Results 211 to 220 of about 486,070 (267)

Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

Advanced Science, EarlyView.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li, Zhongya Zhai, Haiyi Yu, Renjie Qiu, Fengyu Li, Luxi Xiao, Boxi Huang, Huiying Liu, Jiayong He, Bowen Cai, Jiawen Chen, Jiang Yu, Guoxin Li, Tao Chen   +13 more
wiley   +1 more source

Bioinspired Polymeric Scaffolds for Improvement of Angiogenesis and Tissue Engineering: A Review. [PDF]

Polymers (Basel)
Jigar V, Nensi R, Puja V, Prajapati B, Panraksa P, Singh S, Chittasupho C.   +6 more
europepmc   +1 more source

Quality Thresholds for Angiogenesis Under Acoustic Manipulation in Engineered Vascular Tissues

Advanced Science, EarlyView.
Defined biological and physical quality thresholds achieved through acoustic manipulation regulate cellular alignment and spatial organization, promoting self‐assembling vasculature, extracellular matrix deposition, and angiogenic responses, thereby establishing critical acoustic patterning requirements for engineered vascular tissue development in ...
Oscar O'Dwyer Lancaster‐Jones, Russell Quinn, Niloofar Khoshdel Rad, Kilian Paul, Andrea Frank, Daniela F. Duarte Campos   +5 more
wiley   +1 more source

Transcriptomic characters of cochlear vascular cells with pericyte-driven angiogenetic activity. [PDF]

Angiogenesis
Wang P, Zhang Y, Hou Z, Zhang J, Sharma K, Shi X.   +5 more
europepmc   +1 more source

An Integrative Strategy Delineates Modular Metabolic Remodeling and Potential Therapeutic Targets Across Metabolic Diseases

Advanced Science, EarlyView.
An integrative single‐cell atlas across multiple metabolic diseases reveals coordinated metabolic modules and disease‐shared versus disease‐specific pathway activities. By systematically comparing scoring strategies, a robust RankAve framework is established. Coupled with network analysis and drug‐target prediction, this resource uncovers cross‐disease
Kuan Yang, Congxue Hu, Hang Zhao, Xiao Peng, Yiming Yan, Jiasi Wang, Wenqi Jiang, Depeng Mu, Yan Cao, Xia Li, Yunpeng Zhang   +10 more
wiley   +1 more source

Diabetes and Delayed Wound Healing: Molecular Mechanisms and Dermatological Interventions. [PDF]

Int Wound J
Jreije S, Fadel M, Karam C, Ghadieh HE, Ghanem A.   +4 more
europepmc   +1 more source

Mechanobiology of solid tumor vasculature: implications for tumor progression. [PDF]

Cancer Metastasis Rev
Kondapaneni RV, Libring S, Dsa S, Reinhart-King CA.   +3 more
europepmc   +1 more source

Reactive Nitrogen-Dominant Plasma Accelerates Diabetic Wound Healing Through Regulated Angiogenesis and TGF-β Normalisation. [PDF]

Int Wound J
Cheng YP, Chou-Huang TY, Lee CC, Chen HL, Cheng KY, Wu MC, Huang SS, Guo JW, Wu JS.   +8 more
europepmc   +1 more source

CreER activation transiently disrupts angiogenesis by reducing proliferation and promoting apoptosis in vascular endothelial cells. [PDF]

Angiogenesis
Ioannou E, Dong M, Rashbrook VS, Ruhrberg C, Rudnicki M.   +4 more
europepmc   +1 more source

HIF1-driven TDP-43 stabilizes TRIP6 mRNA to drive angiogenesis and colorectal cancer progression under hypoxia. [PDF]

Transl Oncol
Cheng K, Liu Y, Feng W, Xu D, Hao B.
europepmc   +1 more source