic processes. These include reproduction, development, repair, angiogenic diseases, and cancer (Folkman, 1995).
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