Results 281 to 290 of about 519,126 (297)
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Current Oncology Reports, 2000
Angiogenesis inhibitors target the neovascular development that is hypothesized to underlie tumor growth. The inhibitors that are undergoing the clinical testing phase can be divided into five categories based on their target activity: 1) drugs that block matrix breakdown; 2) drugs that inhibit endothelial cells directly; 3) drugs that block ...
T R, Tennant +2 more
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Angiogenesis inhibitors target the neovascular development that is hypothesized to underlie tumor growth. The inhibitors that are undergoing the clinical testing phase can be divided into five categories based on their target activity: 1) drugs that block matrix breakdown; 2) drugs that inhibit endothelial cells directly; 3) drugs that block ...
T R, Tennant +2 more
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2016
Neoangiogenesis constitutes one of the first steps of tumor progression beyond a critical size of tumor growth, which supplies a dormant mass of cancerous cells with the required nutrient supply and gaseous exchange through blood vessels essentially needed for their sustained and aggressive growth.
Dhanya K, Nambiar +2 more
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Neoangiogenesis constitutes one of the first steps of tumor progression beyond a critical size of tumor growth, which supplies a dormant mass of cancerous cells with the required nutrient supply and gaseous exchange through blood vessels essentially needed for their sustained and aggressive growth.
Dhanya K, Nambiar +2 more
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Angiogenesis and anti-angiogenesis in neuroblastoma
European Journal of Cancer, 2002Angiogenesis is a biological process by which new capillaries are formed from pre-existing vessels. It occurs in physiological and pathological conditions, such as tumours, where a specific critical turning point is the transition from the avascular to the vascular phase.
RIBATTI, Domenico +5 more
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Angiogenesis-dependent diseases and angiogenesis therapy
Pathology & Oncology Research, 2001The discovery of the molecular mechanisms of physiological vasculogenesis and pathological angiogenesis helped to recognize two classes of diseases: one where the therapeutic angiogenesis can repair the tissue damages (arteriosclerosis, myocardial infarction, limb ischemia) and the other one where inhibition of pathological angiogenesis can cure the ...
J, Tímár +4 more
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Head & Neck, 1996
The growth of solid tumors, including head and neck squamous cell carcinomas, depends on the establishment of a blood supply within the tumor (neovascularization or angiogenesis). For this process to take place, tumors produce growth factors which stimulate the proliferation, migration, and differentiation of endothelial cells. These growth factors are
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The growth of solid tumors, including head and neck squamous cell carcinomas, depends on the establishment of a blood supply within the tumor (neovascularization or angiogenesis). For this process to take place, tumors produce growth factors which stimulate the proliferation, migration, and differentiation of endothelial cells. These growth factors are
openaire +2 more sources
Angiogenesis: Perspectives from Therapeutic Angiogenesis
2020Peripheral arterial disease (PAD) is a major complication of systemic atherosclerosis and is a major public health threat worldwide. For patients with PAD, there are limited options for therapy, and no medications have been shown to slow progression of the disease.
Monique Bethel +2 more
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2001
Angiogenesis-the formation of a vascular network-is essential for the support of a developing tumor when simple diffusion of nutrients is impossible. The ability of a solid tumor to achieve metabolic needs beyond simple diffusion is dependent on the development of this neovascular network.
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Angiogenesis-the formation of a vascular network-is essential for the support of a developing tumor when simple diffusion of nutrients is impossible. The ability of a solid tumor to achieve metabolic needs beyond simple diffusion is dependent on the development of this neovascular network.
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1974
The hypothesis that tumors are angiogenesis dependent has, in the past decade, generated new investigations designed to elucidate the mechanism of angiogenesis itself. Many laboratories are now engaged in this pursuit. Some are studying angiogenesis that occurs in physiological situations, whereas others are interested in angiogenesis that dominates ...
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The hypothesis that tumors are angiogenesis dependent has, in the past decade, generated new investigations designed to elucidate the mechanism of angiogenesis itself. Many laboratories are now engaged in this pursuit. Some are studying angiogenesis that occurs in physiological situations, whereas others are interested in angiogenesis that dominates ...
openaire +3 more sources
Recenti progressi in medicina, 1999
The formation of new vessels, (angiogenesis) characterizes body development and is pivotal in some diseases. In particular, angiogenesis is crucial for the growth of tumors and metastasis diffusion. The beginning of tumor angiogenesis is caused by the selection of a cancer cell clone which induces an unbalance between inducers and inhibitors of ...
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The formation of new vessels, (angiogenesis) characterizes body development and is pivotal in some diseases. In particular, angiogenesis is crucial for the growth of tumors and metastasis diffusion. The beginning of tumor angiogenesis is caused by the selection of a cancer cell clone which induces an unbalance between inducers and inhibitors of ...
openaire +2 more sources