Results 41 to 50 of about 952,689 (432)

Angiotensin II and VEGF are Involved in Angiogenesis Induced by Short-Term Exercise Training [PDF]

, 2001
Results from our laboratory have suggested a pathway involving angiotensin II type 1 (AT1) receptors and vascular endothelial growth factor (VEGF) in angiogenesis induced by electrical stimulation.
Amaral, Sandra L., Greene, Andrew S., Papanek, Paula   +2 more
core   +2 more sources

Impaired tumor growth and angiogenesis in mice heterozygous for Vegfr2 (Flk1) [PDF]

, 2018
VEGF signaling through its tyrosine kinase receptor, VEGFR2 (FLK1), is critical for tumor angiogenesis. Previous studies have identified a critical gene dosage effect of VegfA in embryonic development and vessel homeostasis, neovascularization, and tumor
Choi, Kyunghee, Oladipupo, Sunday S, Ornitz, David M, Smith, Craig, Ul Kabir, Ashraf   +4 more
core   +3 more sources

The role of microenvironment in tumor angiogenesis

Journal of experimental & clinical cancer research : CR, 2020
Tumor angiogenesis is necessary for the continued survival and development of tumor cells, and plays an important role in their growth, invasion, and metastasis.
Xianjie Jiang, Jie Wang, Xiangying Deng, F. Xiong, Shanshan Zhang, Zhaojian Gong, Xiayu Li, K. Cao, H. Deng, Yi He, Q. Liao, Bo Xiang, Ming Zhou, Can Guo, Zhaoyang Zeng, Gui-yuan Li, Xiaoling Li, W. Xiong   +17 more
semanticscholar   +1 more source

Meta‐analysis of clinical metabolic profiling studies in cancer: challenges and opportunities

EMBO Molecular Medicine, 2016
Cancer cell metabolism has received increasing attention. Despite a boost in the application of clinical metabolic profiling (CMP) in cancer patients, a meta‐analysis has not been performed.
Jermaine Goveia, Andreas Pircher, Lena‐Christin Conradi, Joanna Kalucka, Vincenzo Lagani, Mieke Dewerchin, Guy Eelen, Ralph J DeBerardinis, Ian D Wilson, Peter Carmeliet   +9 more
doaj   +1 more source

Disruption of VEGF Mediated Flk‐1 Signaling Leads to a Gradual Loss of Vessel Health and Cardiac Function During Myocardial Infarction: Potential Therapy With Pellino‐1

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background The present study demonstrates that the ubiquitin E3 ligase, Pellino‐1 (Peli1), is an important angiogenic molecule under the control of vascular endothelial growth factor (VEGF) receptor 2/Flk‐1.
Mahesh Thirunavukkarasu, Vaithinathan Selvaraju, Mandip Joshi, Vladimir Coca‐Soliz, Leonidas Tapias, IbnalWalid Saad, Craig Fournier, Aaftab Husain, Jacob Campbell, Siu‐Pok Yee, Juan A. Sanchez, J. Alexander Palesty, David W. McFadden, Nilanjana Maulik   +13 more
doaj   +1 more source

Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells. [PDF]

, 2014
To enable new blood vessel growth, endothelial cells (ECs) express neuropilin 1 (NRP1), and NRP1 associates with the receptor tyrosine kinase VEGFR2 after binding the vascular endothelial growth factor A (VEGF) to enhance arteriogenesis.
Alessandro Fantin, Anastasia Lampropoulou, Anissa Chikh, Anselmi, Ballmer-Hofer, Baruzzi, Birukova, Buchdunger, Campochiaro, Carmeliet, Casanovas, Chen, Chen, Chislock, Cho, Choi, Christiana Ruhrberg, Clark, Claudio Raimondi, Colicelli, Connor, Cui, Cujec, Dejana, Druker, Fantin, Fantin, Fantin, Fantin, Foxton, Fukasawa, Gerhardt, Gerhardt, Herzog, Kawamura, Kawasaki, Kim, Kitsukawa, Koch, Lanahan, Lanahan, Laura Denti, Lewis, Lewis, Mamluk, Murga, Nishijima, Pan, Pan, Parsons, Pasapera, Phng, Raimondi, Ren, Robinson, Roig, Rosenfeld, Ruhrberg, Ruhrberg, Saint-Geniez, Salikhova, Shimizu, Shojaei, Smith, Soker, Sottile, Stenzel, Tvorogov, Uemura, Valdembri, Wang, Welti, Yaqoob, Zaidel-Bar, Zhuang   +74 more
core   +4 more sources

A transgenic Xenopus laevis reporter model to study lymphangiogenesis

Biology Open, 2013
Summary The importance of the blood- and lymph vessels in the transport of essential fluids, gases, macromolecules and cells in vertebrates warrants optimal insight into the regulatory mechanisms underlying their development.
Annelii Ny, Wouter Vandevelde, Philipp Hohensinner, Manu Beerens, Ilse Geudens, Antonio Diez-Juan, Katleen Brepoels, Stéphane Plaisance, Paul A. Krieg, Tobias Langenberg, Stefan Vinckier, Aernout Luttun, Peter Carmeliet, Mieke Dewerchin   +13 more
doaj   +1 more source

Reduced FRG1 expression promotes angiogenesis via activation of the FGF2‐mediated ERK/AKT pathway

FEBS Open Bio, 2023
Identifying novel targets that control both tumorigenesis and angiogenesis can aid in developing a more potent anti‐angiogenic therapeutic strategy. We previously reported that reduction of FRG1 is associated with increased p38‐MAPK signaling in prostate
Bratati Mukherjee, Pratush Brahma, Talina Mohapatra, Saurabh Chawla, Manjusha Dixit   +4 more
doaj   +1 more source

Rescue of Pressure Overload-Induced Heart Failure by Estrogen Therapy. [PDF]

, 2016
BackgroundEstrogen pretreatment has been shown to attenuate the development of heart hypertrophy, but it is not known whether estrogen could also rescue heart failure (HF).
Bopassa, Jean C, Centala, Alexander, Eghbali, Mansoureh, Iorga, Andrea, Li, Jingyuan, Nadadur, Rangarajan D, Ren, Shuxun, Saito, Tomoaki, Sharma, Salil, Stefani, Enrico, Toro, Ligia, Umar, Soban, Wang, Yibin   +12 more
core   +1 more source

Angiogenesis in Disease

International Journal of Molecular Sciences, 2022
Angiogenesis is a multi-step process by which new blood capillaries are formed starting from preexisting functional vessels [...]
La Mendola D., Trincavelli M. L., Martini C.   +2 more
openaire   +3 more sources